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易婉婉,女,博士,硕士研究生导师,上海市公共卫生优秀青年人才,上海市第十人民医院核医学科副主任医师,长期从事核医学体外诊断工作。主要研究方向为肿瘤微环境中的代谢调控与免疫逃逸机制研究。近年来发表论文十余篇,授权专利6项(其中发明专利3项),主持各级各类课题5项,参与多项国家级重大课题。获上海市科技进步一等奖、江苏医药科技二等奖。
1、上海市卫生健康委员会,上海市公共卫生优秀青年人才项目,GWVI-11.2-YQ51,放射性核素辐射智能监测系统构建及其应用研究,2023-07至2025-06,在研,主持。
2、上海市第十人民医院,研究型医师项目,2023YJXYSB011,内分泌性高血压病因筛查的前瞻性队列研究,2023-07至2025-12,在研,主持。
3、上海市卫生健康委员会,青年项目,20214Y0159, 基于拉曼光谱技术在肝癌肝外转移血清标志物研究, 2022-01至 2024-01, 在研, 主持。
4、 上海市第十人民医院,攀登人才计划, 2021SYPDRC065, 纳米荧光微球法检测穿刺液甲状腺球蛋白临床价值研究, 2021-01至2022-12, 结题, 主持。
5、同济大学,中央高校基本科研业务专项,22120180392,分化型甲状腺癌放射性碘耐受患者尿液中特征性miRNA的研究,2017-07至2018-08,结题,主持。
发表文章
1. Wang Ru,Yu Xiaqing,Cai Haidong,Lu Ganghua, Gao Dingwei,Zhang Mengyu,Chai Li,Yi Wanwan, Lv Zhongwei.Gut microbiota alteration was related to subclinical hypothyroidism and dyslipidemia in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology.2025;39 (5):e70445.doi:10.1096/fj.202402289RR;
2. Mengyu Zhang, Chao Zhang, Haidong Cai,Yuan Xie, Li Chai, Ming Sun, Jin Liu, Jisong Liu, Chong Yi, Hengwei Fan, Wanwan Yi, and Zhongwei Lv. Rapid Determination of Water-Soluble Vitamins in Human Serum by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry. ACS Omega.2025-01-14;10(1):885-891.
3. Liu Xiaoyan, Jiang Wen, Lu Ganghua, Qiao Tingting, Gao dingwei, Zhang Mengyu, Cai Haidong, Chai Li, Yi Wanwan, Lv zhongwei.The Potential Role of Pyrroloquinoline Quinone to Regulate Thyroid Function and Gut Microbiota Composition of Graves' Disease in Mice.Polish Journal of Microbiology.2023;72 (4):443-460.doi:10.33073/pjm-2023-042.
4. Tian Tongguan, Xie Xiao, Yi Wanwan, Zhou Yuefan, Xu Yixin,Wang Zhenxiang, Zhang Junjing, Lin Mingen, Zhang Ruonan, Lv Zhongwei, Li Xinxing, Lv Lei, Xu, Yanping. FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.Cell Rep.2023-11-28;42(11):113362.doi: 10.1016/j.celrep.2023.113362.
5. Tingting Qiao, Dingwei Gao, Gaixia Lu, Wanwan Yi and Zhongwei Lv . Association of gastrointestinal symptoms and skipping breakfast with anxiety and depressive symptoms in quarantined Chinese college students during the Shanghai 2022 lockdown: a cross sectional survey. BMC Psychiatry. 2023-11-28; 23 (1): 889. doi: 10.1186/s12888-023-05317-3. WOS:001109951400003.
6. Tang Jingwen,Yi Wanwan,Yan Jiahao,et al.Highly absorbent bio-sponge based on carboxymethyl chitosan/polyγ-glutamic acid/platelet-rich plasma for hemostasis and wound healing.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023;247:125754.doi:10.1016/j.ijbiomac.2023.125754.
7. Wang Ting,Yi Wanwan,Zhang Yu,et al.Sodium alginate hydrogel containing platelet-rich plasma for wound healing.COLLOIDS AND SURFACES B-BIOINTERFACES.2023;222:113096.doi:10.1016/j.colsurfb.2022.113096.
