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刘卫青,精神病学副教授,硕士生导师,于2012年在中南大学湘雅医学院获临床医学博士学位,于2018.11-2021.1在日本理化学研究所(RIKEN)脑科学中心进行博士后研究(JSPS研究员),现任职于上海市浦东新区精神卫生中心科教科副科长、GCP机构办主任。目前承担的学术任职包括:中华医学会行为医学分会青年委员、中华医学会心身医学分会成瘾医学组委员、中华医学会行为医学分会睡眠医学组委员、中国医师协会精神科医师分会非药物治疗工作委员会委员、中国睡眠研究会睡眠与心理卫生专业委员会委员、《国际精神病学杂志》青年编委、《四川精神医学》杂志第八届编委。研究方向为精神分裂症的分子神经机制及物理治疗,长期致力于遗传和环境因素通过影响脑发育和应激内稳态导致精神分裂症发病的机制研究。分别在临床患者和动物模型中探索疾病发生和治疗过程中的分子神经机制,并在此基础上寻找新的干预靶标。曾主持国家自然科学基金1项,省厅级课题3项,发表科研论文35篇。

1. 国家自然科学基金项目, 81860253,锂盐早期干预对精神分裂症发病的阻断效果及其机制的初步探讨,2019/1-2022/12,35万元,已结题,主持。
2. 浦东新区科技发展基金事业单位民生科研专项(医疗卫生)项目,PKJ2025-Y24,基于精神分裂症类脑器官探索GAD1基因eQTL调控兴奋-抑制平衡的机制,2025.8.1-2027.7.30,30万元,在研,主持。
3. 上海市浦东新区卫健委学科建设项目,PWZzk2022-19,“精神障碍物理诊疗重点专科”,2022.12-2026.11,40万元,在研,主持。
4. 上海市浦东新区“卫生系统学科带头人培养计划”,PWRd2021-06,“皮层内抑制”作为精神分裂症认知缺陷评估与疗效预测的客观生物标记研究;2022.1-2024.12,30万元,已结题,主持。
5. 浦东新区科技发展基金事业单位民生科研专项(医疗卫生)项目,PKJ2021-Y17,发育期阈下经颅磁刺激对NMDA受体缺陷诱导精神分裂症小鼠模型的逆转作用,2021.12-2023.11,30万元,已结题,主持。
6. 国家自然科学基金青年项目,3170080806,染色体1q21.1区段候选基因在中国汉族人群中影响精神分裂症的遗传机理和作用机制研究,2018/01-2020/12,25万元,已结题,参与。
1. 国家自然科学基金项目, 81860253,锂盐早期干预对精神分裂症发病的阻断效果及其机制的初步探讨,2019/1-2022/12,35万元,已结题,主持。
2. 浦东新区科技发展基金事业单位民生科研专项(医疗卫生)项目,PKJ2025-Y24,基于精神分裂症类脑器官探索GAD1基因eQTL调控兴奋-抑制平衡的机制,2025.8.1-2027.7.30,30万元,在研,主持。
3. 上海市浦东新区卫健委学科建设项目,PWZzk2022-19,“精神障碍物理诊疗重点专科”,2022.12-2026.11,40万元,在研,主持。
4. 上海市浦东新区“卫生系统学科带头人培养计划”,PWRd2021-06,“皮层内抑制”作为精神分裂症认知缺陷评估与疗效预测的客观生物标记研究;2022.1-2024.12,30万元,已结题,主持。
5. 浦东新区科技发展基金事业单位民生科研专项(医疗卫生)项目,PKJ2021-Y17,发育期阈下经颅磁刺激对NMDA受体缺陷诱导精神分裂症小鼠模型的逆转作用,2021.12-2023.11,30万元,已结题,主持。
(1) Zhu A Z Zheng, Wei Wang, Fu M Yang, Wei Q Liu(*), Guo S Han(*). Human foetal brain self-organises intolong-term expanding organoids, Biomater Transl. 2024 Nov 15;5(4):451-453.
