1)     国家自然科学基金委基础科学中心项目A类。项目名称：精子发生与早期胚胎发育调控及出生缺陷病因研究；起止年月：2025年01月-2029年12月；项目编号：32488101；项目经费：1100万元；学术骨干：刘默芳。

2)     新基石研究员项目。项目名称：精子发生关键调控机制及男性不育新病因研究；起止年月：2024年01月-2028年12月；项目编号：NCI202329；项目经费2500万；项目负责人：刘默芳。

3)     上海市科委基础研究领域重点项目。项目名称：RNA调控在精子形成及男性不育中的新功能机制研究；起止年月：2023年12月-2026年11月；项目编号：23JC1403801；项目经费300万；项目首席科学家：刘默芳。

4)     国家自然科学基金委重点项目。项目名称：功能性piRNA鉴定及piRNA调控规则研究；起止年月：2024年1月-2028年12月；项目编号：32330053； 项目经费：232万；项目负责人：刘默芳。

5)     上海市东方英才团队项目。项目名称：RNA调控与男性生殖健康；起止年月：2024年01月-2027年12月；项目编号：E35B62010；项目经费700万；项目负责人：刘默芳。

6)     国家重点研发计划 “生物大分子与微生物组” 重点专项项目。项目名称：非编码RNA及其非经典翻译的功能机制；项目编号： 2022YFA1303300；起止年月：2022/09-2027/8；项目经费：400万；学术骨干：刘默芳。

1)     Quansheng Du, Xin Wang, Yangming Wang, Mo-FangLiu*, Xiaofeng Cao*. Empowering Drug InnovationThrough Fundamental RNA Research in China. Nat Chem Biol, 2026Mar 12. doi: 10.1038/s41589-026-02173-6. Online ahead of print.

2)      Duo Pan, Mo-Fang Liu*. tRNA intron-derived smallregulatory RNAs fine-tune gene expression under oxidative stress. MolCell, 2025, 85(4): 669-671.

3)      ShouhongGuang S, Mo-Fang Liu*. The discovery of tiny RNAs that have crucialroles. Sci China Life Sci, 2025, 68(4):1183-1185.

4)      Huan Wei, JieGao, Di-Hang Lin, Ruirong Geng, Jiaoyang Liao, Tian-Yu Huang, Guanyi Shang,Jiongjie Jing, Zong-Wei Fan, Duo Pan, Zi-Qi Yin, Tianming Li, Xinyu Liu, ShuangZhao, Chen Chen, Jinsong Li, Xin Wang*, Deqiang Ding* and Mo-Fang Liu*.piRNA loading triggers MIWI translocation from the intermitochondrial cement tochromatoid body during mouse spermatogenesis. Nat Commun, 2024, 15(1):2343.

5)     Xin Wang*, Zhen-Yi Zhang,Shuang Zhao, Mo-Fang Liu*. New insights intosmall non-coding RNAs during spermatogenesis. Sci Bull (Beijing). 2024, 69(11):1581-1585. 

6)      Ke Wu, FengxiaoBu, Yang Wu, Gen Zhang, Xin Wang, Shunmin He, Mo-Fang Liu*, RunshengChen*, Huijun Yuan*. Exploring noncoding variants in genetic diseases: Fromdetection to functional insights. J Genet Genomics, 2024,51(2):111-132.

7)      Yuhan Zhang,Jun-Yan Kang, Mo-Fang Liu*, Ying Huang*. Diverse roles of biomolecularcondensation in eukaryotic translational regulation. RNA Biol,2023, 20(1): 893-907.

