主持科研项目：

1. 国家自然科学基金面上项目，8227020693，细胞基质蛋白CCN5介导促血管生成素信号通路调控内皮细胞血管新生作用和机制研究。

2. 国家自然科学基金青年项目，8190112030，缺氧状态Foxp1通过Hif1α-Hk2通路抑制血管新生阻止肿瘤生长的机制研究。

3. 上海市卫健委优秀青年医学人才培养计划，2022YQ035，CCN5抑制血管新生机制研究。

4. 浦东新区卫生系统优秀青年医学人才培养计划，PWRq2021-04，血管新生机制研究。

5. 上海市东方医院院内青年人才项目。

主要参与科研项目：

1. 国家自然科学基金重点（宏观领域）项目，82130016，Foxp1在动脉粥样硬化病程中调控巨噬细胞异质性的分子机制研究，在研。

2. 国家自然科学基金重大研究计划培育项目，91639112，Foxp1介导IL-b/Lox-1调节内皮细胞/单核巨噬细胞交互作用 在动脉粥样硬化发生发展中作用2017/01-2019/12，已结题。

3. 国家重点基础研究计划-973项目，2014CB965100，人胚胎干细胞衍生细胞治疗心肌梗死后心力衰竭的关键科学问题研究(多模态评估临床前hESCs衍生细胞移植安全性、有效性和功能整合，2014/01-2018/08，已结题。

2022

1. Chen, Xiaoli; Xu,Jianfei; Bao, Wenzhen; Li, Hongda; Wu, Wenrun; Liu, Jiwen; Pi, Jingjiang;Tomlinson, Brian; Chan, Paul; Ruan, Chengchao; Zhang, Qi; Zhang, Lin; Fan,Huimin; Morrisey, Edward; Liu, Zhongmin; Zhang, Yuzhen; Lin, Li; Liu, Jie; Zhuang,Tao, Endothelial Foxp1 Regulates Neointimal Hyperplasia Via MatrixMetalloproteinase-9/Cyclin Dependent Kinase Inhibitor 1B Signal Pathway, Journalof the American Heart Association, 2022, 11(15): e026378.

2. Lu, Qizheng; Liu,Haibo; Zheng, Hao; Zhang, Youming; Ou, Jinbo; You, Jieyun; Zhang, Qi; Pi,Jingjiang; Yao, Xiaobo; Xu, Jing; Wang, Xingxu; Wang, Yunkai; Pei, Ning; Shen,Yunli, SS-31 Modification Inhibits the Proinflammatory Effect on MacrophagesInduced by Superparamagnetic Iron Oxide Nanoparticles, Journal of BiomedicalNanotechnology, 2022, 18(5): 1413-1422.

3. Liu, Chang; Liu,Liping; Wang, Yinglu; Chen, Xiaoli; Liu, Jie; Peng, Sheng; Pi, Jingjiang;Zhang, Qi; Tomlinson, Brain; Chan, Paul; Zhang, Lin; Fan, Huimin; Zheng, Liang;Liu, Zhongmin; Zhang, Yuzhen, Hyperhomocysteinemia Increases Risk of MetabolicSyndrome and Cardiovascular Death in an Elderly Chinese Community Population ofa 7-Year Follow-Up Study, Frontiers in Cardiovascular Medicine, 2022, 8:811670.

4. Wang, YingLu; Liu,Chang; Liu, Liping; Chen, Xiaoli; Wei, Lu; Liu, Jie; Peng, Sheng; Pi,Jingjiang; Zhang, Qi; Tomlinson, Brian; Chan, Paul; Zhang, Lin; Fan, Huimin;Zheng, Liang; Liu, Zhongmin; Zhang, Yuzhen, Association of Elevated ThyroidStimulating Hormone with Atherosclerotic Cardiovascular Disease and ItsMortality in Elderly Community-Dwelling Chinese, Clinical Interventions inAging, 2022, 17: 1139-1150.

2021

1. Kuang, Yashu; Li,Xiaolin; Liu, Xiuxiang; Wei, Lu; Chen, Xiaoli; Liu, Jie; Zhuang, Tao; Pi,Jingjiang; Wang, Yanfang; Zhu, Chenying; Gong, Xin; Hu, Hao; Yu, Zuoren; Li,Jiming; Yu, Ping; Fan, Huimin; Zhang, Yuzhen; Liu, Zhongmin; Zhang, Lin,Vascular endothelial S1pr1 ameliorates adverse cardiac remodelling viastimulating reparative macrophage proliferation after myocardial infarction, CardiovascularResearch, 2021, 117(2): 585-599.

