本团队主要聚焦于骨肌影像学临床和基础研究，在骨质疏松影像学和关节软骨UTE-MRI成像方面耕耘15年，获得国家自然科学基金面上项目3项、青年项目2项及省部级项目10余项，发表SCI论文45篇，发明专利2项，获得上海市医学科技奖三等奖“多模态影像学新技术对骨关节退行性疾病早期诊断的创新应用，2019.5.编号2018030201”、上海市科技进步二等奖“多模态影像学对骨质疏松早期诊断关键技术的创新应用与推广，2020.12.29. 编号：20204069-2-R01”。另外，团队在乳腺癌影像、心脏MRI、肠道结构和传输MRI成像、脑fMRI方面也有建树。培养、毕业博士研究生13人，硕士研究生45人。

1.机会性QCT精准诊断骨质疏松和肌少症的临床研究。上海市科委“科技创新行动计划”医学创新研究专项项目，2020/12/01-2023/11/30，项目编号：20Y11911800，在研，30万元。

2.基于11.7T核磁共振波谱的骨髓脂肪酸代谢组学对骨质疏松发生机制的研究。国家自然科学基金面上项目，项目批准号：81871325，58万元   2019/01/01-2022/12/31

1. Kun Peng#, Xueli Zhang#, Ting Hua, Lidi Wan, Fuxia Xiao , Xianling Zhang, Yong Liu, Yali Xu,  Huan Tang,Shuai Wang, Guangyu Tang*.Evaluation of leftventricular blood flow kinetic energy in patients with hypertension by four‑dimensionalflow cardiovascular magnetic resonance imaging: a preliminary study. EuropeanRadiology, 2023,24:  https://doi.org/10.1007/s00330-023-09449-8(IF:7.034/Q1)

2. Sizhu Wang#, Cuisong Tang#,Jieying Chen, Huan Tang, Lin Zhang* and Guangyu Tang*. Changes in Bone MarrowFatty Acids Early after Ovariectomy-Induced Osteoporosis in Rats and PotentialFunctions. Metabolites, 2023, 13, 36. (IF:5.581/Q2)

3.  Sizhu Wang#, Cuisong Tang#, Jieying Chen,Huan Tang, Lin Zhang*, Guangyu Tang*. Bone marrow fatty acids affectosteoblastic differentiation through miR-92b-3p in the early stages ofpostmenopausal osteoporosis. Heliyon. 2023 May 22;9(6):e16513.

4. TangR#, Tang G#, Hua T, Tu Y, Ji R, Zhu J*. mDIXON-Quant technique diagnosticaccuracy for assessing bone mineral density in male adult population. BMCMusculoskelet Disord. 2023, 24(1):125. （IF=2.562）

5. JunZhang, Jiayi Liu, Zhipeng Liang, Liang Xia, Weixiao Zhang, Yanfen Xing, XueliZhang  and Guangyu Tang*. Differentiationof acute and chronic vertebral compressionfractures using conventional CT based on deep transfer learning features and hand-crafted radiomics features. BMCMusculoskelet Disord. 2023, 24:165（IF=2.562）

6. TuY# , Tang G# , Li L, Ji R, Tang R, Wang S, Zhu J*. A preliminary study ondegenerate characteristics of lumbar and abdominal muscles in middle-aged andelderly people with varying bone mass. BMC Musculoskelet Disord. 2023,24(1):136. （IF=2.562）

7. Xueli Zhang†, Kun Peng†, Gang Li, Lidi Wan,Tingting Xu, Zhijun Cui, Fuxia Xiao, Li Li, Zhanju Liu, Lin Zhang* and GuangyuTang*. Evaluation of bone mineral density and body compositions interrelationin young and middle-aged male patients with Crohn's disease by quantitative computedtomography. Frontiers in Endocrinology, 2022, Sep,  23（13）： 953289.  (IF:6.055/Q1)

8. Xiaolian Su# , YixuanZhang# , Qiuming Gao, Zonghui Liang, Lidi Wan, Lin Zhang*, Guangyu Tang*. Preliminarystudy on the assessment of early cartilage degeneration by quantitativeultrashort echo time magnetic resonance imaging in vivo. Quant Imaging Med Surg2022;12(7):3803-3812. https://dx.doi.org/10.21037/qims-21-1181 (IF:4.630)

