团队有7人。

1，ALPPS门静脉结扎侧肝细胞释放外泌体介导线粒体转移 加速残肝再生的机制研究，82570724，国家自然科学基金面上项目，49万，2026.01-2029.12，主持

2，结直肠癌根治标本血外泌体的过氧化氧化还原蛋白1（PRDX1）与术后肝转移发生的前瞻性队列研究，23Y11905400，上海市2023年度“科技创新行动计划”医学创新研究专项项目，2023.12-2026.11，主持

3, IRF-1-Rab27a轴调控的外泌体促进部分肝移植术后肝再生: miR-122/ CXCR4双信号的远程传递，81970565，国家自然科学基金面上项目，55万，2020.01-2023.12，主持

4，上调肿瘤细胞干扰素调节因子1后分泌的外泌体疫苗抗肿瘤机制研究及疫苗开发，18JC1414000，上海市科技创新计划基础研究项目，20万，2018.06-2021.05，主持，已结题

1，ALPPS门静脉结扎侧肝细胞释放外泌体介导线粒体转移加速残肝再生的机制研究，82570724，国家自然科学基金面上项目，49万，2026.01-2029.12，主持

2，结直肠癌根治标本血外泌体的过氧化氧化还原蛋白1（PRDX1）与术后肝转移发生的前瞻性队列研究，23Y11905400，上海市2023年度“科技创新行动计划”医学创新研究专项项目，2023.12-2026.11，主持

3, IRF-1-Rab27a轴调控的外泌体促进部分肝移植术后肝再生: miR-122/ CXCR4双信号的远程传递，81970565，国家自然科学基金面上项目，55万，2020.01-2023.12，主持

4，上调肿瘤细胞干扰素调节因子1后分泌的外泌体疫苗抗肿瘤机制研究及疫苗开发，18JC1414000，上海市科技创新计划基础研究项目，20万，2018.06-2021.05，主持，已结题

1，Shengming Wu, Chenlong He, Huawei Liu, Han Zhou, Jingwen Qin, Ming Yin, Muqing Yang (共同通讯), Wenjie Tang, Yilong Wang. Upconersion Nanoparticle@TiO2-Nitrate System to Generate Nitrate Radicals for Deep Tissue Penetration in Tumor Catalytic Therapy. Acta Biomaterialia 2025. Accepted.

2，Wen-ya Li, Mu-qing Yang (共同第一作者), et al. Three-dimensional technology in biliary tract reconstruction for cholangiocarcinoma after hepatectomy.  HBPI 2025. accepted.

3，Zhu Y, Gu J, Lu Y, Tao Q,Cao X, Zhu Y, YangMQ (共同通讯), Liang X. IL-6 Released from HepaticStellate Cells Promotes Glycolysis and Migration of HCC Through theJAK1/vWF/TGFB1 Axis. J Hepatocell Carcinoma.2024;11:1295-1310 (IF=4.2，JCR Q2)

4，Zhu Y, Lu Y, Zhu Y, RenX, Deng Q,Yang MQ (共同通讯), Liang X. ST2L promotesVEGFA-mediated angiogenesis in gastric cancer by activatingTRAF6/PI3K/Akt/NF-κB pathway via IL-33. Sci Rep. 2024;14(1):26393

5, Liu B, Yang MQ (共同第一作者), Yu TY, et al. Mast Cell Tryptase Promotes Inflammatory Bowel Disease–Induced Intestinal Fibrosis. Inflammatory Bowel Disease 2021 Jan 19;27(2):242-255(IF:4.2)

6, Yang MQ, Du Q, Goswami J, et al. IRF-1-Rab27a regulated extracellular vesicles promote liver ischemia/reperfusion injury. Hepatology 2018 Mar;67(3):1056-1070 (IF:14.0)

7, Yang MQ, Du Q, Varley PR, et al. Interferon regulatory factor 1 (IRF-1) priming tumor derived exosomes enhances antitumor immune response. British J of Cancer. 2018 Jan;118(1):62-71 （5.6）

8, Ma YY, Yang MQ (共同第一作者), He ZG, et al. Upregulation of heme oxygenase-1 in Kupffer cells blocks mast cell degranulation and inhibits dendritic cell migration in vitro. Mol Med Rep. 2017 Jun;15(6)3796-3802

9, Wen X, Yang MQ (共同第一作者), Gao Ming, et al. MiR-21-3p and miR-21-5p in tumor tissue as diagnostic biomarkers for gastric cancer. Int J ClinExpPathol 2016; 9(7):7195-7201

10, Yang MQ, Ma YY, Tao SF, et al. Mast cell degranulation plays a role in ischemia and reperfusion injury. J Surg Res. 2014 Jan; 186(1): 170-8

