2021年度“浦东新区卫生系统学科带头人培养计划”，2021.10-2025.09，30 万元，主持，在研。

国自然面上项目，81972830，靶向PLK1-NAC1调控通路治疗前列腺癌的机制研究，2020.1-2023.12，55万元，主持，在研。

江西省自然基金，20192BAB205066 ，PLK1磷酸化修饰NAC1在卵巢癌治疗中的研究，2019.1-2021.12，6万元，主持，已结题。

上海市“医苑新星”青年医学人才（临床检验项目）培养资助计划，2018.12-2021.12，10万元，主持，已结题。

国自然青年项目，81502381，USP39及其SUMO化修饰促进前列腺癌细胞增殖的作用机制研究，2016/01-2018/12，18万元，主持，已结题。

同济大学青年优秀人才培养行动计划，2015KJ075，去SUMO化修饰改变USP39细胞内定位对前列腺癌细胞功能影响的研究，2016/01-2017/12，2.5万元，主持，已结题

Li W, Wang Y, Guo W, Wen D. The status of p53 affects the efficacy of PLK1 inhibitor BI6727 in prostate cancer cells. Front Cell Dev Biol.2025 Jul 30:13:1602693. (共同通讯作者)

Wen D, Li W, Song X, Hu M, Liao Y, Xu D, Deng J, Guo W.NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer.Cell Death Dis. 2025 Feb 22;16(1):124.(共同第一作者)

Yan Y, Wang L, Zhong N, Wen D, Liu L.Multifaced roles of adipokines in endothelial cell function.Front Endocrinol (Lausanne). 2024 Nov 4;15:1490143.(共同通讯作者)

Wen,D.; Hu, M.; Guo, W.; Wu, J.; Wu, Y., Multi-SUMOylation of NAC1 is essentialfor the growth of prostate cancer cells. Biochemicaland biophysical research communications 2023, 641, 148-154. (共同第一作者和共同通讯作者)

Wen, D.; Yang, S.; Li, G.; Xuan, Q.;Guo, W.; Wu, W., Sample-to-Answer and Routine Real-Time RT-PCR: A Comparison ofDifferent Platforms for SARS-CoV-2 Detection. The Journal of molecular diagnostics : JMD 2021, 23 (6), 665-670.(共同第一作者)

Lin, Q.; Wen, D.; Wu, J.; Liu, L.;Wu, W.; Fang, X.; Kong, J., Microfluidic Immunoassays for Sensitive andSimultaneous Detection of IgG/IgM/Antigen of SARS-CoV-2 within 15 min. Analytical chemistry 2020, 92 (14), 9454-9458. (共同第一作者)

Huang, W.; Yu, L.; Wen, D.; Wei, D.;Sun, Y.; Zhao, H.; Ye, Y.; Chen, W.; Zhu, Y.; Wang, L.; Wang, L.; Wu, W.; Zhao,Q.; Xu, Y.; Gu, D.; Nie, G.; Zhu, D.; Guo, Z.; Ma, X.; Niu, L.; Huang, Y.; Liu,Y.; Peng, B.; Zhang, R.; Zhang, X.; Li, D.; Liu, Y.; Yang, G.; Liu, L.; Zhou,Y.; Wang, Y.; Hou, T.; Gao, Q.; Li, W.; Chen, S.; Hu, X.; Han, M.; Zheng, H.;Weng, J.; Cai, Z.; Zhang, X.; Song, F.; Zhao, G.; Wang, J., ACRISPR-Cas12a-based specific enhancer for more sensitive detection ofSARS-CoV-2 infection. EBioMedicine 2020, 61, 103036. (共同第一作者)

Guo, W.; Kuang, Y.; Wu, J.; Wen, D.;Zhou, A.; Liao, Y.; Song, H.; Xu, D.; Wang, T.; Jing, B.; Li, K.; Hu, M.; Ling,J.; Wang, Q.; Wu, W., Hexokinase 2 Depletion Confers Sensitization to Metforminand Inhibits Glycolysis in Lung Squamous Cell Carcinoma. Frontiers in oncology 2020,10, 52. (共同第一作者)

Guo, W.; Hu, M.; Wu, J.; Zhou, A.; Liao, Y.; Song, H.; Xu, D.; Kuang, Y.; Wang,T.; Jing, B.; Li, K.; Ling, J.; Wen, D.;Wu, W., Gprc5a depletion enhances the risk of smoking-induced lungtumorigenesis and mortality. Biomedicine& pharmacotherapy = Biomedecine & pharmacotherapie 2019, 114, 108791.(共同通讯作者)

Jingjing, W.; Wenzheng, G.; Donghua, W.;Guangyu, H.; Aiping, Z.; Wenjuan, W., Deubiquitination and stabilization ofprogrammed cell death ligand 1 by ubiquitin-specific peptidase 9, X-linked inoral squamous cell carcinoma. Cancer medicine 2018, 7 (8), 4004-4011. (共同第一作者)

Wen, D.; Wu, J.; Wang, L.; Fu, Z.,SUMOylation Promotes Nuclear Import and Stabilization of Polo-like Kinase 1 toSupport Its Mitotic Function. Cell reports 2017, 21 (8), 2147-2159. (共同第一作者)

Wen, D.; Xu, Z.; Xia, L.; Liu, X.; Tu,Y.; Lei, H.; Wang, W.; Wang, T.; Song, L.; Ma, C.; Xu, H.; Zhu, W.; Chen, G.;Wu, Y., Important role of SUMOylation of Spliceosome factors in prostate cancercells. Journal of proteome research 2014, 13 (8), 3571-82. (共同第一作者)

Chen, Y.; Wen, D.; Huang, Z.; Huang, M.; Luo, Y.; Liu, B.; Lu, H.; Wu, Y.;Peng, Y.; Zhang, J., 2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoatederivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesisand biological evaluation. Bioorganic& medicinal chemistry letters 2012,22 (22), 6867-70. (共同第一作者)