本团队现有在读博士生7名，硕士生两名。

入选国家自然科学基金委优秀青年科学基金获得者（2021）、上海市科委青年科技启明星（A类）获得者（2021），上海市晨光计划获得者（2015年），主持国家自然科学基金青年项目（结题）和面上项目（在研）各一项，作为骨干参与国家重点研发计划两项。

主持项目和人才计划

1. 国自然优秀青年科学基金项目，32122030，2022/01-2024/12， 在研

2. 上海市科委青年科技启明星计划，21QA1409500，2021/07-2024/06，在研

3. 国家自然科学基金面上项目, 31970758,  2020/01-2023/12,  在研

4. 国家自然科学基金青年项目,  31501183,  2016/01-2018/12,  结题

5. 上海市教委晨光计划项目, 15CG19, 2016/01-2018/12, 结题

发表论文：

1.      Le, R.R.#*;Huang, YY.X.#, Zhang, Y.P.#, Wang, H.#, Lin, J.M.#, Dong, Y., Li, Z.Y., Guo, M.Y.,Li, Z.Y., Guo, M.Y., Kou, X.C., Zhao, Y.H., Chen, M., Zhu, Q.S., Zhao, A.Q.,Yin, J.Q., Sung, J.T., Su, Z.Q., Shi, K.R., Gao, Y.W., Chen, J.Y., Liu, W.Q., Kang,L., Wang, Y.X., Li, C., Liu, X.Y., Gao, R., Wang, H., Ju, Z.Y.*; Gao,S.R.*(2021). Dcaf11 activates Zscan4-mediated alternative telomere lengthening inearly embryos and embryonic stem cells. Cell Stem Cell, 2020, 28: 1-16. IF: 25.

2.      Le, R.R.#,Kou, Z.H., Jiang, Y.H., Li, M., Huang, B., Liu, W.Q., Li, H., Kou, X.C., He, W.Z.,Rudolph, K.L., Ju, Z.Y.*, Gao, S.R.*(2014). Enhanced telomere rejuvenation inpluripotent cells reprogrammed via nuclear transfer relative to inducedpluripotent stem cells. Cell Stem Cell, 2014, 14(1): 27-39. IF: 25.

3.      Zhang,Y.P.#, Huang, Y.X.#, Dong, Y., Liu, X.Y., Kou, X.C., Zhao, Y.H., Zhao, A.Q.,Sun, J.T., Su, Z.Q., Li, Z.Y., Zhang, H., Li, Y.W., Cao, S.Y., Wei, J.H., Yin,J.Q., Kang, L., Gao, Y.W., Chen, J.Y., Wang, Y.X., Li, C., Gao, R., Wang, H.,Gao, S.R.*, Le, R.R.* (2021). UniquePatterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells. Stem CellReports, 2021, 16(3): 458-469. IF: 6.63.

4.      Le, R.R.#,Huang, Y.X., Zhao, A.Q., and Gao, S.R.* (2020). Lessons from expanded potentialof embryonic stem cells: Moving toward totipotency. J Genet Genomics 47,123-130. IF: 5.065.

5.      Wu,L., Wu, Y., Peng, B., Hou, Z.Z., Dong, Y., Chen, K., Guo, M.Y., Li, H., Chen,X., Kou, X.C., Zhao, Y.H., Bi, Y., Wang, Y.X., Wang, H., Le, R.*, Kang, L.*, and Gao, S.R.* (2017). Oocyte-Specific Homeobox1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-EpithelialTransition and Mitigating Cell Hyperproliferation. Stem Cell Rep 9, 1692-1705.IF: 6.032.

6.      Chen, C., Liu, W.Q., Guo, J.Y., Liu, Y.Y., Liu, X.L., Liu,J., Dou, X.Y., Le, R.R., Huang,Y.X., Li, C., Yang, L.Y., Kou, X.C., Zhao, Y.H., Wu, Y., Chen, J.Y., Wang, H.,Shen, B., Gao, Y.W., Gao, S.R. (2021). Nuclear m6A reader YTHDC1 regulates thescaffold function of LINE1 RNA in mouse ESCs and early embryos (vol 12, pg 455,2021). Protein Cell. IF: 15

7.      Yang,Y.Y., Jiao, J., Gao, R., Le, R.R.,Kou, X.C., Zhao, Y.H., Wang, H., Gao, S.R., and Wang, Y.X. (2015). EnhancedRejuvenation in Induced Pluripotent Stem Cell-Derived Neurons Compared withDirectly Converted Neurons from an Aged Mouse. Stem Cells Dev 24, 2767-2777.IF: 3.082.

8.      Li,H., Gao, S., Huang, H., Liu, W., Huang, H., Liu, X., Gao, Y., Le, R.R., Kou, X., Zhao, Y., et al.(2017). High throughput sequencing identifies an imprinted gene, Grb10,associated with the pluripotency state in nuclear transfer embryonic stemcells. Oncotarget 8, 47344-47355. IF: 3.707.

9.      Qin,S.T., Yang, D.L., Chen, K., Li, H.L., Zhang, L.Q., Li, Y., Le, R.R., Li, X.J., Gao, S.R., and Kang, L. (2017). Pkm2 canenhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs.Oncotarget 8, 84276-84284. IF: 3.707.

10.   Zhang,Y.L., Zhao, L.W., Zhang, J., Le, R.R.,Ji, S.Y., Chen, C., Gao, Y.W., Li, D.L., Gao, S.R., and Fan, H.Y. (2018).DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability duringearly embryonic development. EMBO J 37. IF: 9.889.

11.   He,W.T., Zhang, X.B., Zhang, Y.L., Zheng, W.S., Xiong, Z.Y., Hu, X.J., Wang, M.Z.,Zhang, L.F., Zhao, K., Qiao, Z.B., Lai, W.Y., Lv, C., Kou, X.C., Zhao, Y.H.,Yin, J.Q., Liu, W.Q., Jiang, Y.H., Chen, M., Xu, R.M., Le, R.R., Li, C., Wang, H., Wan, X.P., Wang, H.L., Han, Z.M.,Jiang, C.Z., Gao, S.R., and Chen, J.Y. (2018). Reduced Self-Diploidization andImproved Survival of Semi-cloned Mice Produced from Androgenetic HaploidEmbryonic Stem Cells through Overexpression of Dnmt3b. Stem Cell Rep 10, 477.IF: 6.032.

Wang, C.F., Liu,X.Y., Gao, Y.W., Yang, L., Li, C., Liu, W.Q., Chen, C., Kou, X.C., Zhao, Y.H.,Chen, J.Y., Wang, Y.X., Le, R.R.,Wang, H., Duan, T., Zhang, Y., and Gao, S.R. (2018). Reprogramming ofH3K9me3-dependent heterochromatin during mammalian embryo development. Nat CellBiol 20, 620-631. IF: 20.042.