真菌病科成立于2011年，是上海市皮肤病医院优势特色学科和重点培育学科之一，由甲病诊疗中心、医学真菌实验室和真菌感染病房组成。学科针对浅部真菌病、甲真菌病、皮肤癣菌病、趾甲嵌甲、甲沟炎形成门诊治疗轻中度，病房治疗中重度的一体化、特色化专病诊疗模式。针对疑难、罕见的深部皮肤感染，形成真菌病科、检验科、超声科、影像科、中医科、外科等多学科综合诊治模式。始终强调门诊诊疗的规范化、疾病诊断的精准化，探索真菌病、甲病治疗的多元化和个体化。门诊开设有皮肤真菌和甲病（甲癣甲沟炎）、疑难真菌病专病门诊、专家门诊、特需门诊。

甲病诊疗中心致力于甲病的综合诊疗和精准诊断，发展甲真菌病、嵌甲、甲沟炎的非药物治疗方法，为患者提供规范的个体化、精准化诊疗，设有甲癣甲沟炎专病门诊，每年诊治1万余人。针对甲真菌病，在上海市率先开展药物溶甲术、病甲磨削术、脉冲激光治疗甲真菌病的新技术，开创了药物溶甲联合脉冲激光续贯治疗甲真菌病的治疗模式，针对不同患者制定个性化治疗方案；针对嵌甲、甲沟炎，率先开展了无创或微创的非手术矫正技术，获得众多患者好评。

目前学科有临床医师13人，医技人员4人，治疗护士2人，专职科研人员1人。其中高级职称5人，博士4人。学科专注于皮肤真菌病及甲病的临床诊疗和基础科研，先后获上海市皮肤病医院青年人才培养项目5项、公派出国人才项目2项，承担国家自然科学基金5项、上海市科委课题3项、申康中心专项项目2项、上海市卫健委课题7项和同济大学培育项目1项，发表50篇国内外学术论文。科室为同济大学、上海中医药大学硕士研究生培养点、上海市住院医师规范化培训基地和皮肤科专科医师培训基地。

1.  国家自然科学基金委员会，面上项目，8217121063，乙醇脱氢酶ADH2通过药物转运蛋白Cdr1逆转白念珠菌氟康唑耐药的机制，2022-01至2025-12，55万元，在研，主持

1.  国家自然科学基金委员会，面上项目，8217121063，乙醇脱氢酶ADH2通过药物转运蛋白Cdr1逆转白念珠菌氟康唑耐药的机制，2022-01至2025-12，55万元，在研，主持

1.       Qian Yu†, Lulu Li†, Yuanyuan Wang†, Zhiqin Gao, Siyu Liu,Jingwen Tan, Xiaoping Liu, Wei Li* and LianjuanYang*.Clinical experience of primary subcutaneous mycoses in Shanghai: a retrospectiveanalysis. Front. Cell. Infect. Microbiol. 2025，15:1520608.

2.       Chunjiao Zheng1, Wei Li†, Zhiqin Gao, Qian Yu* and Lianjuan Yang*. Deep cutaneousfungal infection in an immunocompetent individual caused by a biologicalpesticide: a rare case report. BMC Infectious Diseases, (2025) 25:341.

3.       Yuanyuan Wang,*, Huan Xue,*,Hejun Dai, Lianjuan Yang*.Cross-Reactivity: a Case ofParacetamol-Induced Generalized Bullous Fixed Drug Eruption Followed byDipyrone-Induced Fixed Drug Eruption. Clinical, Cosmetic and InvestigationalDermatology. 2025:18 785–789.

4.       Qing Cai1,Li Meng,Xiaoping Liu,ZhiqinGao,Hongjin Ren,Jingwen Tan, Lianjuan Yang*.A randomised comparativestudy of 1064 nm Nd:YAG laser and Urea occlusion therapy with topicalmiconazole for the treatment of onychomycosis. Lasers in Medical Science (2025)40:213.

5.       Hao Cui, Dandan Yang, ShengweiGong, Yaling Zhang, Bin Dong, Chang Su, Lianjuan Yang*, Yang Lu*. Thetranscription factor Ofi1 is critical for white-opaque switching in naturalMTLa/α isolates of Candida albicans. Mol Microbiol,2024Jan 3.

6.       Li Meng, Qing Cai, HuaijianZhang, Zhiqin Gao, Lianjuan Yang*.hsa‑miR‑1‑3p and hsa‑miR‑361‑3p as potentialbiomarkers for onychomycosis: A pilot study. Biomed Rep. 2024 Nov 28;22(2):20.

7.       Qian Yu, Yuanyuan Wang, ZhiqinGao, Hong Yang, Siyu Liu, Jingwen Tan, Lianjuan Yang*.DNA microarraychip assay in new use: early diagnostic value in cutaneous mycobacterialinfection. Front CellInfect Microbiol. 2023 Jul 1:13:1183078.

8.       Siyue Kan,Jingwen Tan, Qing Cai,Lulu AnZhiqin Gao, Hong Yang,Siyu Liu, Risong Na,Lianjuan Yang*.Synergisticactivity of the combination of falcarindiol and itraconazole invitro against dermatophytes. Front. Cell. Infect. Microbiol., 03 May 2023.

9.       Lulu An, Jingwen Tan, YuanyuanWang, Siyu Liu, Yongyong Li, Lianjuan Yang*. Synergistic Effect ofthe Combination of Deferoxamine and Fluconazole In Vitro and In Vivo againstFluconazole-Resistant Candida Spp. Antimicrob Agents Chemother. 2022 Nov15;66(11):e0072522.

10.    Tan J, Yu Q, Gao Z, Yang H,Chen Q, Yang L*.Case report: Severe deep ulcer on the left abdomenmimicking mycosis fungoides caused by Trichophyton tonsurans in apatient with novel CARD9 mutation. Front Immunol, 2022, Sep 28:13:1015000.