(2) Linlin Zhao, Liwen Tan, Weiqing Liu, Sijie Zhang, AijunLiao, Liu Yuan, Ying He, Xiaogang Chen, Zongchang Li. The Causal RelationshipsBetween Inflammatory Proteins, Brain Structure, and Psychiatric Disorders: ATwo-Step Mendelian Randomization Analysis, Schizophrenia Bulletin. 2024 Dec 9 :sbae208.
(3) Minghuan Zhu, Yifan Xu, Qi Zhang, Xiaoyan Cheng, LeiZhang, Fengzhi Tao, Jiali Shi, Xingjia Zhu, Zhihui Wang, Xudong Zhao &Weiqing Liu(*). Reduction of intracortical inhibition (ICI)correlates with cognitive performance and psychopathology symptoms inschizophrenia, Schizophrenia (2024) 10:78
(4) Wang Yujue; Fan Lejia, He Ying, Yuan Liu, Li Zongchang, ZhengWenxiao, Tang Jinsong, Li Chunwang, Jin Ke, Liu Weiqing, Xiaogang Chen, Lijun Ouyang, Xiaoqian Ma. Compensatorythickening of cortical thickness in early stage of schizophrenia, CerebralCortex 2024: 34(6), June 2024, bhae255.
(5) Sheng Zhihao, Liu Qidong, Lin Rong, Zhao Yan, Liu Weiqing, Xu Zhendong, Liu Zhiqiang.Potential CSF biomarkers of postpartum depression following delivery via caesariansection. J Affect Disord. 2023 Dec 1;342:177-181.
(6) Zhang L, Zhao N, Zhu M, Tang M, Liu W, Hong W.Adverse childhood experiences in patients with schizophrenia: related factorsand clinical implications. Front Psychiatry. 2023;14:1247063.
(7) Wenjuan Hong, Qiang Wang, Qinghong Hou, Nan Zhao, RuolingWang, Yan Bai, Chengping Hu, Weiqing Liu(*). Home quarantine duringCOVID-19 blunted childhood trauma-related psychiatric symptoms in Chinesecollege students, Front Public Health. 2023: 11: 1073141.
(8) Qiang Wang, Lingyun Zeng, Wenjuan Hong, Mingying Luo, NanZhao, Xiaofen Hu, Meili Shi, Jing Qiu, Yanmin Shen, Xiuju Teng, Haiying Min(*),Weiqing Liu(*). InflammatoryCytokines Changed in Patients With Depression Before and After RepetitiveTranscranial Magnetic Stimulation Treatment. Frontiers in Psychiatry, 2022 Jun2;13:925007.
(9) Li HJ, Zhang C, Hui L, Zhou DS, Li Y, Zhang CY, Wang C,Wang L, Li W, Yang Y, Qu N, Tang J, He Y, Zhou J, Yang Z, Li X, Cai J, Yang L,Chen J, Fan W, Tang W, Tang W, Jia QF, LiuW, Zhuo C, Song X, Liu F, Bai Y, Zhong BL, Zhang SF, Chen J, Xia B, Lv L,Liu Z, Hu S, Li XY, Liu JW, Cai X, Yao YG, Zhang Y, Yan H, Chang S, Zhao JP,Yue WH, Luo XJ, Chen X, Xiao X, Fang Y, Li M; GeseDNA Research Team. Novel Risk Loci Associated With Genetic Riskfor Bipolar Disorder Among Han Chinese Individuals[J]. JAMA Psychiatry, 2021Mar 1;78(3):320-330.
(10) Tong J, Zhang J, Jin Y, Liu W, Wang H, Huang Y,Shi D, Zhu M, Zhu N, Zhang T, Sun X. Impact of Repetitive Transcranial MagneticStimulation (rTMS) on Theory of Mind and Executive Function in Major DepressiveDisorder and Its Correlation with Brain-Derived Neurotrophic Factor (BDNF): ARandomized, Double-Blind, Sham-Controlled Trial. Brain Sci. 2021 Jun9;11(6):765. doi: 10.3390/brainsci11060765.
