国家自然科学基金面上项目（2024.01-2027.12），MuERV-L临接的lncRNA在小鼠合子基因组激活中的功能和作用机制。

科技部重点研发项目子课题（2022.12-2027.11），胚层类器官模型标准化制备与药物筛选。

国家自然科学基金面上项目（2022.01-2025.12），重复序列RNA在多能性细胞命运决定中的功能和作用机制。

科技部重点研发项目子课题（2019.07-2024.06），心脏前体细胞的精确定位及表观遗传分析。

科技部重点研发项目子课题（2018.12-2021.12），早期胚胎去分化和全能性维持的分子调控机制。

国家自然科学基金面上项目（2019.01-2022.12），NEDD8激活酶UBA3在干细胞多能性获得与维持中的作用机制。

1. Zhang D^*, Tang Y^*, Ye W^*, Yang D, Qin S, Liu J, Su N, Huang R, Shi G, Xu D, Kou X, Zhao Y, Wang H, Gao S^#, Wei K^#, Kang L^# (2025)

PKM1is required for embryonic cardiomyocyte proliferation through energetic regulation of NFYa stability.

National Science Review 2025 Sep 25;13(1):nwaf408.

2. WuL^*, Shen J, Hou Z, Zhang Y, Bi Y, Zhang R, Bai H, Ye W, Chen K, ZhuJ, Xi C, Xu Y, Kou X, Zhao Y, Li C, Fan H, Le R, Wang Y, Xu X, Xu S, Wang H,Gao S^#, Kang L^#(2025)

Obox1 deficiency impairs fertility in female mice.

Fundamental Research 2025Apr 19;5(4):1570-1580.

3. ZhangJ^*, Xiang S^*, Liu D^*, Pei X^*, ChenM, Zhao Y, Wang Y, Wang Q, Kang L^#, Yu Z^#,Mi J^#, Xiong W^# (2025)

KDM6A down regulation promotes tumor-prone cytokines expression in cancer-associated fibroblasts by activating enhancers.

Cell Death and Disease 2025 Jul 14;16(1):523.

4. Chen K*, Liu W*, Zhu J*, Kou X, Zhao Y, Wang H,Jiang C#, Gao S#, Kang L# (2024)

Pivotal role for long noncoding RNAs in zygotic genome activation in mice.

Science China Life Sciences2024 May;67(5):958-969.

5. Zhu J*, Chen K*, Sun Y*, Ye W, Liu J, Zhang D, SuN, Kou X, Zhao Y, Wang H, Gao S#, Kang L#(2023)

LSM1-mediated Major Satellite RNA decay is required for non-equilibrium histone H3.3 incorporation into parental pronuclei.

Nature Communications 2023 Feb 21;14(1):957. 

6. Wu L*, He S*, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J,Cao S, Chen K, Le R, Xi C, Kou X, Zhao Y, Wang H, Kang L#, Gao S# (2021)

Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress. 

Cell Proliferation 2021 Nov;54(11):e13133. 

7. He J*, Ye W*, Kou N*, Chen K, Cui B, Zhang X, HuS, Liu T#,Kang L#, Li X#(2020)

MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion viaIL32/AKT signalling pathway. 

Journal of Cellular and Molecular Medicine 2020 Jan;24(1):841-849. 

8. Kang L*, Chen JY*, Gao SR# (2018)

Historical review of reprogramming and pluripotent stem cell research in China. 

Yi Chuan 2018 Oct 20;40(10):825-840.

9. Wu L*, Wu Y, Peng B, Hou Z, Dong Y, Chen K, Guo M, Li H, Chen X, Kou X, Zhao Y, BiY, Wang Y, Wang H, Le R#, Kang L#, Gao S#(2017)

Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation. 

Stem Cell Reports 9(5):1692-1705.

10. Li X*, Ma C*, Zhang L*, Li N, Zhang X, He J, HeR, Shao M, Wang J, Kang L#, Han C# (2017)

LncRNA AC132217.4,a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression.

Cancer Letters 407:45-56.

11. Qin S, Yang D, Chen K, Li H, Zhang L, Li Y, Le R, Li X^#, Gao S^# and Kang L^# (2017)

Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs.

Oncotarget 8:84276-84284.

12. Feng X*, Xu X*, Xiao X*, Zou K*, Yu W, Wu J, Tang R, Gao Y, Hao J,Zhao X, Liao Y, Chen Y, Huang W, Guo W#, Kang L#, Deng W#(2017)

NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer.

Cell Death & Disease 8(5):e2783. 

13. Wang M*, Zhang Y*, Wang T*, Zhang J*, Zhou Z, Sun Y, Wang S, Shi Y, Luan X, Zhang Y, Wang Y, Wang Y, Zou Z#, Kang L#, Liu H# (2017)

The USP7 Inhibitor P5091 Induces Cell Death in Ovarian Cancers with Different P53 Status.

Cellular Physiology and Biochemistry 43(5):1755-1766.

14. Hao J*, Xu H*, Luo M*, Yu W*, Chen M, Liao Y, Zhang C, Zhao X, Jiang W, Hou S, Feng X, Zou K, Chen Y, Huang W, Guo W#, Kang L#, Deng W#(2017)

The tumor-promoting role of TRIP4 in melanoma progression and its involvement in responseto BRAF-targeted therapy.

Journal of Investigative Dermatology 138(1):159-170.

15. Kang L*, Gao S#.(2015)

Generation of Viable Mice from Induced Pluripotent Stem Cells (iPSCs) Through Tetraploid Complementation.

Methods in Molecular Biology. 2015;1330:125-32.

16. Kang L#*, Wu J*, Tao Y*, Li H, Liu X, Gao S#, Wang Q#(2015)

Cell Type-Specific Expression Profile and Signaling Requirements in Early Hematopoietic Reprogramming.

Stem Cells and Development 24(12):1483-92. 

17. Kang L*,Gao S# (2012)

Pluripotency of induced pluripotent stem cells.

Journal of Animal Science andBiotechnology 2012 Feb 28;3(1):5. 

18. Kang L*, Wu T, Tao Y, Yuan Y, He J, Zhang Y, Luo T, Kou Z, Gao S# (2011)

Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation.

Cell Research 21(3):546-9. 

19. Kang L*, Kou Z*, Zhang Y, Gao S# (2010)

Induced pluripotent stem cells (iPSCs)--a new era of reprogramming.

Journal of Genetics and Genomics 7(7):415-21. 

20. Kou Z*, Kang L*, Yuan Y, Tao Y, Zhang Y, Wu T, HeJ, Wang J, Liu Z, Gao S# (2010)

Mice cloned from induced pluripotent stem cells(iPSCs).

Biology of Reproduction 83(2):238-43. 

21. Kang L*, Wang J, Zhang Y, Kou Z, Gao S# (2009)

iPS cells can support full term development of tetraploid blastocyst-complemented embryos.

Cell Stem Cell 5(2):135-138.