1、国家自然科学基金面上项目：基于近红外光的恶性肿瘤的早期诊断和治疗，2022.1-2025.12，58万，在研，主持

2、2023年度市级医院诊疗技术推广及优化管理项目：基于AI技术的多模态大数据赋能肺癌放疗能力建设与推广研究，2023.6.1-2025.5.31，40万，在研，主持

3、上海医学创新发展基金会：上海市肺癌的综合诊治路径建设SOP项目，2022.11-2024.12，5万，在研，主持

4、上海市科委自然基金：脓肿分支杆菌GPL基因突变通过触发铁自噬诱导的巨噬细胞铁死亡导致菌体毒力增强的机制研究，2020.1-2022.12，20万，已结题，主持

5、上海市科委西医引导项目：基于核酸质谱的MassARRAY细菌核酸指纹新技术用于分枝杆菌肺病的精确诊断， 2019.8-2022.9，20万，已结题，主持

1、国家自然科学基金面上项目：基于近红外光的恶性肿瘤的早期诊断和治疗，2022.1-2025.12，58万，在研，主持

2、2023年度市级医院诊疗技术推广及优化管理项目：基于AI技术的多模态大数据赋能肺癌放疗能力建设与推广研究，2023.6.1-2025.5.31，40万，在研，主持

3、上海医学创新发展基金会：上海市肺癌的综合诊治路径建设SOP项目，2022.11-2024.12，5万，在研，主持

4、上海市科委自然基金：脓肿分支杆菌GPL基因突变通过触发铁自噬诱导的巨噬细胞铁死亡导致菌体毒力增强的机制研究，2020.1-2022.12，20万，已结题，主持

5、上海市科委西医引导项目：基于核酸质谱的MassARRAY细菌核酸指纹新技术用于分枝杆菌肺病的精确诊断， 2019.8-2022.9，20万，已结题，主持

代表性论著

1.      Bing Li, Siyuan He, Zhili Tan, Anqi Li, JunshengFan, Lan Zhao, Zhemin Zhang, Haiqing Chu. Impaired ESX-3 Induces BedaquilinePersistence in Mycobacterium abscessus Growing Under Iron-limited Conditions.Small Methods. 2023 Jun 8:e2300183. doi: 10.1002/smtd.202300183. Epub ahead ofprint. PMID: 37291735.

2.      Zhang SJ, Yang Y, Sun WW, Zhang ZS, Xiao HP, Li YP,Zhang ZM, Fan L. Effectiveness and safety of bedaquiline-containing regimensfor treatment on patients with refractory RR/MDR/XDR-tuberculosis: aretrospective cohort study in East China. BMC Infect Dis. 2022 Aug29;22(1):715. doi: 10.1186/s12879-022-07693-9. PMID: 36038829; PMCID:PMC9422092.

3.      Ding J, Jiang H, SuB, Wang S, Chen X, Tan Y, Shen L, Wang J, Shi M, Lin H, Zhang Z.DNMT1/miR-130a/ZEB1 Regulatory Pathway Affects the Inflammatory Response inLipopolysaccharide-Induced Sepsis. DNA Cell Biol. 2022 May;41(5):479-486. doi:10.1089/dna.2021.1060. Epub 2022 Apr 29. PMID: 35486848.

4.      Sun W, Dong Z, Zhou Y, Xiong K, Liu H, Zhang Z, FanL. Early Identification of Fungal and Mycobacterium Infections in PulmonaryGranulomas Using Metagenomic Next-Generation Sequencing on Formalin fixationand paraffin embedding tissue. Expert Rev Mol Diagn. 2022 Apr;22(4):461-468.doi: 10.1080/14737159.2022.2052046. Epub 2022 Mar 15. PMID: 35261303.

5.      Sun H, Dai J, ZhaoL, Zhu J, Wang H, Chen P, Lu H, Chen Q, Zhang Z. Lymphocyte activation gene-3is associated with programmed death-ligand 1 and programmed cell death protein1 in small cell lung cancer. Ann Transl Med. 2021 Sep;9(18):1468. doi:10.21037/atm-21-4481. PMID: 34734020; PMCID: PMC8506769.

6.       Shi J, Li J,Wang Q, Cheng X, Du H, Han R, Li X, Zhao C, Gao G, He Y, Chen X, Su C, Ren S,Wu F, Zhang Z, Zhou C. The safety and efficacy of immunotherapy withanti-programmed cell death 1 monoclonal antibody for lung cancer complicatedwith Mycobacterium tuberculosis infection. Transl Lung Cancer Res. 2021Oct;10(10):3929-3942. doi: 10.21037/tlcr-21-524. PMID: 34858782; PMCID:PMC8577979.

