同济大学
导师风采
白钟飞
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个人信息

Personal Information

  • 副主任技师
  • 导师类别:硕士生导师
  • 性别: 男
  • 学历:博士研究生
  • 学位:博士

联系方式

Contact Information

  • 所属院系:医学院
  • 所属专业: 康复医学与理疗学
  • 邮箱 : zhongfei@tongji.edu.cn
  • 工作电话 : -

个人简介

Personal Profile

白钟飞,博士,副主任治疗师,作业治疗师长,神经调控负责人,同济大学硕士生导师,上海市“扬帆计划”获得者,中国康复医学会“优秀青年治疗师”,同济大学医学院物理治疗本科授课教师和在职研究生授课教师。在Brain Stimulation, JNER等期刊发表SCI论文20余篇,获中国康复医学科技奖励2项,上海市卫健委科普奖励1项,主持各级科研课题8项,主要研究方向为脑卒中上肢功能康复的中枢机制,非侵入式脑刺激。

researchgate主页:https://www.researchgate.net/profile/Zhongfei-Bai/research

Google Scholar主页:https://scholar.google.com/citations?user=aq8qpCoAAAAJ&hl=en


  • 研究方向Research Directions
神经康复治疗研究,神经调控的临床与机制研究
2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行2. 机电结构优化与控制 研究内容:在对机电结构进行分析和优化的基础上,运用控制理论进行结构参数的调整,使结构性能满足设计要求。1. 仿生结构材料拓扑优化设计, 仿生机械设计 研究内容:以仿生结构为研究对象,运用连续体结构拓扑优化设计理论和方法,对多相仿生结构(机构)材料进行整体布局设计。 整体布局设计。
团队展示

经颅磁刺激(TMS)是一种无创的脑刺激技术。它是基于法拉第电磁感应原理,TMS刺激线圈产生的变化磁场可穿过颅骨,在特定大脑皮层形成感应电场,改变神经元静息膜电位,达到刺激中枢神经的目的。研究团队围绕中枢神经系统疾病的重大问题,开展临床治疗和科学研究研究。白钟飞博士所带领的神经调控室现有经颅磁刺激(依瑞德NS3000)5台,经颅磁刺激(Magventure,丹麦)2台,肌电图(Dantec KEYPOINT,美国)1套,可开展基于MEP的单脉冲、成对脉冲技术对运动系统皮质脊髓束兴奋性的检测。在神经导航系统(2套)的支持下,还可对大脑皮层进行精准靶向刺激,空间误差<2mm。此外,团队还掌握外部控制TMS的试验技术,可实现任务态在线(online)和离线(offline)状态下的精准TMS刺激,用于研究特定脑区与特定任务的关系。

TMS与EEG结合的技术(TMS-EEG)可记录TMS诱发电位(TMS-evoked potentials, TEPs),是研究大脑神经活动新策略。团队对TMS-EEG在脑卒中的研究有较为丰富的研究基础和经验,已在养志康复医院建成完整试验平台。

近红外光谱(fNIRS)技术是利用含氧血红蛋白(HbO)和脱氧血红蛋白(HbR)对近红外光子的不同吸收系数 ,进而获得HbO和HbR的浓度变化,可间接反应脑区皮层神经的活动状态。团队现有54通道近红外一台(FUJIFILM ,日本),并搭配正版E-Prime3软件,可对多个脑区同步采集静息态和任务态下fNIRS信号,也可实现多人的超扫描。 

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发表论文

[1]        ZhangJJ, Bai Z, Ganesan B, Fong KNK.Chapter 15 - Neurotechnology for Poststroke Motor Rehabilitation. In: Tong RKY,Ganesan B, editors. Digital Technology in Public Health and RehabilitationCare: Academic Press; 2025, p. 239-251.

 [2]        Zhu F, Xu X, Jin M, Chen J, Feng X, WangJ, Yu D, Wang R, Lian Y, Huai B, Lou X, Shi X, He T, Lu J, Zhang JJ, Bai Z. Priming Transcranial DirectCurrent Stimulation for Improving Hemiparetic Upper Limb in Patients withSubacute Stroke: Study Protocol for a Randomised Controlled Trial. BMJ open,2024, 14(2): e079372.

[3]        Zhang JJ, Zhang BB, Bai Z, Fong KNK. A Comparative Study of Simulated Electric Fieldsof Transcranial Magnetic Stimulation Targeting Different Cortical MotorRegions. 2024, n/a(n/a).

[4]        Zhang JJ, Sui Y, Sack AT, Bai Z, Kwong PWH, Sanchez Vidana DI,Xiong L, Fong KNK. Theta Burst Stimulation for Enhancing Upper Extremity MotorFunctions after Stroke: A Systematic Review of Clinical and MechanisticEvidence. Reviews in the neurosciences, 2024.

