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同济大学附属同济医院放疗科主任，主任医师、教授、研究员，医学博士，博士后，博士生导师，省部级卫生拔尖人才。致力于从事肿瘤放化疗的临床与转化医学研究，熟练掌握常见肿瘤的综合治疗，擅长头颈部肿瘤、肺癌、消化道肿瘤及妇科肿瘤放疗为主的综合治疗，专业基础扎实。主持国家自然基金3项（青年基金1项，面上项目2项），省部级项目6项，为首授权国家发明专利3项，美国专利1项。以第一作者/通讯作者发表SCI论文60余篇，相关论文发表在《Int J Radiat Oncol Biol Phys》、《Radiotherapy and Oncology》、《Advanced Science》、《ACS Nano》《Cancer Letters》、《Oncogene》等权威期刊,以第一完成人或主要完成人获得省部级及厅级科技奖励5项，带教硕博士生20余人。
1) 国家自然科学基金面上项目，82073339、REV7招募Aly调控热休克蛋白HSP70家族影响食管癌放射敏感性的机制研究、2021/01-2024/12、56万元、在研、主持。
2) 国家自然科学基金面上项目，81773224、尿嘧啶转移酶TUT4修饰miR-132/212调控放射性食管损伤的机制研究、2018/01-2021/12、55万元、已结题、主持。
3) 国家自然科学基金青年基金，81402518、USP11去泛素化调控Nrf2/ARE通路对食管癌放射敏感性的影响及机制研究、2015/01-2017/12、23万元、已结题、主持。
1) Shizhen Ding, Huichao Liang, Jianlin Wang, Hong Zhu, Xiaofang Li, Qiu Zong, Xueqing Ma, Xujing Lu,Zhiqiang Sun, Wei Li, Judong Luo*.Aly as a Key Regulator of DNA Repair and Immune Evasion in Esophageal Squamous Cell Carcinoma Radioresistance.International Journal of Radiation Oncology Biology Physics. Online ahead of print(责任通讯作者，TOP期刊，Q1，IF=6.5)
2) Fuquan Zhang, Bingtao Huang, Yiming Xu, Guohong Cao, Mingjing Shen, Changmin Liu, Judong Luo* .MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non-Small Cell Lung Cancer. Advanced Science,2025 Apr;12(16):e2415814 (Q1，责任通讯作者，IF=14.1）
3) Xu B, Liu J, Fang M, Zhu H, Zhang Y, Zhang H, Lu X, Luo J*.Multicenter deep learning-based automatic delineation of CTV and PTV in uterine malignancy CT imaging.Radiother Oncol. 2025 Oct 19;214:111212. （责任通讯作者，Q1，放疗TOP期刊，IF=5.3）
4) Duan W, Liu H, Luo J*.Predicting Single-Cell Drug Sensitivity Utilizing Adaptive Weighted Features for Multi-Source Domain Adaptation.IEEE J Biomed Health Inform. 2025,29(8):6043-6054. (Q1，唯一通讯作者，IF=6.8）
5) Zhao M, Jin Y, Yan Z, He C, You W, Zhu Z, Wang R, Chen Y, Luo J*, Zhang Y, Yao Y.The splicing factor QKI inhibits metastasis by modulating alternative splicing of E-Syt2 in papillary thyroid carcinoma.Cancer Lett. 2024 Nov 1;604:217270. (Q1，共同通讯作者，IF=10.1）
6) Liu H, Zhang Y, Luo J*.Contrastive learning-based histopathological features infer molecular subtypes and clinical outcomes of breast cancer from unannotated whole slide images.Comput Biol Med. 2024;170:107997. (Q1，唯一通讯作者，IF=6.3）
7) Luo J, Gao Q, Wang M, Liu H, Zhu H.Single-cell and spatial transcriptome characterize coinhibitory cell-cell communications during histological progression of lung adenocarcinoma.Front Immunol. 2024 Oct 15;15:1430163. (Q1，第一作者，IF=5.9）
8) Li Q, Feng S, Yu Z, Wang Y, Tian L, Geng H, Guo C, Ning F, Luo J*, Liu C.Amelioration of Acute Radiation Dermatitis in Breast Cancer Patients by a Bioadhesive Barrier-Forming Gel (Episil): A Single-Center, Open, Parallel, Randomized, Phase I/II Controlled Trial.Clin Pharmacol Ther. 2024;115(5):1085-1091. (Q1，共同通讯作者，IF=5.5）