8)     Xin Wang, Di-Hang Lin, Yue Yan, An-HuiWang, Jiaoyang Liao, Qian Meng, Wen-Qing Yang, Heng Zuo, Min-Min Hua, FengjuanZhang, Hongwen Zhu, Hu Zhou, Rui He, Guangyong Li, Yue-QiuTan, Hui-Juan Shi, Lan-Tao Gou, Dangsheng Li, Ligang Wu, Yonggang Zheng,Xiang-Dong Fu, Jinsong Li, Rujuan Liu *, Guo-Hui Li* and Mo-FangLiu*. The PIWI-specific Insertion Module Helps LoadLonger piRNAs for Translational Activation Essential for Male Fertility. SCI CHINA Life Sci, 2023, 66(7): 1460-1481.

9)      Jun-Yan Kang, Ai Zhong, Ze Wen, Xinghai Yu, Yu Zhou, andMo-Fang Liu*. Polysome Profiling in Adult Mouse Testes. Bio Protoc, 2023, 13(11):e4686.

10)   Ming-Na Zhao, Ling-Fei Zhang, Zhen Sun, Li-HuaQiao, Tao Yang, Yi-Zhe Ren, Xian-Zhou Zhang, LeiWu, Wen-Li Qian, Qiao-Mei Guo, Wan-Xing Xu, Xue-QingWang, Fei Wu, Lin Wang, Yutong Gu*, Mo-Fang Liu*, andJia-Tao Lou*. A novel microRNA-182/Interleukin-8 regulatory axis controlsosteolytic bone metastasis of lung cancer. Cell Death Dis2023,14(5):298.

11)  Xin Wang,Anne Ramat, Martine Simonelig*, and Mo-Fang Liu*. Emerging roles andfunctional mechanisms of PIWI-interacting RNAs. Nat Rev Mol Cell Biol, 2023,24(2):123-141.

12)   Jun-Yan Kang, Ze Wen, Duo Pan, Yuhan Zhang, Qing Li, Ai Zhong,Xinghai Yu, Yi-Chen Wu, Yu Chen, Xiangzheng Zhang, Peng-Cheng Kou, Junlan Geng,Ying-Yi Wang, Min-Min Hua, Ruiting Zong, Biao Li, Hui-Juan Shi, Dangsheng Li,Xiang-Dong Fu, Jinsong Li, David L. Nelson, Xuejiang Guo, Yu Zhou, Lan-Tao Gou,Ying Huang*, and Mo-Fang Liu*. LLPS of FXR1 drives spermiogenesis byactivating translation of stored mRNAs. Science, 2022, 377(6607): eabj6647.

13)   Xin Wang, Yue-Qiu Tan*, Mo-Fang Liu*. Defective piRNA Processing andAzoospermia. N Engl J Med, 2022,386(17):1674-1675.

14)  Mao-ZhouZhao, Di-Hang Lin, Heng Zuo, Huan Wei, XinWang*, Lan-Tao Gou*, Mo-Fang Liu*. piRNA 3' uridylation facilitates the assembly of MIWI/piRNAcomplex for efficient target regulation in mouse male germ cells. CellRes, 2022,32(11):1030-1033.

15)  XinWang, Lan-Tao Gou*, Mo-Fang Liu*. Noncanonical Functions ofPIWIL1/piRNAs in animal male germ cells and human diseases. Biol Reprod, 2022, 107(1):101-108.

16)   Jiangshan Cong, Yihong Yang, Xin Wang, YingShen, Hui-Tao Qi, Chunyu Liu, Shuyan Tang, SixianWu, Shixiong Tian, Yiling Zhou, Xiaojin He, LingboWang*, Mo-Fang Liu*, Feng Zhang*. Deficiency of X-linkedTENT5D causes male infertility by disrupting the mRNA stability duringspermatogenesis. CellDiscov, 2022, 8(1):23.

17)   Feng Li, Peng Yuan, Ming Rao, Chun-Hui Jin, Wei Tang, Ye-FeiRong, Yun-Ping Hu, Fengjuan Zhang, Tao Wei, Qi Yin,Tingbo Liang, Ligang Wu, Jinsong Li, Dangsheng Li, Yingbin Liu, Wenhui Lou,Shuang Zhao*, and Mo-Fang Liu*. piRNA-independentFunction of PIWIL1 as a co-activator for Anaphase Promoting Complex/Cyclosometo Drive Pancreatic Cancer Metastasis. Nat Cell Biol, 2020,22(4):425-438.

