2012年起依托同济大学口腔医学院上海牙组织修复与再生工程技术中心，组建基础及临床研究团队。课题组已毕业博士10人，已毕业硕士25人。

  现研究团队由博士后、博士、硕士及技术人员等30余人组成，其中3人已获得国家自然科学基金青年项目资助。团队在硬组织发育矿化研究方面具有良好的研究经验和技术储备，实验涉及的动物模型完备，具备较好地开展各类实验的条件。

1. 自2018年以来，共获得国家自然科学基金项目4项（含优秀青年项目和区域联合重点项目），以及国家重点研发计划子课题1项。

2018年后：

1.     Li G#, Liu M#, Zhang S, Wan H, Zhang Q, Yue R, YanX, Wang X*, Wang Z*, Sun Y*. EssentialRole of IFT140 in Promoting Dentinogenesis. J Dent Res. 2018 97(4):423-431.

2.     Sun Y#*, Cai M#, Zhong J#, Yang L,Xiao J, Jin F, Xue H, Liu X, Liu H, Zhang Y, Jiang D, Hong A, Ji X, Wang Z*,Zhang G*, Wang X*. The long noncoding RNA lnc-ob1 facilitates bone formation byupregulating Osterix in osteoblasts. Nat Metab. 2019 1(4):485-496.

3.     Tao D#,Xue H, Zhang C, Li G, Sun Y*. The Role of IFT140 in Osteogenesis ofAdult Mice Long Bone. J Histochem Cytochem. 2019 67(8):601-611.

4.     Wei H#,Xu Y#, Wang Y#, Xu L, Mo C, Li L, Shen B, Sun Y,Cheng P, Yang L, Pang Y, Qin A, Cao Y, Morrison SJ, Yue R*. Identification ofFibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosisDrug Target. Cell Rep. 2020 13;33(2):108252.

5.     ZhangR#, Li J, Li G, Jin F, Wang Z, Yue R, Wang Y, Wang X*, Sun Y*.LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption.Int J Oral Sci. 20209;12(1):14.

6.     ChenY#, Fan Q, Zhang H, Tao D, Wang Y, Yue R, Sun Y*. Lineagetracing of cells expressing the ciliary gene IFT140 during bone development. DevDyn. 2021 250(4):574-583.

7.     Jin F#,Li J#, Zhang YB#, Liu X#, Cai M, Liu M, Li M,Ma C, Yue R, Zhu Y, Lai R, Wang Z, Ji X, Wei H, Dong J, Liu Z, Wang Y*, SunY*, Wang X*. A functional motif of long noncoding RNA Nron againstosteoporosis. Nat Commun. 2021 3;12(1):3319. 

8.      GongX, Zhang H, Xu X, Ding Y, Yang X, Cheng Z, Tao D, Hu C, Xiang Y, Sun Y*.Tracing PRX1+ cells during molarformation and periodontal ligament reconstruction.Int J Oral Sci. 2022 25;14(1):5.

9.   CaiM, Xiao B, Jin F, Xu X, Hua Y, Li J, Niu P, Liu M, Wu J, Yue R, Zhang Y,Wang Z, Zhang Y, Wang X, Sun Y. Generation of functionaloligopeptides that promote osteogenesis based on unsupervised deep learning ofprotein IDRs. Bone Res. 2022 1;10(1):23. 

10.   Y Ding , C Mo, J Geng, J Li, Y Sun.Identification of periosteal osteogenic progenitors in jawbone. J Dent Res. 2022 23; 220345221084200.  

11.   Mo C, Guo J, Qin J, Zhang X, Sun Y, Wei H,Cao D, Zhang Y, Zhao C, Xiong Y, Zhang Y, Sun Y, Shen L, Yue R. Single-celltranscriptomics of LepR-positive skeletal cells reveals heterogeneousstress-dependent stem and progenitor pools. EMBO J. 2022 Feb 15;41(4):e108415.

12.   Li J, Jin F, Cai M, Lin T, Wang X, Sun Y.LncRNA Nron Inhibits Bone Resorption in Periodontitis. J Dent Res.2022 Feb;101(2):187-195.

13.   Hu J, Li J, Jiang J, Wang L, Roth J, McGuinness KN,Baum J, Dai W, Sun Y, Nanda V, Xu F. Design of synthetic collagens thatassemble into supramolecular banded fibers as a functional biomaterial testbed.Nat Commun. 2022Nov 9;13(1):6761.

14.   Wang Y, Sun Y. Engineered organoids in oraland maxillofacial regeneration. iScience. 2022 Dec 7;26(1):105757.

15.   Zhang X, Zhou J, Wang X, Geng J, Chen Y, Sun Y.IFT140+/K14+ cells function as stem/progenitor cells in salivary glands. IntJ Oral Sci. 2022 Oct10;14(1):49.

16.   Ding, Y., Cai, M., Niu, P., Zhang, H., Zhang, S. Q.,& Sun, Y.. (2022). Ultrashortpeptides induce biomineralization. Composites, Part B. Engineering.

17.   Qiqi Fan, Xuekui Wang, Mengqi Zhou, Yubei Chen,Dike Tao, Songxi Rong, Shuang Zhou, Hui Xue, Yao Sun,Loss ofintraflagellar transport 140 in osteoblasts cripples bone fracture healing, FundamentalResearch,2022.

18.   Zhang H, Gong X, Xu X, Wang X, Sun Y. Toothnumber abnormality: from bench to bedside. Int J Oral Sci.2023 Jan 6;15(1):5.

19.   Tao D, Zhang L, Ding Y, Tang N, Xu X, Li G, Niu P,Yue R, Wang X, Shen Y, Sun Y. Primary cilia support cartilageregeneration after injury. Int J Oral Sci. 2023 Jun 2;15(1):22.

20.   Zhang F, Lv M, Wang S, Li M, Wang Y, Hu C, Hu W,Wang X, Wang X, Liu Z, Fan Z, Du J, Sun Y. Ultrasound-triggeredbiomimetic ultrashort peptide nanofiber hydrogels promote bone regeneration bymodulating macrophage and the osteogenic immune microenvironment. BioactMater. 2023 Aug 14;31:231-246.