8. Yi Wanwan, Zhang Mengyu,Yuan XueYu,et al. A model combining testosterone, Androstenedione and free testosterone index improved the diagnostic efficiency of polycystic ovary syndrome. Endocrine Practice.2023;29(8):629-636.doi:10.1016/j.eprac.2023.05.007.
9. Yi Wanwan,Jia Chengyou,Yang Ziyu,et al.Effect of umifenovir (arbidol) versus standard care on clinical outcome in patients with COVID-19: a retrospective cohort study.Therapeutic Advances in Respiratory Disease.2023;17:17534666231183811.doi:10.1177/17534666231183811.
10. Wanwan Yi, Tingting Qiao, Ziyu Yang, Lei Hu, Mingming Sun, Hengwei Fan, Yanping Xu and Zhongwei Lv. The regulation role and diagnostic value of fifibrinogen-like protein 1 revealed by pan-cancer analysis. Materials Today Bio,2022; 12:100470.
11. Wanwan Yi, Xuan Long, Jin Liu, LiShuai Shi, Zichen Chen, Jing Yang, Ziyu Yang, Zhongwei Lv and Hengwei Fan. Risk factors for recurrent positive results of the nucleic acid amplification test for COVID-19 patients: a retrospective study. Human Cell, 2021;34 (6):1744-1754.
12. Ru Wang, Hengwei Fan, Ming Sun, Zhongwei Lv and Wanwan Yi. Roles of BMI1 in the Initiation, Progression,and Treatment of Hepatocellular Carcinoma.Technology in Cancer Research & Treatment, 2022;21:15330338211070689.
13. Wanwan Yi, Jin Liu, Shuping Qu, Hengwei Fan and Zhongwei Lv.An 8 miRNA-Based Risk Score System for Predicting the Prognosis of Patients With Papillary Thyroid Cancer.Technology in Cancer Research & Treatment, 2020;19:1533033820965594.
14. Hengwei Fan, Xiaqing Yu, Xiaohui Fu, Hengmei Zhu, Zhongwei Lv, Wanwan Yi and Qian Zhang.Clinical implications of different specimen types for nucleic acid testing in two cases of COVID-19.Journal of International Medical Research, 2020;48 (8):300060520949067.
15. Shuping Qu, Qiuyuan Shi, Jing Xu, Wanwan Yi and Hengwei Fan.Weighted Gene Coexpression Network Analysis Reveals the Dynamic Transcriptome Regulation and Prognostic Biomarkers of Hepatocellular Carcinoma.Evolutionary Bioinformatics,2020;16:1176934320920562.
16. Lu Hai-Min,Yi Wan-Wan, Ma Yu-Shui,et al.Prognostic implications of decreased microRNA-101-3p expression in patients with non-small cell lung cancer.Oncology Letters, 2018;16 (6):7048-7056.
17. Zhang Chao, Fan Heng-Wei, Yi Wan-Wan and Zhi-Qiang Zheng. Hidden Blood Loss and Its Influential Factors After Laparoscopy-Assisted Gastrectomy for Gastric Cancer. Journal of Laparoendoscopic & Advanced Surgical Techniques, 2018;28 (3):237-241.
获得奖项
2018年荣获先进医务工作者称号
2020年荣获“上海市科技进步一等奖”
2023年荣获“研究型医师”
2023年荣获“江苏医药科技奖二等奖”
授权专利
1、发明专利:加样枪避免倒吸入枪体的装置,2022-07-26,ZL202110689051.X(第1发明人)
2、发明专利:自动去除加样样品中气泡的加样枪,2022-09-16,ZL202110695939.4(第1发明人)
3、实用新型专利:一种可自动更换枪头的加样枪,2021-11-05,ZL202120182705.5(第1发明人)
4、 实用新型专利:一种排枪枪头更换辅助装置,2021-11-05,ZL202120167502.9 (第1发明人)
5、 发明专利:一种检测血液样品中脂溶性维生素的方法,2021-01-15,ZL201910799963.5(第6发明人)
6、实用新型:一种离心管,2021-05-12,ZL202121011367.5 (第6发明人)

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