2. Zhu, Jingqi; Yang,Zhangwei; Li, Xiaolin; Chen, Xiaoli; Pi, Jingjiang; Zhuang, Tao; Liu, Jie; Li,Gang; Peng, Sheng; Zhang, Lin; Zhang, Qi; Chan, Paul; Tomlinson, Brian; Fan,Huimin; Zheng, Liang; Liu, Zhongmin; Zhang, Yuzhen, Association of PeriaorticFat and Abdominal Visceral Fat with Coronary Artery Atherosclerosis in ChineseMiddle Aged and Elderly Patients Undergoing Computed Tomography CoronaryAngiography, Global Heart, 2021, 16(1): 74.

2019

1.ZhuangT, Liu J, Chen X, Zhang L, Pi J, Sun H, Li L, Bauer RC, Wang H, Yu Z, Zhang Q,Tomlinson B, Chan P, Zheng X, Morrisey E, Liu Z, Reilly M, Zhang Y. EndothelialFoxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 InflammasomeActivation. Circ Res. 2019 Jul 18. doi: 10.1161/CIRCRESAHA.118.314402.

2.LiuJ, Zhuang T, Pi J, Chen X, Zhang Q, Li Y, Wang H, Shen Y, Tomlinson B, Chan P,Yu Z, Cheng Y, Zheng X, Reilly M, Morrisey E, Zhang L, Liu Z, Zhang Y.Endothelial Foxp1 Regulates Pathological Cardiac Remodeling ThroughTGF-β1-Endothelin-1 Signal Pathway. Circulation. 2019 Jun 10. doi:10.1161/CIRCULATIONAHA.119.039767.

3.ZhuangT, Liu J, Chen X, Pi J, Kuang Y, Wang Y, Tomlinson B, Chan P, Zhang Q, Li Y, YuZ, Zheng X, Reilly M, Morrisey E, Zhang L, Liu Z, Zhang Y. Cell-SpecificEffects of GATA (GATA Zinc Finger Transcription Factor Family)-6 in VascularSmooth Muscle and Endothelial Cells on Vascular Injury Neointimal Formation.Arterioscler Thromb Vasc Biol. 2019 May;39(5):888-901. doi:10.1161/ATVBAHA.118.312263

4.WangY, Liu J, Chen X, Sun H, Peng S, Kuang Y, Pi J, Zhuang T, Zhang L, Yu Z,Tomlinson B, Chan P, Chen Y, Zhang Y, Li Y. Dysfunctional endothelial-derivedmicroparticles promote inflammatory macrophage formation via NF-кB and IL-1βsignal pathways. J Cell Mol Med. 2019 Jan;23(1):476-486. doi:10.1111/jcmm.13950. Epub 2018 Oct 18.

2018

1.PiJ, Liu J, Zhuang T, Zhang L, Sun H, Chen X, Zhao Q, Kuang Y, Peng S, Zhou X, YuZ, Tao T, Tomlinson B, Chan P, Tian Y, Fan H, Liu Z1, Zheng X, Morrisey E,Zhang Y. Elevated Expression of miR302-367 in Endothelial Cells InhibitsDevelopmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways.Theranostics 2018; 8(6): 1511-1526.

2.YuanJ, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J,Li C, Zhong X, Montone KT, Guan G, Tanyi JL, Fan Y, Xu X, Morgan MA, Long M,Zhang Y, Zhang R, Sood AK, Rebbeck TR, Dang CV, Zhang L. Integrated Analysis ofGenetic Ancestry and Genomic Alterations across Cancers. Cancer Cell. 2018 Oct8;34(4):549-560.e9.

2017

1.Pi J, Tao T, Zhuang T, Sun H, Chen X, Liu J, Cheng Y, Yu Z, Zhu HH, Gao WQ, SuoY, Wei X, Chan P, Zheng X,Tian Y, Morrisey E, Zhang L, Zhang Y. A MicroRNA-302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via RestrictingAngiogenesis and Improving Vascular Stability. Circulation Research. 2017 Jan6; 120(1):85-98. 2017

2.Pi J, Cheng Y, Sun H, Chen X, Zhuang T, Liu J, Li Y, Chang H, Zhang L, Zhang Yet al: Apln-CreERT:mT/mG reporter mice as a tool for sprouting angiogenesisstudy. BMC ophthalmology 2017, 17(1):163.

3.Yang L, Zhang Y, Shan W, Hu Z, Yuan J, Pi J, Wang Y, Fan L, Tang Z, Li C et al:Repression of BET activity sensitizes homologous recombination-proficientcancers to PARP inhibition. Science translational medicine 2017, 9(400).

2016

1.KuangY, Li X, Chen X, Sun H, Tomlinson B, Chan P, Zheng L, Pi J, Peng S, Wu H, DingX, Qian D, Shen Y, Yu Z, Fan L,Chen M, Fan H, Liu Z, Zhang Y. Higher prevalenceof elevated LDL-C than non-HDL-C and low statin treatment rate in elderlycommunity-dwelling Chinese with high cardiovascular risk. Sci Rep. 2016 Sep30;6:34268. doi: 10.1038/srep34268.