现担任上海市肺科医院胸外科科室副主任，科室团队现有正高一人，主治一人，住院医师一人。团队擅长各类肺部良性疾病、肺恶性肿瘤、气管、纵隔、胸膜疾病的外科治疗，各类胸腔镜和纵隔镜手术，气胸及肺大疱的外科治疗，尤其擅长气管肿瘤、气管良性狭窄的外科治疗以及单孔胸腔镜复杂肺叶和肺段切除术。

课题组现有在读博士研究生三名，硕士研究生1名，主要聚焦于气管组织工程和肺癌的发生发展的相关研究。在气管组织工程研究领域，提出采用激光打孔技术，实现了具有足够力学强度的新生气管，通过胶原修饰气管激光打孔脱细胞基质，不但显著提高了细胞接种率，而且实现了均质厚实的气管软骨再生；提出环状构建理念以构建高仿生气管组织，并成功进行长段缺损修复动物模型效果评估。肺癌研究领域，主要针对非小细胞肺癌的化疗耐药和免疫抑制方向进行相关分子机制研究。

1.      科技部国家重点研发计划，2024YFA1107800，软骨-纤维-上皮仿生气管再生及气管缺损修复大动物临床前研究，2024/12-2027/11，经费180万元，在研，子课题负责人

2.      国家自然科学基金重点项目，32430060，多类型细胞精准适配长段气管仿生构建及大动物气管缺损功能重建，2025/01-2029/12，经费215万元，在研，子课题负责人

3.      上海市自然科学基金，22ZR1452100，模块化C形软骨构建的仿生气管用于羊长段气管缺损修复效果的研究，2022/04-2025/03，经费20万，在研，主持

4.      国家自然科学基金面上项目，81970014，高仿生组织工程气管的构建及修复长段气管缺损的实验研究，2020/01-2023/12，经费55万元，结题，主持

5.      上海市自然科学基金，19ZR1442600，高仿生组织工程气管预构建及长段气管缺损修复，2019/07-2022/06，经费20万元，结题，主持

6.      国家自然科学基金面上项目，81570089，生物压膜上皮种植技术促进带蒂大网膜包裹脱上皮细胞同种异体气管移植再上皮化的实验研究，2016/01-2019/12，经费60万元，已结题，第二负责人

7.      国家自然科学基金面上项目，81270070，激光微孔气管脱细胞基质的制备及构建兔组织工程气管管状软骨的实验研究，2013/01-2016/12，经费60万元，已结题，主持

8.      上海市自然科学基金，12ZR1425800，激光微孔气管脱细胞基质的制备及构建组织工程管状软骨修复气管节段性缺损，2012/09-2015/08，经费10万元，已结题，主持

9.      上海市卫生局课题，同种异体气管脱细胞基质的制备及构建组织工程气管管状软骨的实验研究， 2012/01-2013/12，经费3万元，已结题，主持

1.      上海市自然科学基金，22ZR1452100，模块化C形软骨构建的仿生气管用于羊长段气管缺损修复效果的研究，2022/04-2025/03，经费20万，在研，主持

2.      国家自然科学基金面上项目，81970014，高仿生组织工程气管的构建及修复长段气管缺损的实验研究，2020/01-2023/12，经费55万元，在研，主持

3.      上海市自然科学基金，19ZR1442600，高仿生组织工程气管预构建及长段气管缺损修复，2019/07-2022/06，经费20万元，在研，主持

4.      国家自然科学基金面上项目，81570089，生物压膜上皮种植技术促进带蒂大网膜包裹脱上皮细胞同种异体气管移植再上皮化的实验研究，2016/01-2019/12，经费60万元，已结题，第二负责人

5.      国家自然科学基金面上项目，81270070，激光微孔气管脱细胞基质的制备及构建兔组织工程气管管状软骨的实验研究，2013/01-2016/12，经费60万元，已结题，主持

6.      上海市自然科学基金，12ZR1425800，激光微孔气管脱细胞基质的制备及构建组织工程管状软骨修复气管节段性缺损，2012/09-2015/08，经费10万元，已结题，主持

7.      上海市卫生局课题，同种异体气管脱细胞基质的制备及构建组织工程气管管状软骨的实验研究， 2012/01-2013/12，经费3万元，已结题，主持

1.       Xiang Li, Qiuyuan Li, Fujun Yang, Erji Gao, Lei Lin, Yaqiang Li, Xiao Song, LiangDuan. Neoadjuvant therapy does not increase postoperative morbidity ofsleeve lobectomy in locally advanced non-small cell lung cancer. JThorac Cardiovasc Surg. 2023, S0022-5223(23):00254-4.