11, Yang MQ, Ma YY, Ding J, et al. Preconditioning donor livers with cromolyn or compound 48/80 prolongs recipient’s survival in a rat orthotopic liver transplantation model. Transplant Proc. 2014 Jun; 46(5): 1554-9

12, Yang MQ, Ma YY, Ding J, et al. The effects of mast cell in ischemia and reperfusion injury. Inflamm Res. 2014 Nov; 63(11): 899-905

13, Ma YY, Yang MQ (共同第一作者), Wamg CF, et al. Inhibiting mast cells degranulation by HO-1 affects dendritic cells maturation in vitro. Inflamm Res. 2014 Jul; 63(7): 527-37

其他文章：

1，Pan Y，Tan WF, Yang MQ, Li JY, David AG. The therapeutic potential of exosomes derived from different cell sources in liver diseases. Am J PhysiolGastrointest Liver Physiol. 2022 Feb 2. (online ahead of print)

2，Zhang Y, Xie R, Zhang H, Zheng Y, Lin C, Yang L, Huang M, Song F, Lu L, Yang M, et al. Integrin β7 inhibits colorectal cancer pathogenesis via maintaining antitumor immunity. Cancer Immunol Res.2021 Aug;9(8):967-980

3，Wan J, Zhang ZC, Yang MQ, et al. Minimally invasive surgery for glycogen storage disease combined with inflammatory bowel disease: A case report. Word J Clin Cases. 2021 Jun 16;9(17)4342-4347

4，Deng X, Pan Y, Yang M, et al. PLOD3 is associated with immune cell infiltration and genomic instability in colon adenocarcinoma. Biomed Res Int. 2021 Jun 18;2021:4714526

5，Feng J, Wei Q, Yang M, et al. Development and validation of a novel miRNA classifier as a prognostic signature for stage II/III colorectal cancer. Ann Transl Med. 2021 May;9(9):747

6，Zeng F, Chen Z, Chen R, Shufesky WJ, Bandyopadhyay M, Camirand G, Oberbarnscheidt MH, Sullivan MLG, Baty CJ, Yang MQ, et al. Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation. SciTransl Med.2021 Mar 17;13(585):eabb0122

7，Yuan X, Chen H, Chen C, Yang M, et al. Minimally invasive treatment of mid-low rectovaginal fistula: a transanal endoscopic surgery study. SurgEndosc. 2020 Sep;34(9):3971-3977

8，Feng J, Yang M, Wei Q, et al. Novel evidence for oncogenic piRNA-823 as a promising prognostic biomarker and a potential therapeutic target in colorectal cancer. J Cell Mol Med. 2020 Aug;24(16):9028-9040

9，Du Q, Luo J, Yang MQ, et al. iNOS/NO is required for IRF1 activation in response to liver ischemia-reperfusion in mice. Mol Med. 2020 Jun 9;26(1):56

10，Chen H, Chen C, Yuan X, Xu W, Yang MQ, et al. Identification of immune cell landscape and construction of a novel diagnostic nomogram for Crohn’s disease. Front Genet. 2020 Apr 29;11:423

11，Li W, Deng M, Loughran PA, Yang M, et al. LPS induces active HMGB1 release from hepatocytes into exosomes through the coordinated activities of TLR4 and Caspase-11/GSDMD signaling. Front Immunol. 2020 Apr 3;11;229

12，Wu X, Chen C, Yang M, et al. Squamous cell carcinoma malignantly transformed from frequent recurrence of a presacral epidermoid cyst: report of a case. Front Oncol. 2020 Apr 3;10:458

13，Chen C, Chen H, Yang M, et al. Laparoscopy-Assisted natural orifice specimen extraction to treat tumors of the sigmoid colon and rectum: the short- and long-term outcomes of a retrospective study. J LaparoendoscAdvSurg Tech A. 2019 Jun;19(6):801-808

14，He Z, Song J, Hua J, Yang M, et al. Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colos. Cell Death Dis. 2018 Dec 5;9(12):1173

15，Yu T, Liu B, He Z, Yang M, et al. Short-term in vitro culture of purity and highly functional rat bone marrow-derived mast cells. In Vitro Cell Dev Biol Anim. 2018 Dec;54(10):705-714

16，He Z, Ma S, Yang M, et al. Degranulation of gastrointestinal mast cells contributes to hepatic ischemia-reperfusion injury in mice. ClinSci (Lond). 2018 Oct 29;132(20):2241-2259

17，Wang R, Li Y, Tsung A, Huang H, Du Q, Yang M, et al. iNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway. PNAS. 2018 Oct 23;115(43):E10127-E10136

18，Yu T, He Z, Yang M, et al. The development of methods for primary mast cells in vitro and ex vivo: an historical review. Exp Cell Res. 2018 Aug 15;369(2):179-186