(11) Zhao S*, LiuW*, Feng C, Zhang X, Cai W, LuoM. Effect and Molecular Mechanisms of Collateral Vessel Growth Mediated byActivation of Transient Receptor Potential Vanilloid Type 1[J]. Journal ofVascular Research, 2020;57(4):185-194.
(12) Lijuan Zhao, Hong Chang, Dong-Sheng Zhou, Jun Cai,Weixing Fan, Wei Tang, Wenxin Tang, Xingxing Li, Weiqing Liu, Fang Liu, Yuanfang He, Yan Bai, Yan Sun, Jiapei Dai,Lingyi Li, Xiao Xiao, Chen Zhang, Ming Li. Replicated associations of FADS1,MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinesepopulation. Transl Psychiatry. 2018 Dec 7;8(1):270.
(13) Liu W*, Wang F*, Zhao M, Fan Y, Cai W,Luo M.. The Neuropeptide Secretoneurin Exerts a Direct Effect on ArteriogenesisIn Vivo and In Vitro . The Anatomical Record. 2018 Nov;301(11):1917-1927.
(14) Wang L*, Liu W*, Li X, Xiao X, Li L, Liu F, HeY, Bai Y, Chang H, Zhou DS, Li M. Further Evidence of an Association betweenNCAN rs1064395 and Bipolar Disorder. Mol Neuropsychiatry. Jun 2018;4(1):30-34.
(15) Wang D, Li Z, LiuW, Zhou J, Ma X, Tang J, Chen X. Differential mitochondrial DNA copy number in three moodstates of bipolar disorder. BMC Psychiatry. 2018 May 25;18(1):149.
(16) Liu W, Liu F, Xu X, BaiY. Replicated association between the European GWAS locus rs10503253 at CSMD1and schizophrenia in Asian population. Neuroscience letters. 2017 Apr;647:122-8.
(17) Liu W, Wang X, Hong W,Wang D, Chen X. Establishment of a schizophrenic animal model through chronicadministration of MK-801 in infancy and social isolation in childhood. Infantbehavior & development. 2017;46:135-43.
(18) Liu W, Wang D, Hong W, YuY, Tang J, Wang J, et al. Psychotomimetic effects of different doses of MK-801and the underlying mechanisms in a selective memory impairment model.Behavioural brain research. 2017;320:517-25.
(19) Wang J, Cao H, Liao Y, Liu W, Tan L, Tang Y, et al. Three dysconnectivity patterns in treatment-resistantschizophrenia patients and their unaffected siblings. NeuroImage Clinical.2015;8:95-103.
(20) Ma L, Tang J, Wang D, Zhang W, Liu W, Wang D, et al. Evaluating risk loci for schizophreniadistilled from genome-wide association studies in Han Chinese from CentralChina. Molecular psychiatry. 2013;18(6):638-9.
(21) Chen X*, Liu W*, Wang L, Tang J, Wang X, Han X,et al. Psychosocial functioning and cognitive deficits are not associated withmembrane-bound catechol-O-methyltransferase deoxyribonucleic acid methylationin siblings of patients with schizophrenia. The Journal of nervous and mentaldisease. 2012;200(11):941-5.
(22) Chen L, Chen X, LiuW, Wang Q, Jiang T, Wang J, et al. White matter microstructuralabnormalities in patients with late-onset schizophrenia identified by avoxel-based diffusion tensor imaging. Psychiatry research. 2013;212(3):201-7.
(23) Tang J, Liao Y, Zhou B, Tan C, Liu W, Wang D, et al. Decrease in temporal gyrus gray matter volumein first-episode, early onset schizophrenia: an MRI study. PloS one.2012;7(7):e40247.