[5]        Zhang JJ, Bai Z, Vidana DIS, Cousijn J, Fong KNK. Computational Simulation ofTranscranial Magnetic Stimulation-Induced Electric Fields in the DorsolateralPrefrontal Cortex of Heavy Cannabis Using Individuals. Asian journal ofpsychiatry, 2024: 103963.

[6]        Zhang JJ, Bai Z, Mehler DM, Kwong PW, Lam TL, Fong KN. ModulatingLow-Frequency Oscillations in Post-Stroke Brains Using Priming IntermittentTheta Burst Stimulation. Eur J Phys Rehabil Med, 2024.

[7]        Zhang JJ, Bai Z, Fong KNK. Resting-State Cortical ElectroencephalogramRhythms and Network in Patients after Chronic Stroke. Journal ofNeuroEngineering and Rehabilitation, 2024, 21(1): 32.

[8]        Zhang JJ, Bai Z, Fong KNK. Methodological Considerations of PrimingRepetitive Transcranial Magnetic Stimulation Protocols in Clinical Populations.General Psychiatry, 2024, 37(1): e101237.

[9]        BaiZ, Zhang JJ, Ti ECH, Jin M, Zhu F, Liang S, Zhang J, Yang Y, Hong R, Lan D,Tong RKY, Ziemann U, Jin L. Loss of Stimulation Intensity- and CorticalActivity-Dependent Tms-Evoked Reactivity in Poststroke Primary Motor Cortex.Brain Stimulation: Basic, Translational, and Clinical Research inNeuromodulation, 2024, 17(6): 1286-1289.

[10]      Zhang H, Ji H, Yu J, Li J, Jin L, Liu L, Bai Z, Ye C. Subject-Independent EegClassification Based on a Hybrid Neural Network. Front Neurosci, 2023, 17.

[11]      Li H, Ji H, Yu J, Li J, Jin L, Liu L, Bai Z, Ye C. A Sequential LearningModel with Gnn for Eeg-Emg-Based Stroke Rehabilitation Bci. Front Neurosci,2023, 17: 1125230.

[12]      Feng Y, Zhang JJ, Zhu J, Tan X, Huang S, Bai Z, Yin Y. Does Intermittent ThetaBurst Stimulation Improve Working Memory Capacity? A Randomized ControlledCross-over Experiment. Behavioural brain research, 2023, 436: 114086.

[13]      BaiZ, Zhu F, Lou X, Zhang JJ, Jin M, Qin W, Tang C, Li J, Lu J, Lin J, Jin L,Qi Q, Fong KNK. Considerable Effects of Lateralization and Aging inIntracortical Excitation and Inhibition. 2023, 17.

[14]      BaiZ, Zhang JJ, Fong KNK. Intracortical and Intercortical Networks in Patientsafter Stroke: A Concurrent Tms-Eeg Study. Journal of NeuroEngineering andRehabilitation, 2023, 20(1): 100.

[15]      BaiZ, Zhang JJ, Fong KNK. Immediate Effects of Intermittent Theta BurstStimulation on Primary Motor Cortex in Stroke Patients: A Concurrent Tms-EegStudy. IEEE transactions on neural systems and rehabilitation engineering : apublication of the IEEE Engineering in Medicine and Biology Society, 2023, 31:2758-2766.

[16]      Zhang JJ, Bai Z, Fong KNK. Priming Intermittent Theta Burst Stimulation forHemiparetic Upper Limb after Stroke: A Randomized Controlled Trial. Stroke,2022, 53(7): 2171-2181.

[17]      Xia W, Dai R, Xu X, Huai B, Bai Z, Zhang J, Jin M, Niu W. CorticalMapping of Active and Passive Upper Limb Training in Stroke Patients andHealthy People: A Functional near-Infrared Spectroscopy Study. Brain research,2022, 1788: 147935.

[18]      Wei Y, Li J, Ji H, Jin L, Liu L, Bai Z, Ye C. A Semi-SupervisedProgressive Learning Algorithm for Brain-Computer Interface. IEEE transactionson neural systems and rehabilitation engineering : a publication of the IEEEEngineering in Medicine and Biology Society, 2022, 30: 2067-2076.

[19]      Liu F, Chen C, Hong W, Bai Z, Wang S, Lu H, Lin Q, Zhao Z,Tang C. Selectively Disrupted Sensorimotor Circuits in Chronic Stroke with HandDysfunction. CNS neuroscience & therapeutics, 2022, 28(5): 677-689.

[20]      Liu F, Chen C, Bai Z, Hong W, Wang S, Tang C. Specific Subsystems of the InferiorParietal Lobule Are Associated with Hand Dysfunction Following Stroke: ACross-Sectional Resting-State Fmri Study. CNS neuroscience & therapeutics,2022, 28(12): 2116-2128.

[21]      Jin M, Pei J, Bai Z, Zhang J, He T, Xu X, Zhu F, Yu D, Zhang Z. Effects ofVirtual Reality in Improving Upper Extremity Function after Stroke: ASystematic Review and Meta-Analysis of Randomized Controlled Trials. ClinRehabil, 2022, 36(5): 573-596.