2.       ErjiGao, Yao Wang, Pengli Wang, Qianyi Wang, Yuxuan Wei, Daiying Song, HuangfangXu, Jinghao Ding, Yong Xu, Huitang Xia, Ru Chen, and Liang Duan.C-Shaped Cartilage Development Using Wharton's Jelly-Derived Hydrogels toAssemble a Highly Biomimetic Neotrachea for use in Circumferential TrachealReconstruction. Advanced Functional Materials. 2023, 2212830:1-17.

3.       ErjiGao, Pengli Wang, Feifan Chen, Yong Xu, Qianyi Wang, Hong Chen, Gening Jiang,Guangdong Zhou, Dan Li, Yi Liu, Liang Duan. Skin-derived epithelial liningfacilitates orthotopic tracheal transplantation by protecting the trachealcartilage and inhibiting granulation hyperplasia. Biomaterials Advances,2022,139:213037.

4.       PengliWang, Gaoran Xu, Erji Gao, Yong Xu, Leilei Liang, Gening Jiang, Liang Duan.Identification of Prognostic DNA Methylation Signatures in Lung Adenocarcinoma.Oxidative Medicine and Cellular Longevity, 2022:8802303.

5.       ErjiGao, Gao Li, Runfeng Cao, Huitang Xia, Yong Xu, Gening Jiang, Kaiyan Xiao, JieChen, Ru Chen, Liang Duan. Bionic tracheal tissue regeneration using aring-shaped scaffold comprised of decellularized cartilaginous matrix and silkfibroin. Composites Part B: Engineering, 2022, 229: 109470.

6.       JinghanShi, Fei Li, Fujun Yang, Zhengwei Dong, Yan Jiang, Dania Nachira, JustynaChalubinska-Fendler, Terence T. Sio, Yo Kawaguchi, Hiromitsu Takizawa, XiaoSong, Yang Hu, Liang Duan. The combination of computed tomographyfeatures and circulating tumor cells increases the surgical prediction ofvisceral pleural invasion in clinical T1N0M0 lung adenocarcinoma. TranslationalLung Cancer Research, 2021,10(11): 4266-4280.

7.       YongYang, Shaojun Zhang, Zhengwei Dong, Yong Xu, Xuefei Hu, Gening Jiang, Lin Fanand Liang Duan. Sublobectomy is a safe alternative for localizedcavitary pulmonary tuberculosis. Journal of Cardiothoracic Surgery, 2021,16(1):22.

8.       XuYong, Guo Yifan, Li Yaqiang, Huo Yingying, She Yunlang, Li Hao, Jia Zihao,Jiang Gening, Zhou GuangDong, You Zhengwei, and Duan Liang. BiomimeticTrachea Regeneration Using a Modular Ring Strategy Based on Poly(SebacoylDiglyceride)/Polycaprolactone for Segmental Trachea Defect Repair. AdvancedFunctional Materials,2020,30(42): 2004276.

9.       XuYong, She Yunlang, Li Yaqiang, Li Hao, Jia Zihao, Jiang Gening, Liang Leilei,and Duan Liang. Multi-omics analysis at epigenomics and transcriptomicslevels reveals prognostic subtypes of lung squamous cell carcinoma. Biomedicine& Pharmacotherapy,2020,125: 109859.

10.    Xu Yong, Li Yaqiang, LiuYanqun, Li Hao, Jia Zihao, Tang Yao, Jiang Gening, Zhang Xue, and Duan Liang.Surface modification of decellularized trachea matrix with collagen and lasermicropore technique to promote cartilage regeneration. American Journal ofTranslational Research,2019,11(9):5390-5403.

11.    Li Yaqiang, Xu Yong, LiuYanqun, Wang Zongxin, Chen Weiming, Duan Liang, and Gu Dongyun.Decellularized cartilage matrix scaffolds with laser-machined micropores forcartilage regeneration and articular cartilage repair. Materials Science &Engineering C-Materials for Biological Applications, 2019,105: 110139.

