蒋颖副教授现有博士研究生2名，硕士研究生1名。

蒋颖副教授先后主持2项国家自然科学基金面上项目，1项国家自然科学基金青年项目，1项上海市面上项目，参与1项国家重点研发计划项目。

(1) 国家自然科学基金委员会, 面上项目, 32171288, 杜鹃素靶向UCHL3调控DNA修复的机制研究, 2022-01-01 至 2025-12-31, 58万元, 在研, 主持

(2) 国家自然科学基金委员会, 面上项目, 81972457, 去泛素化酶USP15在DNA双链断裂损伤修复中功能和分子机制的研究, 2020-01-01 至 2023-12-31, 55万元, 在研, 主持

1. Zhang W, Wang M, Song Z, Fu Q, Chen J, Zhang W, Gao S, SunX, Yang G, Zhang Q, Yang J, Tang H, Wang H, Kou X, Wang H, Mao Z*, Xu X*, GaoS*, Jiang Y*.Farrerol directly activates the deubiqutinase UCHL3 to promote DNArepair and reprogramming when mediated by somatic cell nuclear transfer. Nature Communications. 2023 Apr 3;14(1):1838. doi: 10.1038/s41467-023-37576-9. * Correspondingauthors.

2. Sun X,Tang H, Chen Y, Chen Z, Hu Z, Cui Z, Tao Y, Yuan J, Fu Y, Zhuang Z, He Q, Li Q,Xu X, Wan X, Jiang Y*, MaoZ*. Loss of ER/PR/HER2 promotes USP15-dependent stabilization ofPARP1 in triple-negative breast cancer. Nature Cancer. 2023 Apr3. doi: 10.1038/s43018-023-00535-w. *Corresponding authors. 

3. Zhang W, Yang J, Chen Y, Xue R, Mao Z*, Lu W*, Jiang Y*. Lycorine hydrochloridesuppresses stress-induced premature cellular senescence by stabilizing thegenome of human cells. Aging Cell. 2021 Feb;20(2):e13307. doi: 10.1111/acel.13307.* Corresponding authors.

4. Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, ChenY, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S,Jiang Y*, Sun FL*, Mao Z*. Rational combinationtherapy for hepatocellular carcinoma with PARP1 and DNA-PKcs inhibitors. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26356-26365. * Corresponding authors.

5. Chen Y, Zhang H, Xu Z, Tang H, GengA, Cai B, Su T, Shi J, Jiang C, Tian X, Seluanov A,Huang J, Wan X, Jiang Y*, Gorbunova V*, Mao Z*. A PARP1-BRG1-SIRT1 axis promotes HRrepair by reducing nucleosome density at DNA damage sites. Nucleic Acids Res. 2019 Sep 19;47(16):8563-8580. * Corresponding authors.

6. Chen Y, Cui Z, ChenZ, Jiang Y*, Mao Z*. IDDoR: A novel reporter mousesystem for simultaneous and quantitative in vivo analysis of both DNAdouble-strand break repair pathways. Protein & Cell. 2022 Oct 14. pwac001, https://doi.org/10.1093/procel/pwac001. *Corresponding authors.

7. Zhang F, Tang H, Jiang Y^*,Mao Z^*. The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression. Oncogene. 2017 Sep 7;36(36):5168-5176. doi: 10.1038/onc.2017.127. * Corresponding authors.

8. Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y^*,Mao Z^*.Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy. Cell Death & Disease. 2018 Mar 16;9(4):420. doi: 10.1038/s41419-018-0453-9. * Corresponding authors.