[22]      BaiZ, Zhang J, Tang C, Wang L, Xia W, Qi Q, Lu J, Fang Y, Fong KNK, Niu W.Return-to-Work Predictions for Chinese Patients with Occupational UpperExtremity Injury: A Prospective Cohort Study. Frontiers in medicine, 2022, 9:805230.

[23]      BaiZ, Zhang J, Fong KNK. Effects of Transcranial Magnetic Stimulation inModulating Cortical Excitability in Patients with Stroke: A Systematic Reviewand Meta-Analysis. Journal of NeuroEngineering and Rehabilitation, 2022, 19(1):24.

[24]      Xia W, Bai Z, Dai R, Zhang J, Lu J, Niu W. The Effects of SensoryRe-Education on Hand Function Recovery after Peripheral Nerve Repair: ASystematic Review. NeuroRehabilitation, 2021, Preprint: 1-12.

[25]      Wu J, Cheng H, Zhang J, Bai Z, Cai S. The Modulatory Effects ofBilateral Arm Training (Bat) on the Brain in Stroke Patients: A SystematicReview. Neurological sciences : official journal of the Italian NeurologicalSociety and of the Italian Society of Clinical Neurophysiology, 2021, 42(2):501-511.

[26]      BaiZ, Zhang J, Fong KNK. Intermittent Theta Burst Stimulation to the PrimaryMotor Cortex Reduces Cortical Inhibition: A Tms-Eeg Study. Brain Sciences,2021, 11(9): 1114.

[27]      Wu J, Zhang J, Bai Z, Chen S, Cai S. Predictive Factors of Upper Limb MotorRecovery for Stroke Survivors Admitted to a Rehabilitation Program. Eur J PhysRehabil Med, 2020, 56(6): 706-712.

[28]      Feng Y, Zhang J, Zhou Y, Bai Z, Yin Y. Noninvasive BrainStimulation for Patients with a Disorder of Consciousness: A Systematic Reviewand Meta-Analysis. Reviews in the neurosciences, 2020, (0): 000010151520200033.

[29]      BaiZ, Fong KNK, Zhang JJ, Chan J, Ting KH. Immediate and Long-Term Effects ofBci-Based Rehabilitation of the Upper Extremity after Stroke: A SystematicReview and Meta-Analysis. Journal of NeuroEngineering and Rehabilitation, 2020,17(1): 57.

[30]      BaiZ, Fong KNK, Zhang J, Hu Z. Cortical Mapping of Mirror Visual FeedbackTraining for Unilateral Upper Extremity: A Functional near-InfraredSpectroscopy Study. Brain and behavior, 2020, 10(1): e01489.

[31]      BaiZ, Fong KNK. “Remind-to-Move” Treatment Enhanced Activation of the PrimaryMotor Cortex in Patients with Stroke. Brain topography, 2020, 33(2): 275-283.

[32]      Zhang B, Kan L, Dong A, Zhang J, Bai Z, Xie Y, Liu Q, Peng Y. TheEffects of Action Observation Training on Improving Upper Limb Motor Functionsin People with Stroke: A Systematic Review and Meta-Analysis. PloS one, 2019,14(8): e0221166.

[33]      Jin M, Zhang Z, Bai Z, Fong KNK. Timing-Dependent Interaction Effects of Tdcs withMirror Therapy on Upper Extremity Motor Recovery in Patients with ChronicStroke: A Randomized Controlled Pilot Study. Journal of the neurologicalsciences, 2019, 405: 116436.

[34]      BaiZ, Zhang J, Zhang Z, Shu T, Niu W. Comparison between Movement-Based andTask-Based Mirror Therapies on Improving Upper Limb Functions in Patients withStroke: A Pilot Randomized Controlled Trial. Frontiers in Neurology, 2019,10(288).

[35]      BaiZ, Shu T, Niu W. Test-Retest Reliability and Measurement Errors of GripStrength Test in Patients with Traumatic Injuries in the Upper Extremity: ACross-Sectional Study. BMC musculoskeletal disorders, 2019, 20(1): 256.

[36]      BaiZ, Shu T, Hao Y, Niu W. An Alternative Static Progressive Orthosis forForearm Pronation and Supination. Journal of Hand Therapy, 2019, 32(3):403-406.

[37]      BaiZ, Song D, Deng H, Li-Tsang CWP. Predictors for Return to Work afterPhysical Injury in China: A One-Year Review. Work, 2018, 60(2): 319-327.

[38]      BaiZ, Shu T, Lu J, Niu W. Measurement Properties of the Functional RatingIndex: A Systematic Review and Meta-Analysis. Spine, 2018, 43(22): E1340-E1349.


成果介绍

脑卒中

itbs

fnirs实验海报

镜像

tDCS


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