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刘嫦钦,同济大学附属第十人民医院消化内科,医学博士,副主任医师,香港中文大学访问学者,海峡两岸医药卫生交流协会消化病学会炎症性肠病学组委员。
毕业于同济大学医学院,获得同济大学优秀博士学位论文表彰,在国内外发表SCI及核心期刊论文20余篇,多篇SCI为10分以上高分值文章。参与国家自然科学基金青年项目,参与国家自然科学基金面上项目,主持并参与多项市级、院级课题。
临床擅长:炎症性肠病诊疗、生物治疗、疑难肠病诊治、小肠镜、胶囊内镜诊治、胃肠镜下息肉摘除术、早期消化道肿瘤ESD术、超声内镜、消化系统其他疾病等。
(1)局级课题,炎症性肠病专病队列数据库的建立和应用 ,SHDC2024CRI014 ,乌思奴单抗与维得利珠单抗在克罗恩病中的疗效对比研究,15万,在研,主持
(2) 国家自然科学基金委员会, 专项项目, 82341219, 易感基因MFSD12调控肠黏膜免疫细胞-肠道细菌互作参与炎症性肠病发生的机制研究(联合申请A), 2024-01-01 至 2026-12-31, 200万元, 在研, 参与
(3) 国家自然科学基金委员会, 面上项目, 82170536, IPA-AhR通路对炎症性肠病肠黏膜树突状细胞及CD4+T细胞功能调控机制的研究, 2022-01-01 至 2025-12-31, 55万元, 在研, 参与
(1) Changqin Liu; Li-Hua Mo; Bai-Sui Feng; Qiao-Ruo Jin; Yan Li; Jianli Lin; Qing Shu; Zhi Gang Liu; Zhanju Liu; Xiaomin Sun; Ping-Chang Yang ; Twist1 contributes to developing and sustaining corticosteroid resistance in ulcerative colitis, Theranostics, 2021, 11(16): 7797-7812 (期刊论文) ( 本人标注: 共同第一作者 ) ,IF: 12.4
(2) Changqin Liu; Wei Wu; Wenju Chang; Ruijin Wu; Xiaomin Sun; Huili Wu; Zhanju Liu ;miR-31-5p-DMD axis as a novel biomarker for predicting the development and prognosis of sporadic early-onset colorectal cancer, Oncology Letters, 2022, 23(5): 157 (期刊论文) ( 本人标注: 唯一第一作者 ), IF: 2.5
(3) Changqin Liu; Xingzhou Xia; Wei Wu; Ruijin Wu; Maochun Tang; Tengfei Chen; Feng Xu; Yingzi Cong; Xiaorong Xu; Zhanju Liu ; Anti-tumour necrosis factor therapy enhances mucosal
healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn’s disease, Clinical and Experimental Immunology, 2013, 173(1): 102-
111 (期刊论文) ( 本人标注: 共同第一作者 ), IF:3.4
(4) Liesheng Lu; Changqin Liu; Kunpeng Liu; Chenzhang Shi; Zhongchen Liu; Xun Jiang; Feng
Wang ; The causal effects of leisure screen time on irritable bowel syndrome risk from a
Mendelian randomization study, Scientific Reports, 2023, 13(1): 13216 (期刊论文) ( 本人标
注: 共同第一作者 ), IF:3.8
(5) Yulan Ye, Changqin Liu, Ruijin Wu, Dengfeng Kang, Han Gao, Huiying Lv, Zhongsheng Feng, Yanhong Shi, Zhanju Liu, Liang Chen; Circadian clock component PER2 negatively regulates CD4+ T cell IFN-γ, Mucosal Immunology, 2024 Aug 5, Online ahead of print. 共同第一作者 IF:7.9
(6) Changqin Liu, Lijin Feng, Xiaomin Sun; Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma: A Rare Case of Diffuse Ulcers in the Intestine, 2021 Dec;19(12):e121-e122. 共同第一作者 IF: 11.6
(7) Liang Chen, Dengfeng Kang, Leilei Fang, Mingming Sun, Mingsong Li, Guangxi Zhou, Chunjin Xu, Zhi Pang, Yulan Ye, Baisui Feng, Huili Wu, Jian Lin, Baijing Ding, Changqin Liu, Yanhong Shi and Zhanju Liu; Development and validation of a novel therapeutic drug monitoring-based nomogram for prediction of primary endoscopic response to anti-TNF therapy in active Crohn’s disease; Therapeutic Advances in Gastroenterology, 2024 30(17). 共同通讯. IF: 3.9

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