1. NASP蛋白在调控肿瘤细胞表皮-间质转变中的功能与机制研究，55万，2020.1-2023.12，面上项目，主持

2. 癌组蛋白H3K56M的表观遗传调控机制与靶向干预研究，52万，2023.1-2026.12，面上项目，主持

3. 干细胞衰老的遗传和表观遗传新机制，2022.12-2027.11，科技部重点研发计划，参与

1. NASP蛋白在调控肿瘤细胞表皮-间质转变中的功能与机制研究，55万，2020.1-2023.12，面上项目，主持

2. 癌组蛋白H3K56M的表观遗传调控机制与靶向干预研究，52万，2023.1-2026.12，面上项目，主持

3. 干细胞衰老的遗传和表观遗传新机制，2022.12-2027.11，科技部重点研发计划，参与

·       Yun Feng†, Jin Sun†, Xuan Kang, Yining Wang, Kai Liu, Wenfei Wang, Chen Wan1, Yabin Li,Qian Zhao, Kaile Li, Fang-Lin Sun* and Jianfeng Chang*. NASP implicationin the androgen receptor associated with castration resistance in prostatecancer. Cell Communication and Signaling (2025) 23:331. (*co-corresponding author)

·       Xuan Kang *, Xiaomei Yang, Xiaobo Guo, Yabin Li, Chenxin Yang,Huimin Wei*, and Jianfeng Chang*. Incorporation of a histone mutant withH3K56 site substitution perturbs the replication machinery in mouse embryonicstem cells. Journal of Molecular Cell Biology (2022), 14(3), mjac014. (*co-corresponding author)

·       Yuan-Ya Jing, Feng-Feng Cai, Lei Zhang, JingHan, Lu Yang, Fan Tang, Ya-Bin Li, Jian-Feng Chang, Feng Sun, Xiao-Mei Yang, Fang-LinSun, Su Chen. Epigenetic regulation of the Warburg effect by H2Bmonoubiquitination. Cell Death &Differentiation (2019). 27(5): 1660-1676.

·      Kai-Le Li, Lei Zhang, Xiao-Mei Yang, Qiang Fang, Xue-Fang Yin,Hui-Min Wei, Ting Zhou, Ya-Bin Li, Xue-Lin Chen, Fan Tang, Yong-Hao Li, Jian-Feng Chang*, Wei Li*, Feng Sun*. Histoneacetyltransferase CBP-related H3K23 acetylation contributes to courtshiplearning in Drosophila. BMC DevelopmentalBiology. (2018) 18:20. (*co-correspondingauthor)

·      Xuan Kang, Yun Feng, Zhixue Gan, Shiyang Zeng, Xiaobo Guo,Xirui Chen, Ye Zhang,Chen Wang, Kuinan Liu, Xuelin Chen, Xiaoxue Jianga ShutingSong, Yabin Li, Su Chen,Feng Sun, Zhiyong Mao, Xiaomei Yang, Jianfeng Chang. NASP antagonizechromatin accessibility through maintaining histone H3K9me1 in hepatocellularcarcinoma. BBA - Molecular Basis ofDisease 1864 (2018) 3438–3448. (corresponding author)

·      Ye Zhang*, Jian-Feng Chang*, Jin Sun*, Lu Chen, Xiao-MeiYang, Huan-Yin Tang, Yuan-Ya Jing, Xuan Kang, Zhi-MinHe, Jun-Yu Wu, Hui-Min Wei, Da-Liang Wang,Rong-GangXu, Rui-Bao Zhu, Ying Shen, Shi-Yang Zeng, ChenWang, Kui-Nan Liu,Yong Zhang, Zhi-Yong Mao, Ci-Zhong Jiang and Fang-LinSun. Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin tofacilitate NHEJ and genome stability. J CellSci 2018 131: jcs215525 doi: 10.1242/jcs.215525. (*co-first author)

·      Zekun Liu, Qing-bin Zhang, Chen Bu, Dawei Wang, Kai Yu, ZhixueGan, Jianfeng Chang,  Zhongyi Cheng and Zexian Liu. QuantitativeDynamics of Proteome, Acetylome, and Succinylome during Stem-CellDifferentiation into Hepatocyte-like Cells. J.Proteome Res. 2018, 17, 2491−2498.

·      Su Chen, Yuanya Jing Xuan Kang, Lu Yang, Da-Liang Wang, WeiZhang, Lei Zhang, Ping Chen, Jian-FengChang, Xiao-Mei Yang, Fang-Lin Sun. Histone H2B monoubiquitination is acritical epigenetic switch for the regulation of autophagy. Nucleic acidresearch, (2017) 45 (3),1144-1158.

·      You Wu, Ping Chen, Yu-Long Men, Yuanya Jing, Chen Wang, QiangWang, Zhixue Gan, Jin Huang, Kun Xie, Pei-Chao Chen, Fengfeng Cai, Jian-Feng Chang, Su Chen. Microarrayanalysis reveals the potential biological functions of H2B monoubiquitination. (2015)PLoS ONE 10(7): e0133444.

·      Chen Wang, Jian-FengChang, Da-Liang Wang, Yan Liu, Meng Zhang, Yu-Long Men, Dongdong Lu,Xiao-Mei Yang, Su Chen, Fang-Lin Sun. A Conserved RAD6-MDM2 Ubiquitin LigaseMachinery Targets Histone Chaperone ASF1A in Tumorigenesis. Oncotarget. 2015Oct 6; 6(30): 29599–29613.

·      Jin Sun, Huimin wei, Jiang Xu, Jian-Feng Chang, Zhihao Yang, Xingjie Ren, Wen-Wen Lv, Lu-Ping Liu,Li-Xia Pan, Xia Wang, Huan-Huan Qiao, Bing Zhu, Jun-Yuan Ji, Dong Yan, TingXie, Fang-Lin Sun, and Jian-Quan Ni. Histone H1-Mediated Epigenetic RegulationControls Germline Stem Cell Self-Renewal by Modulating the Acetylation of H4Lysine 16. Nature communications 6, 8856 (2015)

·      Lei Zhao*, Hai-Hui Gu*,Jian-Feng Chang*, Jun-Yu Wu, Da-Liang Wang, Su Chen, Xiao-Mei Yang Bao-HuaQian （2014） MicroRNA-383regulates the apoptosis of tumor cells through targeting Gadd45g. PLoS ONE 9(11): e110472.

·      Fengfeng Cai, Ping Chen, Li Chen, Ewelina Biskup, Yan Liu,Pei-Chao Chen, Jian-Feng Chang, WenjieJiang, Yuanya Jing, Youwei Chen, Hui Jin, Su Chen （2014）Human RAD6 Promotes G1-STransition and Cell Proliferation through Upregulation of Cyclin D1 Expression.PLoS ONE 9(11):e113727

·      Jianfeng Chang, Xuanying Fu, Lizhe An,Jianhui Wang, Shijian Xu, Manxiao Zhang, Huyuan Feng, Tuo Chen. (2006)Properties of cellular ubiquinone and stress-resistance in suspension-culturedcells of Chorispora bungeana during early chilling. Environmental andExperimental Botany 57(1-2), 116-122

·      Xuanying Fu, JianfengChang, Lizhe An, Manxiao Zhang, Shijian Xu, Tuo Chen, Yanhong Liu, Hua Xin,Jianhui Wang. (2006) Association of the cold-hardiness of Chorispora bungeanadistribution and accumulation of calcium in the cells   Environmental and Experimental Botany,55(3), 282-293