12.    Hu Xuefei, Duan Liang,Liu Hongcheng, and Zhang Lei. Long noncoding RNA LINC01296 induces non-smallcell lung cancer growth and progression through sponging miR-5095. AmericanJournal of Translational Research,2019,11(2):895-903.

13.    Song Nan, Duan Liang,Fang Zhiyong, Jiang Gening. Uniportal video-assisted thoracoscopic left S4anatomical segmentectomy. Thoracic Cancer, 2019, 10: 1248-1251.

14.    Zhang Yongjun, Xu Yong,Liu Yanqun, Li Dan, Yin Zongqi, Huo Yingying, Jiang Gening, Yang Yong, Wang Zongxin,Li Yaqiang, Lu Fangjia, Liu Yi, Duan Liang, and Zhou Guangdong. Porousdecellularized trachea scaffold prepared by a laser micropore technique.Journal of the Mechanical Behavior of Biomedical Materials,2019,90:96-103.

15.    Duan Liang, Jiang Gening, and YangYong. One hundred and fifty-six cases of anatomical pulmonary segmentectomy byuniportal video-assisted thoracic surgery: a 2-year learning experience.European Journal of Cardio-Thoracic Surgery,2018,54(4):677-682.

16.    Xu Yong, Li Dan, Yin Zongqi,He Aijuan, Lin Mingming, Jiang Gening, Song Xiao, Hu Xuefei, Liu Yi, Wang Jinpeng,Wang Xiaoyun, Duan Liang, and Zhou Guangdong. Tissue-engineered trachearegeneration using decellularized trachea matrix treated with laser microporetechnique. Acta Biomaterialia,2017,58:113-121.

17.    Duan Liang, Hu Xuefei, Jin Yuxing,Liu Ruijing, and You Qingjun. Survivin protein expression is involved in theprogression of non-small cell lung cancer in Asians: a meta-analysis. BMCCancer,2016,16: 276.

18.    Duan Liang, Chen Xiaofeng, Wang Hao,Hu Xuefei, and Jiang Gening. Surgical treatment of late-diagnosed bronchialforeign body aspiration: a report of 23 cases. Clinical RespiratoryJournal,2014,8(3):269-273.

19.    Duan Liang, Chen Xiaofeng, andJiang Gening. Lobar Torsion after Video-Assisted Thoracoscopic Lobectomy: 2Case Reports. Thoracic and Cardiovascular Surgeon,2012,60(2):167-169.

20.    Hu Xuefei, Duan Liang,Jiang Gening, Wang Hao, Liu Hongcheng, Cheng Chang. Risk Factors for EarlyPostoperative Complications After Pneumonectomy for Benign Lung Disease. AnnThorac Surg. 2013, 95:1899–1904.

21.    Hu Xuefei, Duan Liang,Jiang Gening, Wang Hao, Liu Hongcheng, Cheng Chang. A Clinical Risk Model forthe Evaluation of Bronchopleural Fistula in Non-Small Cell Lung Cancer AfterPneumonectomy. Ann Thorac Surg. 2013, 96:419–424.

22.    Duan Liang, You Qinjun, Chen Xiaofeng,Wang Hao, Zhang H, Xie Dong, Xu X, Jiang Gening. Outcome and prognosis forpatients younger than thirty with primary lung cancer. Minerva Chirurgica,2013, 68(2):1-182.

23.    徐勇，刘春燕，刘延群，李亚强，段亮，姜格宁. 激光打孔脱细胞基质复合骨髓间充质干细胞构建组织工程气管软骨.组织工程与重建外科杂, 2019, 15(2):72-76.

24.    鞠进，段亮，于戈，胡学飞，边栋亮. 胸腔镜辅助小切口胸膜剥脱术治疗青少年机化期结核性脓胸26例.中华胸心血管外科杂志, 2017,33(10):601-602.

25.    段亮，朱余明，胡学飞，边栋亮，徐勇，姜格宁. 52例单孔胸腔镜解剖性肺段切除术临床分析和技术探讨.中华胸心血管外科杂志, 2017,33(4):208-211.