中国心胸血管麻醉学会围术期基础与转化医学分会委员兼秘书

中国非公立医疗机构协会重症医学专业委员会委员

作为负责人主持上海市自然科学基金、上海市卫健委面上项目、杨浦区卫健委临床研究专项、中华医学会麻醉学分会青年医师基金、上海市中西医结合学会“诺扬杯”青年医师科研基金等课题5项。授权国内专利2项，主译论著1部。作为PI/Sub-PI负责5项IIT临床研究项目。作为主要成员参与国自然以及上海市科委、卫健委、申康等项目10余项。研究成果已发表SCI论文近40篇，其中以第一/通讯作者（含共同）在Advanced science、Anesth Analg、Journal of Big Data，Annals of Medicine、Antioxidants等期刊发表 SCI 论文十余篇。

代表性论文（#一作，*通讯）：

1)   Juan Wei#, Feihong Lin#,Tian Jin#, Qian Yao，Sheng Wang，Di Feng，Xin Lv*，Wen He*. DynamicSOFA component scores-based deep learning for short to long-term mortalityprediction in sepsis survivors. Journal of Big Data. 2025;12:165.

2)   Chen Y#, Lin F#, Zhang T#,Xiao Z, Chen Y, Hua D, Wang Y, Wei J*, Jin T*, LvX*. Engineering Extracellular Vesicles Derived from3D Cultivation of BMSCs Enriched with HGF Ameliorate Sepsis-Induced LungEpithelial Barrier Damage. Advanced Science.2025;12(16):e2500637. 

3)   Deng H#, Zhou W#, Wei J#, Jin T, Chen Y, Zhu L, Yang H, Lv X. Bone marrowmesenchymal stem cell-derived exosomes alleviating sepsis-induced lung injury by inhibiting ferroptosis of macrophages. Int Immunopharmacol.2025;158:114789. 

4)   Juan Wei#, Xiaowei Zhang#,Keting Min#, Huanping Zhou, Xuan Shi, Huimin Deng, Wei Mo, HuafengWei, Yang Gu, Xin Lv*. Supraglottic Jet Oxygenation and Ventilation toMinimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under DeepSedation: A 3-Arm Randomized Controlled Trial. Anesthesia and Analgesia. 2024;138(2):456-464.

5)   Chen Song#, Liu Meiyun#, FengD, Lv Xin*, Wei Juan*. A Novel Strategy forPredicting 72-h Mortality After Admission in Patients With Polytrauma: A Studyon the Development and Validation of a Web-Based Calculator. Front Med.2022;9:799811.

6)   Zhang Yaodan#, Li Tingting#, Wei Juan#, Bao Rui, Lv Xin, Wang Jiafeng, Wu Jingxiang. Laryngeal mask airway combined with visual bronchial blocker versusdouble-lumen tube for lung isolation in video-assisted thoracoscopic surgery: aprotocol for a multicentre randomised controlled trial. BMJ Open.2025 Dec 30;15(12):e110539. 

7)   Gu Y, Zhang X, Li X, Min K, Deng H, Feng D, Zhou H, Wei J*, Lv X*.Evaluating lung ventilation via electrical impedance tomography during flexiblebronchoscopy with supraglottic jet ventilation: a prospective pilot study. J Anesth. 2025 Aug 27. doi: 10.1007/s00540-025-03568-w. 

8)   Juan Wei#, Guannan Chen#,Xuan Shi#, Huanping Zhou, Meiyun Liu, Yuanli Chen, Di Feng,Pengcheng Zhang, Lingmin Wu, Xin Lv*. Nrf2 activation protectsagainst intratracheal LPS induced mouse/murine acute respiratory distresssyndrome by regulating macrophage polarization. Biochem Biophys Res Commun. 2018;500(3):790-796.

9) Yang Gu#, XiangLi#, Qing Zhou, Huimin Deng, Faqiang Zhang, Juan Wei*,Xin Lv*. Uniportalvideo-assisted thoracic surgery versus open thoracotomy for chronic pain aftersurgery: a prospective cohort study. J Anesth.2024;38(4):525-536. 

10) 魏娟，邓惠民，吕欣. 术后肺部并发症围手术期风险因素及防治策略研究进展. 同济大学学报(医学版), 2021, 42(6):736-743.

11) Wang S#, Wei J#, Guo Y#, Xu Q#, Lv X, Yu Y*, Liu M*. Construction andvalidation of nomograms based on the log odds of positive lymph nodes topredict the prognosis of lung neuroendocrine tumors. Front. Immunol.2022;13:987881. 

12) Wang Y#, Wei J#, Deng H, Zheng L, Yang H*, Lv X*. The Role of Nrf2 inPulmonary Fibrosis: Molecular Mechanisms and Treatment Approaches. Antioxidants.2022;11(9):1685. 

13) Wei Mo#,Quanfu Li#, Huanping Zhou#, Xuan Shi, Hao Yang, ZhuoranXiao, Juan Wei*, Xin Lv*. Bibliometric analysis ofglobal research trends on pyroptosis in lung disease. Front Immunol.2022;13:978552. 

14) Deng H#, Wei J#, Min K#, Yang H, Wang S, Xiao Z, Liu M, Zheng L, Zhou H,Chen Y, Zhu W, Li Q*, Lv X*. Research trends inferroptosis since the origin of the concept: A bibliometric analysis. ClinExp Pharmacol Physiol. 2023;50(2):149-157.

15) Shi X#, Chen G#,Wei J#, Feng D, Chen Y, Zhou H, Liu M, Lv X*. UHPLC-Q-TOFMS-Based Metabolic Analysis for the Therapeutic Efficacy of "XuebijingInjection"against Sepsis-Induced Acute Lung Injury. EvidBased Complement Alternat Med, 2018;2018:8514619.

16) Shi X, Zhou H, Wei J, Mo W, LiQ, Lv X. The signaling pathways and therapeutic potential of itaconate toalleviate inflammation and oxidative stress in inflammatory diseases. Redox Biol.2022;58:102553.

17) Zheng L, Zhou W, Wu Y, Xu W, Hu S, Zhang Y,Xu H, Deng H, Chen Y, Wu L, Wei J, Feng D, Wang M, Zhou H, Li Q, Zhu L,Yang H, Lv X. Melatonin Alleviates Acute Respiratory Distress Syndrome byInhibiting Alveolar Macrophage NLRP3 Inflammasomes Through the ROS/HIF-1α/GLUT1Pathway. Lab Invest. 2023;103(12):100266.

18) Wu Y, Xu W, Zheng L, WangS, Wei J, Liu M, Zhou H, Li Q, Shi X, Lv X. 4-octyl itaconateameliorates alveolar macrophage pyroptosis against ARDS via rescuingmitochondrial dysfunction and suppressing the cGAS/STING pathway. Int Immunopharmacol. 2023;118:110104.

19) Liu M, Chen Y, Wang S, ZhouH, Feng D, Wei J, Shi X, Wu L, Zhang P, Yang H, Lv X. α-Ketoglutarate ModulatesMacrophage Polarization Through Regulation of PPARγ Transcription andmTORC1/p70S6K Pathway to Ameliorate ALI/ARDS. Shock.2020;53(1):103-113.