18)   Xin Wang, Zhi-Tong Li, Yue Yan, Penghui Lin, Wei Tang, DanieleHasler, Rajyalakshmi Meduri, Ye Li, Min-Min Hua, Hui-Tao Qi, Di-Hang Lin,Hui-Juan Shi, Jingyi Hui, Jinsong Li, Dangsheng Li, Jian-Hua Yang, JinzhongLin, Gunter Meister, Utz Fischer, and Mo-Fang Liu*. LARP7-MediatedU6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice.Mol Cell, 2020,77(5):999-1013.

19)   Peng Dai, Xin Wang, and Mo-Fang Liu*. A dual role of thePIWI/piRNA machinery in regulating mRNAs during mouse spermiogenesis. Sci China Life Sci, 2020,63(3): 447-449. 

20)  Peng Dai, XinWang, Lan-Tao Gou, Zhi-Tong Li, Ze Wen, Zong-Gui Chen, Min-Min Hua, Ai Zhong,Lingbo Wang, Haiyang Su, Huida Wan, Kun Qian, Lujian Liao, Jinsong Li, BinTian, Dangsheng Li, Xiang-Dong Fu, Hui-Juan Shi*, Yu Zhou*, and Mo-Fang Liu*. A Translation-Activating Function of MIWI/piRNA duringMouse Spermiogenesis. Cell, 2019,179(7):1566-1581.

21)   Xiukun Wang, Jun-Yan Kang, Leixin Wei, XiaoganYang, Hongduo Sun, Suming Yang, Lei Lu, Meng Yan,MeizhuBai, Yanyan Chen, Juanjuan Long, Na Li, DangshengLi, Jing Huang, Ming Lei, Zhen Shao, Wen Yuan,ErweiZuo, Kehuan Lu*, Mo-Fang Liu*, Jinsong Li*. PHF7 is anovel histone H2A E3 ligase prior to histone-to-protamine exchange duringspermiogenesis. Development, 2019,146(13): dev175547.

22)  Lan-Tao Gou,Jun-Yan Kang, Peng Dai, Xin Wang,Feng Li, Shuang Zhao, Man Zhang, Min-Min Hua, Yi Lu, Yong Zhu, Zheng Li, HongChen, Li-Gang Wu, Dangsheng Li, Xiang-DongFu, Jingsong Li, Hui-Juan Shi*, Mo-FangLiu*.Ubiquitination-deficient Mutations in Human Piwi Cause Male Infertility byImpairing Histone-to-Protamine Exchange during Spermiogenesis. Cell,2017, 169(6):1090-1104.

23)   Ling-FeiZhang, Shuai Jiang*, Mo-Fang Liu*. MicroRNAregulation and analytical methods in cancer cell metabolism. Cell Mol Life Sci, 2017,74(16):2929-2941.

24)   Peng Yuan,Xiao-Hong He, Ye-Fei Rong, Jing Cao, Yong Li, Yun-Ping Hu, Yingbin Liu,Dangsheng Li, Wenhui Lou*, Mo-Fang Liu*. KRAS-NFκB-YY1-miR-489signaling axis controls pancreatic cancer metastasis. Cancer Res, 2017, 77(1):100-111.

25)   Xiao-HongHe, Wei Zhu, Peng Yuan, Shuai Jiang, Dangsheng Li, Hong-Wei Zhang, Mo-Fang Liu*. miR-155 downregulates ErbB2 andsuppresses ErbB2-induced malignant transformation of breast epithelial cells. Oncogene, 2016, 35(46):6015-6025.