9) Yang Y, Xu B, Zhu H, Sun W, Liang A, Luo J.Combining CAR-T therapy with radiotherapy or not in refractory/relapsed diffuse large B-cell lymphoma: A comparative study.Clin Transl Radiat Oncol. 2025 Sep 2;55:101041. doi: 10.1016/j.ctro.2025.101041.（责任通讯作者）
10) Cai F, Li Y, Liu H, Luo J.Single-cell and Spatial Transcriptomic Analyses Implicate Formation of the Immunosuppressive Microenvironment during Breast Tumor Progression.J Immunol. 2024 Nov 1;213(9):1392-1401. （责任通讯作者）
11) Liu M, Sun Z, Tang Y, Zhang S, Luo J*. The Regulation of Exosome-Mediated miR-132-3p/miR-132-3p-UUU on Radiation-Induced Esophageal Injury. Radiat Res. 2023;200(2):151-161. (唯一通讯作者)
12) Wu J, Liu Y, Huang X, Cheng Y, Qian Z, Ni X, Chen S, Lin M, Luo J*. LncRNA DGCR5 Silencing Enhances the Radio-Sensitivity of Human Esophageal Squamous Cell Carcinoma via Negatively Regulating the Warburg Effect. Radiat Res. 2023;199(3):264-272. (责任通讯作者)
13) Tang Y, Yuan Q, Zhao C, Xu Y, Zhang Q, Wang L, Sun Z, Cao J, Luo J*, Jiao Y*.Targeting USP11 may alleviate radiation-induced pulmonary fibrosis by regulating endothelium tight junction.Int J Radiat Biol. 2022;98(1):30-40. (共同通讯作者)
14) Yiting Tang, Yayun Cui, Zengpeng Li, Zhuqing Jiao, Yong Zhang, Yan He, Guangxia Cheng, Qunyan Zhou, Wenjie Wang, Xifa Zhou, Judong Luo*,Shuyu Zhang*.Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells.Journal of Experimental & Clinical Cancer Research,35:7,2016(Q1，通讯作者，高引用论文，IF=12.8）
15) Judong Luo, Zengpeng Li, Hong Zhu, Chenying Wang, Weibin Zheng, Yan He, Jianyuan Song, Wenjie Wang, Xifa Zhou, Xujing Lu, Shuyu Zhang, Jianming Chen. A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells. International Journal of Biological Sciences, 12(6): 677-687,2016（Q1，IF=10）
16) Li Z#, Hao Q#, Luo J#, Xiong J#, Zhang S, Wang T, Bai L, Wang W, Chen M, Wang W, Gu L, Lv K, Chen J. USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2. Oncogene,35(22):2902-12,2016（Q1，共同第一作者，IF=7.3）
17) Wenjie Wang#,Judong Luo#,Wenjiong Sheng#,Jiao Xue,Ming Li,Jiang Ji,Pengfei Liu,Xueguang Zhang,Jianping Cao, Shuyu Zhang. Proteomic profiling of radiation-induced skin fibrosis in rats: targeting the ubiquitin-proteasome system. Int J Radiat Oncol Biol Phys,95(2):751-60,2016（Q1，共同第一作者，IF=6.5）
18) SH Chen, S Kang, J Luo*, R Zhou*.Charging nanoparticles: increased binding of Gd@C82(OH)22 derivatives to human MMP-9.Nanoscale;10(12):5667-5677，2018(Q1,通讯作者，IF=5.1）
19) Luo J, Zhu H, Jiang H, Cui Y, Wang M, Ni X, Ma C.The effects of aberrant expression of LncRNA DGCR5/miR-873-5p/TUSC3 in lung cancer cell progression.Cancer Med;7:3331-3341,2018（Q2,IF=3.1）
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