个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
医学博士，主任医师，教授，博士及博士后导师，同济大学附属养志康复医院心肺及重症康复中心主任，麻醉科及疼痛科主任。美国纽约特种外科医院访问学者，荣获上海市医务工匠，上海市巾帼建功标兵等称号。担任中国康复医学会疼痛专委会常务委员、中国心胸血管麻醉疼痛学分会常务委员、中国心胸血管麻醉围术期康复分会常务委员、中国医促会区域麻醉与疼痛分会常务委员等。主要研究方向为连续神经阻滞麻醉及疼痛治疗；神经调控技术及神经病理性疼痛机制研究等。主持国家自然科学基金面上项目2项、上海科委创新项目3项及上海申康、卫计委等项目8项，发表论著40余篇，获批专利16项，转化专利6项，转化专利产品获国家医疗器械三类证及医保代码，独创的连续神经阻滞麻醉及术后镇痛技术已推广至全国多家医院造福众多患者；获上海医学科技三等奖及康复科技成果二等奖各一项（第一获奖人）。
Professor,chief physician, and doctoral/postdoctoral supervisor at the YangzhiRehabilitation Hospital, affiliated with Tongji University. He is also theDirector of the Cardio-Pulmonary and Critical Care Rehabilitation Center, aswell as the Department of Anesthesiology and Pain Management. He is anaccomplished researcher, specializing in continuous nerve block anesthesia,pain management, neurostimulation, and neuropathic pain mechanisms. Dr. [Name]has led multiple National Natural Science Foundation and Shanghai innovationprojects, published over 40 articles, and holds 16 patents. His patentedtechnologies have been successfully translated into clinical practice acrossmany hospitals, benefiting numerous patients. He has received severalprestigious awards, including the Shanghai Medical Science and Technology ThirdPrize and the Rehabilitation Technology Second Prize.
主持纵向科研项目（项目负责人）
1.2020年上海市同济医院专利转化孵化基金
【一次性使用连续外周阻滞套件】资助金额10万元，结题
2. 2019年国家自然基金项目（批准号 81974167）
【高频电场抑制神经异常放电缓解神经病理性疼痛机制研究】资助金额55万元，在研
3. 2018年上海市科委项目（编号18441905700）
【用于外周神经传导阻滞的新型高频电刺激仪及配套刺激电极的研制】资助金额35万元，结题
4. 2018年同济大学“中央高校基本科研业务费专项资金” （编号22120180417）
【高频电刺激通过CaMII信号通路致Nav1.8通道失活治疗神经病理性疼痛机制研究】资助金额5万元，结题
5. 2017年上海市申康促进市级医院临床技能与临床创新三年行动计划的科研项目（批准号 16CR3004A）
【单肢区域麻醉及镇痛新技术在老年髋关节置换术中的临床研究及推广应用】资助金额50万元，结题
6. 2015年上海科委医学引导类（中、西医）科技项目（编号 15411965600）
【神经阻滞量化模型的建立及临床应用研究】资助金额20万元，结题
7. 2013年上海市卫生系统先进适宜技术推广项目（编号2013SY032）
【国产神经阻滞针及其引导的术后镇痛技术推广应用】资助金额50万元，结题
8. 2012年上海市卫生局资助课题（编号20124362）
【国产外周神经阻滞留置针在全膝关节置换术中的应用研究】资助金额3万元，结题
主持横向科研项目（受申办方企业委托作为牵头单位发起的器械注册研究）
【连续外周神经阻滞套件在骨科上下肢术后镇痛的有效性和安全性研究----多中心、单盲、随机、阳性器械平行对照临床试验】资助金额40万元，在研，多中心组长单位，项目负责人。
1. 市级医院新兴前沿联合攻关项目（编号SHDC12024147）【连续神经阻滞单肢麻醉和术后镇痛临床技术评价及在骨科一体化快速康复中应用】研究经费15万元，在研，主持（Municipal HospitalJoint Frontier Project, Clinical evaluation of single-limb anesthesia andpostoperative analgesia through continuous nerve block in orthopedic integratedrapid rehabilitation,）
2. 上海市2023年度“科技创新行动计划”项目（编号23Y190650）【超声引导单肢区域神经阻滞麻醉及镇痛技术降低老年髋部骨折患者术后并发症的真实世界研究：一项前瞻性、多中心、队列研究】研究经费30万元，在研，主持（2023 Shanghai"Science and Technology Innovation Action Plan" Project, Real-worldstudy on ultrasound-guided single-limb regional nerve block anesthesia andanalgesia techniques to reduce postoperative complications in elderly patientswith hip fractures: A prospective, multicenter cohort study）
3. 养志康复医院2024年院内重点项目（编号2024CRZD010）【千赫兹交流电刺激选择性调控迷走神经改善PD神经退行性变机制研究】研究经费30万元，在研，主持（2024 Key Project ofYangzhi Rehabilitation Hospital, Study on selective regulation of vagus nerveby kilohertz alternating current stimulation to improve neurodegenerativechanges in PD,）
4. 国家自然科学基金面上项目（批准号82471242）【千赫兹交流电刺激通过原钙粘蛋白调控5-羟色胺能通路缓解神经病理性疼痛的机制研究】研究经费49万元，在研，主持（General Project of theNational Natural Science Foundation of China, Study on the mechanism ofkilohertz alternating current stimulation alleviating neuropathic pain throughprotocadherin-mediated regulation of serotonergic pathways）
1.Fang, K., Cheng,W. & Yu, B. (2024). Effects of Electroacupuncture at Varied Frequencies onAnalgesia and Mechanisms in Sciatic Nerve Cuffing-Induced Neuropathic PainMice. J Mol Neurosci 74, 98.
2.Cheng, W., Fang,K., Ouyang, X., Jin, L., Song, Y., & Yu, B. (2024). Vagus nerve stimulationwith a small total charge transfer improves motor behavior and reducesneuroinflammation in a mouse model of Parkinson's disease. Neurochemistryinternational, 180, 105871. Advance online publication.
3.Fang K, Lu P,Cheng W, Yu B. Kilohertz high-frequency electrical stimulation amelioratehyperalgesia by modulating transient receptor potential vanilloid-1 andN-methyl-D-aspartate receptor-2B signaling pathways in chronic constrictioninjury of sciatic nerve mice. Mol Pain. 2024;20:17448069231225810
4.Peixin Lu, KexinFang，Wen Cheng , Bin Yu* . High-frequencyelectrical stimulation reduced hyperalgesia and the activation of the Myd88 andNFκB pathways in chronic constriction injuryof sciatic nerve-induced neuropathic pain mice. Neurosci Lett.2023;796:137064.
5.Peixin Lu, WenCheng , Kexin Fang ,Bin Yu* . Multidimensional study of CDCA family members ingastric carcinoma with prognostic value[J]. Bosn J of Basic Med Sci .2022.22（1）：64-76.
6.XiaoruiChen,Dandan Ling,Jianfang Cao,Xiaoyan Lin,Xiaodan Cao,Mengying Wang,JunjieLuo,Shuqi Xie,Bin Yu*.Factors Associated with Minimum Effective Volume ofLidocaine 1.5% for Sciatic Nerve Blocks[J]. The Clinical Journal ofPain.2020,36(4):296-301.
7.Junjie Luo,Guangyu Cai,Dandan Ling,Na Zhang,Xiaorui Chen,XiaodanCao,Bin Yu*.Mean effective volume of local anesthetics by nerve conductiontechnique[J]. Annals of translational medicine.2020,8(5):174-182.
文件上传中...
同济大学