26)  Ling-Fei Zhang, Jia-Tao Lou, Ming-HuaLu, Chunfang Gao, Shuang Zhao, Biao Li, Sheng Liang, Yong Li, DangshengLi, Mo-Fang Liu*. Suppressionof miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switchin hepatocellular carcinoma. EMBO J, 2015, 34(21):2671-2685.

27)  Peng Zhang, Jun-Yan Kang, Lan-Tao Gou, Jiajia Wang,Yuanchao Xue, Geir Skogerboe, Peng Dai, Da-Wei Huang, Runsheng Chen, Xiang-DongFu*, Mo-Fang Liu*,Shunmin He*. MIWI and piRNA-mediated cleavage of messengerRNAs in mouse testes. Cell Res, 2015, 25(2):193-207.

28)  Lin Wang, Ling-Fei Zhang, Jing Wu,Shu-Jun Xu, Yang-Yang Xu, Dangsheng Li, Jia-Tao Lou*, Mo-Fang Liu*. IL-1β-mediatedrepression of microRNA-101 is crucial for inflammation-promoted lungtumorigenesis. Cancer Res, 2014,74(17):4720-4730.

29)  Lan-Tao Gou, Peng Dai, Mo-Fang Liu*. Small non-coding RNAs andmale infertility. WIREs RNA, 2014,5(6):733-745.

30)  Lan-Tao Gou, Peng Dai, Jian-Hua Yang,Yuanchao Xue, Yun-Ping Hu, Yu Zhou, Jun-Yan Kang, XinWang, Hairi Li, Min-Min Hua, Shuang Zhao, Li-Gang Wu, Hui-JuanShi, Yong Li, Xiang-Dong Fu, Liang-Hu Qu, En-Duo Wang, Mo-Fang Liu*. Pachytene piRNAs instructmassive mRNA elimination during late spermiogenesis. Cell Res, 2014, 24(6):680-700.

31)  Song Hu, Wei Zhu, Ling-Fei Zhang, Ming Pei, Mo-Fang Liu*. MicroRNA-155 broadlyorchestrates inflammation-induced changes of microRNA expression in breastcancer. Cell Res, 2014, 24(2):254-257.

32)  Shuang Zhao, Lan-Tao Gou, Man Zhang, Li-Dong Zu, Min-Min Hua, Ye Hua,Hui-Juan Shi, Yong Li, Jin-Song Li, Dangsheng Li, En-Duo Wang*, Mo-Fang Liu*. piRNA-triggered MIWI ubiquitination and removal by APC/C in latespermatogenesis. Dev Cell, 2013, 24(1): 13-25.

33)  Shuai Jiang, Ling-Fei Zhang, Hong-WeiZhang, Song Hu, Ming-Hua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, En-DuoWang, Mo-Fang Liu*. A novelmiR-155/miR-143 cascade controls glycolysis by regulating hexokinase2 in breast cancer cells. EMBO J, 2012, 31(8):1985-1998.

34)  Meng Qiao, Li-Dong Zu, Xiao-Hong He,Ru-Ling Shen, Qing-Cheng Wang, Mo-FangLiu*. Onconase down-regulates microRNA expression through targetingmicroRNA precursors. Cell Res, 2012, 22(7):1199-1202.

35)  Shuai Jiang, Hong-Wei Zhang,Ming-Hua Lu, Xiao-Hong He, Yong Li, Hua Gu, Mo-Fang Liu*,En-Duo Wang. MicroRNA-155 functions as anoncomiR in breast cancer by targeting the suppressor of cytokine signaling-1gene. Cancer Res, 2010, 70(8): 3119-3127.

36)   Shuang Zhao, Mo-FangLiu*. Mechanisms of miRNA-mediated generegulation. Sci China C LifeSci, 2009, 52(12):1111-1116.

Mofang Liu*, Geeta Gupte, Siddhartha Roy, Rajiv P. Bandwar, SmitaS. Patel, Susan Garges S. Kinetics of transcription initiation atlacP1: Multiple roles of CRP. JBiol Chem, 2003,278(41): 39755-39761.