(24) Han H, He X, Tang J, LiuW, Liu K, Zhang J, et al. The C(-1562)T polymorphism of matrixmetalloproteinase-9 gene is associated with schizophrenia in China. Psychiatryresearch. 2011;190(1):163-4.
(25) Jiang S, Zhou B, Liao Y, Liu W, Tan C, Chen X, et al. [Primary study of resting statefunctional magnetic resonance imaging in early onset schizophrenia using ReHo].Zhong nan da xue xue bao Yi xue ban = Journal of Central South UniversityMedical sciences. 2010;35(9):947-51.
五、发表中文论文
1. 盘易鑫,罗兰,朱明,邱佳怡,朱明环,刘芳,刘卫青*. 青春期低强度iTBS对小清蛋白神经元特异性Grin1敲除小鼠精神分裂症样行为的影响. 国际精神病学杂志,2025. 52(1):38-42.
2. 刘卫青, 徐一凡,马晓倩, 贺莹, 陈晓岗. 不同类型童年期应激与精神分裂症症状谱的相关性研究. 国际精神病学杂志,2024. 51(2):366-371.
3. 洪文娟, 李密, 侯庆红, 罗明英, 胡承平, 刘卫青. 大学生童年期社会挫败问卷的编制及其信效度分析. 国际精神病学杂志,2022. 49(6):988-992.
4. 许毅,李达,谭立文,刘卫青,石川,傅建明,安建雄. 重复经颅磁刺激治疗专家共识.转化医学杂志,2018,7(1):4-9.
5. 刘卫青,谭立文,陈晓岗. 表观遗传学在精神疾病研究中的现状和展望. 中华精神科杂志,2010,43(3): 187-190.
6. 刘卫青,谭立文. 精神分裂症易感基因与认知缺陷及阴性症状的相关性.国际精神病学杂志, 2008,35(4):197-203.
7. 刘卫青,万凤,谭立文. 精神疾病患者遭受社会歧视的现状及其原因与对策分析. 医学与哲学, 2008,29(1):69-71.
8. 黄若华,李绍波,刘卫青,谭立文. 精神分裂症患者Ⅰ级亲属的STROOP执行功能研究. 中国行为医学科学, 2008,17(8)2: 722-723.
9. 于文娟,朱浩,万凤,刘卫青,谭立文. 首发精神分裂症患者及其正常一级亲属血脂和肥胖的研究. 神经疾病与精神卫生,2010,10(6):546-548.
10. 唐劲松,陈晓岗,周炳,廖艳辉,刘卫青等.基于功能磁共振成像的早发精神分裂症默认网络研究.临床精神医学杂志,2010,20(5):289-292.
11. 蒋少艾,周炳, 廖艳辉, 刘卫青等. 基于fMRI的早发精神分裂症患者静息态脑活动的局部一致性初步研究.中南大学学报(医学版) 2010, 35(9) 947-950.
12. 向熙,刘卫青,于艺,王栋,陈晓岗. 急慢性注射地卓西平马来酸盐对小鼠额叶microRNA-181b表达的影响. 中国神经精神疾病杂志. 2012, 38(6) 346-349
13. 刘卫青,唐劲松,陈晓岗. 精神分裂症发病的二阶段损害机制. 国际精神病学杂志, 2013,40(2):89-91.
14. 王栋, 刘卫青, 陈晓岗. 不同剂量地卓西平马来酸盐诱导雄性大鼠再认记忆缺陷的比较. 中华行为医学与脑科学杂志 ISTIC, 2013, 22(6). 481-483
15. 万凤,于文娟,王利锋,刘卫青,谭立文. 精神分裂症患者未患病一级亲属的认知功能研究. 精神医学杂志,2014,(06):405-408.
16. 许秀峰,刘卫青. 精神分裂症后抑郁的原因与治疗——读者来信[J]. 临床精神医学杂志,2016,(03):215-216.

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