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同济大学教授,主任医师,博士生导师,附属第十人民医院重症医学科科主任。兼任中国医师协会重症医学医师分会委员,中国老年医学学会重症医学分会常务委员,中国医药卫生事业发展基金会重症医学专委会副主任委员,中华医学会肠内肠外营养分会重症营养学组委员,上海中医药学会危重病分会副主任委员,上海医学会危重病专业委会委员,上海医师协会重症医学医师分会委员。Journal of Emergency and Critical Care Medicine 杂志及中华重症医学杂志编委,国家自然科学基金、教育部留学归国人员基金和上海市科委课题评审专家,上海市急诊危重病专业高级职称评审专家;上海市浦江人才计划和上海卫生系统青年人才“银蛇奖”获得者,上海市优秀共产党员。擅长重症营养,重症感染的综合救治及体外心肺支持技术(ECMO),所在实验室2023年获批病原体与宿主相互作用教育部重点实验室。先后主持包括国家自然科学基金在内的各级课题近20项,发表论著70余篇,SCI收录论文40余篇。
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支持扩展名:.rar .zip .doc .docx .pdf .jpg .png .jpeg1. 上海市公共卫生体系建设三年行动计划(GWV-3.1),上海市感染病临床诊治中心及其网络体系建设,1000万元(121万元),区域中心负责人
2. 申康“促进市级医院临床技能与临床创新能力三年行动计划”(SHDC2020CR6030)临床研究关键支撑项目,全生命周期脓毒血症专病队列数据库建设, 37.4万元,负责人
3. 申康“促进市级医院临床技能与临床创新能力三年行动计划”重大临床研究项目(SHDC2020CR1028B):基于医院信息系统脓毒症快速精准诊断方法的建立与应用的多中心临床研究,700万元(50万元),分中心负责人
4. 申康“促进市级医院临床技能与临床创新能力三年行动计划”新兴前沿技术联合攻关项目(SHDC12020122):免疫细胞导向的临床外表型指导脓毒症患者治疗的多中心临床研究,100万元(15万元),子课题负责人
5. 国家自然科学基金面上项目(81871540):lncRNA GAS5调控自噬在脓毒症性心肌损伤中的作用,57万元,负责人
1. Comparative venom multi-omics reveal the molecular mechanisms driving adaptation to diverse predator-prey ecosystems in closely related sea snakes. Mol Biol Evol 2023; 40(6): msad125. IF 10.8
2. Discovery of an anti-TNF-α 9-mer peptide from a T7 phage display library for the treatment of inflammatory bowel disease. J Medical Chemistry 2023; 66 (10): 6981–6993. IF 8.04
3. Identification of autophagy-related genes and immune cell infiltration characteristics in sepsis via bioinformatic analysis. J Thorac Dis 2023;15(4):1770-1784. IF 3.01
4. Identification of iron metabolism-related genes in the circulation and myocardium of patients with sepsis via applied bioinformatics analysis. Front Cardiovasc Med. 2023, 10: 1018422. IF 5.85
5. Effect of partially hydrolyzed guar gum on the composition and metabolic function of the intestinal flora of healthy mice. Journal of Food Biochemistry, 2022, 46(12):1-15. IF 3.65
6. Study on the mechanism of Fentanyl in pain treatment based on network pharmacology. Journal of Healthcare Engineering 2022; 2022: 4139200. IF 3.82
7. The species identification and genomic analysis of Haemobacillus shengwangii: A novel pathogenic bacterium isolated from a critically ill patient with bloodstream infection. Front Microbiol 2022; 13: 919169. IF 6.06
8. The genomic characterization of KPC-producing klebsiella pneumoniae from the ICU of a teaching hospital in Shanghai, China. Infection and Drug Resistance 2022; 15: 69–81. IF 4.18
9. Two reference-quality sea snake genomes reveal their divergent evolution of adaptive traits and venom systems. Mol Biol Evol 2021; 38 (11): 4867–4883. IF 16.24
10. Profiles of differentially expressed long noncoding RNAs and messenger RNAs in the myocardium of septic mice, Ann Transl Med 2021; 9(3): 199. IF 3.93
11. A comparison of the delivery of inhaled drugs by jet nebulizer and vibrating mesh nebulizer using dual-source dual-energy computed tomography in rabbits: a preliminary in vivo study. Ann Transl Med 2020; 8(17): 1072. IF 3.93
12. Early warning indicators of severe COVID-19: A single-center study of cases from Shanghai, China. Front. Med. 2020; 7: 432. IF 5.09
13. An improved two-step method for extraction and purification of primary cardiomyocytes from neonatal mice. J Pharmacol Toxicol Methods 2020; 104: 106887. IF 2.68
14. Anti-inflammatory activity and mechanism of hydrostatin-SN1 from hydrophis cyanocinctus in interleukin-10 knockout mice. Front. Pharmacol. 2020; 11: 930. IF 5.86
15. Long non-coding RNA GAS5 inhibits migration and invasion in gastric cancer via interacting with p53 protein. Digestive and Liver Disease 2020; 52(3): 331-338. IF 4.09

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