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严沁，男，医学博士，主任医师，美国威斯康星大学麦迪逊分校访问学者，中华医学会妇科肿瘤学会委员，上海市医学会妇科肿瘤学分会副主任委员，上海市医师协会妇科肿瘤学医师分会委员。从事妇产科临床、教学、科研工作24年，熟练掌握妇科常见病、多发病及疑难病的诊治。尤其擅长妇科良性肿瘤，包括子宫肌瘤、子宫内膜异位症，卵巢肿瘤，子宫脱垂，不孕症等腹腔镜微创手术治疗。擅长子宫颈癌、子宫内膜癌、卵巢癌的综合诊治。发表各类文章60余篇，参编书籍2本。参加课题获上海市科技进步一等奖。
上海市科学与技术委员会, 新兴前沿课题, 20Z11900701, 基于分子分型的子宫内膜癌前哨淋巴结评估新模式及临床应用研究, 2020-12 至 2024-12, 100万元, 在研, 主持
组蛋白甲基转移酶DOT1L增强PD-L1转录促进子宫内膜癌免疫逃逸的分子机制及靶向治疗策略研究. 上海市科委. 03/2023-03/2026，100万元, 在研, 主持
(1) Mengfei Wang; Qin Yan; Yunfeng Song; Zhenbo Zhang; Xiaojun Chen; Kun Gao; Xiaoping Wan ;Loss-of-function mutations of SOX17 lead to YAP/TEAD activation-dependent malignant transformation in endometrial cancer, Oncogene, 2023, 42(4): 322-334
(2) Guo, Yu-E; Li, Yiran; Cai, Bailian; He, Qizhi; Chen, Guofang; Wang, Mengfei; Wang, Kai; Wan, Xiaoping; Yan, Qin Y ; Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing., Aging (Albany NY), 2021, 13(5): 6565-6591
(3) Liu, Binya; Chen, Guofang; He, Qizhi; Liu, Minhao; Gao, Kun; Cai, Bailian; Qu, Junjie; Lin, Shaojian; Geng, Anke; Li, Shuangdi; Wang, Kai; Mao, Zhiyong; Wan, Xiaoping; Yan, Qin Y ; An HMGA2-p62-ERα axis regulates uterine leiomyomas proliferation., The FASEB Journal, 2020, 34(8):10966-10983
(4) Ye, Lei; Li, ShuangDi; Lu, Wen; He, QiZhi; Li, YiRan; Li, BiLan; Wang, XiaoJun; Yan, Qin Y ;Wan, XiaoPing ; A Prospective Study of Sentinel Lymph Node Mapping for Endometrial Cancer: Is It Effective in High-Risk Subtypes?, Oncologist, 2019, 24(12): e1381-e1387
(5) Jing Zhang; Lei Liu; Yunyan Sun; Jiandong Xiang; Dongmei Zhou; Wang Li; Huali Xu; Xiaoming Yang; Na Du; Meng Zhang; Qin Yan Q ; Xiaowei Xi ; MicroRNA-520g promotes epithelial ovarian cancer progression and chemoresistance via DAPK2 repression, Oncotarget, 2016, 7(18): 26516-26534
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