7.      Sun W, Zhou Y, Li W,Wang Y, Xiong K, Zhang Z, Fan L. Diagnostic yield of Xpert MTB/RIF oncontrast-enhanced ultrasound-guided pleural biopsy specimens for pleuraltuberculosis. Int J Infect Dis. 2021 Jul;108:89-95. doi:10.1016/j.ijid.2021.05.023. Epub 2021 May 14. PMID: 33992762.

8.      Sun W, Zhou Y, YangC, Dong Z, Zhang Z, Wang Y, Fan L. Contrast-enhanced ultrasound guided pleuralbiopsy improves diagnostic confidence for pleural based lesions: a 3-yearprospective study. BMC Pulm Med. 2021 Jul 12;21(1):224. doi:10.1186/s12890-021-01583-7. PMID: 34247611; PMCID: PMC8274055.

9.      Wei Yin, Junjie Zhu, Benting Ma, Gening Jiang,Yuming Zhu , Wei He , Yang Yang, Zhemin Zhang. Overcoming Obstacles inPathological Diagnosis of Pulmonary Nodules through Circulating Tumor CellEnrichment. Small. 2020 Jun;16(25):e2001695. doi: 10.1002/smll.202001695. Epub2020 May 26.

10.   Bing Li, Qi Guo, Yanhua Mao, Yuzhen Zou, YongjieZhang, Zhemin Zhang, Haiqing Chu, Genetic Evolution of Mycobacterium abscessusConferring Clarithromycin Resistance During Long-term Antibiotic Therapy,Canadian Respiratory Journal,2020, Article ID 7623828

11.   Mingyan Wua, Bing Li, Qi Guoa, Liyun Xu, YuzhenZou, Yongjie Zhang, Mengling Zhan, Benyong Xu, Meiping Ye, Fangyou Yu, ZheminZhang, Haiqing Chu. Detection and Molecular Characterization ofAmikacin-resistant Mycobacterium abscessus Isolated from Patients withPulmonary Disease. Journal of Global Antimicrobial Resistance. 2019 May 20.pii: S2213-7165(19)30126-2.

12.   Lin Fan, Danfeng Li, Shaojun Zhang, Lan Yao,Xiaohui Hao, Jin Gu, Hong Li, Jinxia Niu, Zhemin Zhang, Changtai Zhu. ParallelTests Using Culture, Xpert MTB/RIF, and SAT-TB in Sputum Plus BronchialAlveolar Lavage Fluid Significantly Increase Diagnostic Performance ofSmear-Negative Pulmonary Tuberculosis. Front Microbiol. 2018 Jun 15;9:1107.doi: 10.3389/fmicb.2018.01107. eCollection 2018.

13.   Weijia Liu, Bing Li, Haiqing Chu, Zhemin Zhang,Liulin Luo, Wei Ma, Shiyi Yang, Qi Guo. Rapid Detection of Mutations in erm(41)and rrl Associated with Clarithromycin Resistance in Mycobacterium abscessusComplex by Denaturing Gradient Gel Electrophoresis. Journal of MicrobiologicalMethods. 2017, 143:87–93.

14.   Bing Li, Shiyi Yang, Haiqing Chu, Zhemin Zhang,Weijia Liu, Liulin Luo, Wei Ma, Xiaogang Xu. Relationship between antibioticsusceptibility and genotype in Mycobacterium abscessus clinical isolates.Frontiers in Microbiology. 2017,8(1739)

15.   Liu Yinan, Sun Hui, Zhou Fei, Su Chunxia, GaoGuanghui, Ren Shengxiang, Zhou Caicun, Zhang Zhemin, Shi Jingyun. Imagingfeatures of TSCT predict the classification of pulmonary preinvasive lesion,minimally and invasive adenocarcinoma presented as ground glass nodules. LungCancer. 2017.108:192-197.

16.   Luo L, Liu W, Li B, Li M, Huang D, Jing L, Chen H,Yang J, Yue J, Wang F, Chu H, Zhang Z. Evaluation of Matrix-Assisted LaserDesorption Ionization-Time of Flight Mass Spectrometry for Identification ofMycobacterium abscessus Subspecies According to Whole-Genome Sequencing. J ClinMicrobiol. 2016 Dec;54(12):2982-2989. doi: 10.1128/JCM.01151-16. Epub 2016 Sep28. PMID: 27682129; PMCID: PMC5121389.

成果著作

1.      介入支气管镜临床指南   2017-04出版 上海科学技术出版社 主译

2.      临床结核病营养学 2022-06出版 科学出版社 主编