团队包含PI一人、助理研究员2人，博士后4人，研究生 10人。

课题组目前在研项目：包含基金委重点项目1项、面上项目1项、科技部重点研发计划（骨干）1项；团队成员主持基金委青年项目4人项，上海市扬帆计划2项。

1.    2025-11-2028.10 国家重点研发计划“生育健康及妇女儿童健康保障”重点专项“围着床其母体蜕膜与胚胎胚外组织互作的机制研究”2025YFC2708002，70万元，进行中

2.    2024.01- 2027.12，国家自然科学基金联合创新重点项目U23A20405，滋养细胞低免疫原性分化障碍诱导胚胎抗原特异CD8+T 细胞异常活化致妊娠失败的分子机制，260.00万元 进行中

3.    2023.01-2026.12国家自然科学基金面上项目82271713，蜕膜基质细胞铁死亡信号异常致早期妊娠失败的分子机制，52万元，主持，进行中

4.    2022-01-2024.12 国家重点研发计划（战略性科技创新合作，2021YFE0206500）益母草碱对子宫内膜异位症内膜功能的重塑作用 160万元 结题

5.     2020.1-2023-12 国家自然科学基金面上项目31970859，Galectin-9/CD44介导的滋养细胞-蜕膜巨噬细胞异常对话诱导胎盘血管重塑不良致子痫前期的分子机制，59万元，主持 结题

6.     2017.1-2021.12国家自然科学基金重点项目81630036 胎盘发育不良与蜕膜化障碍致早期妊娠失败的分子机制及其干预研究                  （项目负责人）       275万  结题

Selected Publication

1）  Peng Lijin#, Zhao Weijie#, Xu Chunfang#, Li Yue#, Jiani Guo, Zhou Taotao,Chiu Philip, Wu Huimei, Qingyu Wu, Wei Yanxing *, Gao Shaorong*, Du Meirong*. BHLHE40cooperates with GATA2/3 to control human syncytiotrophoblast lineagedifferentiation。DOI: 10.1002/advs.71652 (IF=14.1）

2）  Hu Xianyang Hu#, Huang Xixi，Yin Tingxuan#，Yu Hailin，Liu Lu*，and Du Meirong*. Therapeutic Efficacy of Cyclosporine A in Recurrent SpontaneousAbortion: A Meta-Analysis and Network Meta-Analysis Incorporating Chinese andEnglish Language Studies. eClinicalMedicine 2025;87: 103442 （IF=10)

3)   HuangXX#，YinTX#，YuM#，ZhuGH#，HuXY，YuHL，ZhaoWJ，ChenJJ，DuJY，WuQY，ZhangWei*，LiuLu*，DuMR*. Decidualization-Associated Recruitment ofCytotoxic Memory CD8+T Cells to the Maternal-Fetal Interface for Immune Defense.Mucosal Immunology.  https://doi.org/10.1016/j.mucimm.2024.12.007（IF：8.2）

4)  Chen JJ#,Yin TX#, Hu XY, Chang LY, Sang YF, Xu L, Zhao WJ, Liu L, Xu CF, Lin YK, Li Y, WuQY, Li DJ*, Li YH*, and Du MR*. CD36-mediated arachidonic acid influxfrom decidual stromal cells increases inflammatory macrophages in miscarriage.Cell Reports, 43，114881（IF：7.5）

5) TangZ#, Zhang XC#, Meng SY, Yi X, Liu YH, Wu KF, Li Y, Peng SJ, Guo H, Du MR*,Zhu YZ*, Wang XL*. Cell membrane camouflaged and ROS responsive nanosomes fortargeted endometriosis therapy via reversing inflammatory, low-autophagy, andimmunotolerant microenvironment. Chemical Engineering Journal. Volume 493, 1August 2024,152697 （IF：13.4）

6) Xu CF #，ZhaoWJ#，Peng LJ， Yin TX， Guo JN， Li Y， Liu L， YangJY， Xu CJ*， Du MR*. PRDM14 extinction enables theinitiation of trophoblast stem cell formation. Cellular and Molecular LifeSciences. DOI: 10.1007/s00018-024-05237-9 (IF: 6.2)

7)       Li YH#，Sang YF#，ChangYJ#，Xu ChF#，Lin YK，Zhang Y，Chiu Philip,Yeung William, Zhou HS Dong NZ, Xu L, Chen JJ, Zhao WJ, Liu Lu, Yu D, Zang XX,Ye JF, Yang JY*, Wu QY, Li DJ*, Wu LG*, Du MR*. A Galectin-9-DrivenCD11chigh Decidual Macrophage Subset Suppresses Uterine VascularRemodeling in Preeclampsia. Circulation, 2024;149:1670–1688.（IF：38.5）

8)       Yin TX,Li XY, Li YY, Zang XX，Liu L#, Du MR#.Macrophage plasticity and function incancer and pregnancy. Front Immunol. 2024 Jan 11;14:1333549.  （IF：7.8）

9)      Cui LY,Xu Feng, Xu ChF, Ding Y, Wang SC*, Du MR*. Circadian gene Rev-erbαinfluenced by sleep conduces to pregnancy by promoting endometrialdecidualization via IL-6-PR-C/EBPβ axis. Journal of Biomedical Science (2022)29:101.（IF：11）

10)       Li YY#,Lin YK#, Li Y, Liu XH, Li DJ, Wang XL, Wang L, Zhu YZ*, Yu M*, Du MR*.SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediatedDifferentiation and Function of CD4+CD25+ Regulatory T Cells. InternationalJournal of Biological Sciences. 2022 Feb 21;18(5):1961-1973.（IF:9.2）

11)       Li MD#,Sun FR#, Xu YY#, Chen LT, Chen Chq, Cui LY, Qian JF, Li DJ , Wang SC*，Du MR*.Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells andpromoted pregnancy maintenance via CD132. Cell Death & Disease. 2022 May12;13(5):454（IF:9.0）

12)       Li YH, Zhang D, Du MR*. Advances And Challenges Of Mesenchymal Stem Cells For Pregnancy Related Diseases. Cell Mol Immunol. 2021;18(8):2075-2077.  (IF:22.096)

13)   Jin XL#, Cui LY#, Zhao WJ, Li XY, Liu L, Li YH, Fu Q, Li DJ, Yu M, Du MR*. Decidualization-derived cAMP regulates phenotypical and functional conversion of decidual NK cells from CD56dimCD16- NK cells. Cell Mol Immunol. 2021,18(6):1596-1598.  (IF:22.096)

14)   Zheng J#, Li YH#, Sang YF#, Xu L, Li DJ, Du MR*. Pigment epithelium-derived factor (PEDF), a novel decidual naturalkiller cells-derived factor, protects decidual stromal cells viaanti-inflammation and anti-apoptosis in early pregnancy. Hum Reprod.35(7):1537-1552. (2020 IF :6.918)

15)   Wang SC#, Sun FR#, Li MD, Qian JF, Chen CQ, Wang MY, Zang XX, LiDJ, Min Yu*, Du MR*.The appropriate frequency and function of decidual Tim-3+CTLA-4+CD8+Tcells are important in maintaining normal pregnancy. Cell Death & Disease.Cell Death & Disease. 2019，10(6):407（IF2019：6.304）