9. WangliCai#, Yujing Zhou#, Lidi Wan, Ruiling Zhang, Ting Hua, Jian Gong, Bo Yang andGuangyu Tang*. Transcriptomic Signatures Associated With Gray Matter Volume Changesin Patients With Functional Constipation. Frontiers in Neuroscience,2022,15(1):05 doi: 10.3389/fnins.2021.791831 (IF:5.152)

10. Fuxia Xiao#, Lin Zhang#,Sihua Yang, Kun Peng, Ting Hua and Guangyu Tang*. Quantitative analysis of the MRI features in the differentiation of benign, borderline and malignantepithelial ovarian tumors. Journal of Ovarian Research, 2022, 15:13(IF:5.506)

11. JunjieFang, Wei Sun, Dan Wu 2 , Peipei Pang, Xiuyu Guo, Chunyao Yu, Wei Lu* andGuangyu Tang*. Value of textureanalysis based on dynamiccontrast-enhanced magnetic resonance imaging in preoperative assessment of extramural venous invasion in rectal cancer. Insights into Imaging,2022, 13:179.  IF= 5.036, https://doi.org/10.1186/s13244-022-01316-2

12.  RuiJi# , Lin Zhang#, Yongju Shen, Rui Tang, Yun Tu, Guangyu Tang * and Jingqi Zhu*. Correlation between musculoskeletalmass and perfusionin patientswith gastrointestinalmalignancy: a preliminarystudy based on quantitativeCT and CTperfusion. BMC Musculoskeletal Disorders, 2022, 23:334, https://doi.org/10.1186/s12891-022-05288-8, IF=2.335

13. Jieying Chen#, Mingchen Lv#, Xiaolian Su, Sizhu Wang, Yitong Wang, Zhen Fan, Lin Zhang*, Guangyu Tang*.ICAM1-Targeting Theranostic Nanoparticles for Magnetic Resonance Imaging andTherapy of Triple-Negative Breast Cancer. International Journal of Nanomedicine,2022:17 5605–5619(IF: 7.033/Q1)

14. Jieying Chen, Xiaolian Su,Tingting Xu , Qifeng Luo, Lin Zhang* and Guangyu Tang*. Stratification ofaxillary lymph node metastasis risk with breast magnetic resonance imaging inbreast cancer. Future Oncol.2022 Feb, doi: 10.2217/fon-2021-1559(IF:3.674)

15.  CuisongTang#, Dengpan Liang#, Yuyou Qiu, Jingqi Zhu and Guangyu Tang*. Omentin‑1 induces osteoblast viability and differentiation viathe TGF‑ β /Smad signaling pathway in osteoporosis. MolecularMedicine Reports, 2022, 25: 132.( IF=3.423)

16. HongXu, Yuyou Qiu, Zuogang Xiong, Wenjun Shao, Qi Zhang*, Guangyu Tang*. Trackingmesenchymal stem cells with Ir(III) complex-encapsulated nanospheres in craniumdefect with postmenopausal osteoporosis. Materials Science & Engineering C.2021, 122:111842(IF:7.328).

17. Jingqi Zhu, Zhangwei Yang, Rui Tang,Guangyu Tang*. Comparison of pathological, radiological, and prognosticfeatures between cellular schwannoma and non-cellular schwannoma. EuropeanJournal of Radiology, 2021, 141:109783 (IF:3.528)

18. YaoyanQiu, Tingting Sun, Feijia Xu, Peng Gao*, Guangyu Tang*, Qing Peng*. Correlationof vascular change and cognitive impairment in age-related macular degenerationpatients. Am J Transl Res 2021;13(1):336-348(IF:4.060).

19. LidiWan, Yajun Ma, Jiawei Yang, Saeed Jerban, Adam C. Searleman, Michael Carl, NicoleLe, Eric Y. Chang, Guangyu Tang*, Jiang Du. Fast quantitative three-dimensionalultrashort echo time (UTE) Cones magnetic resonance imaging of major tissues inthe knee joint using extended sprial sampling. NMR in Biomedicine. 2020Oct;33(10):e4376. (IF:3.414).

20. JiaweiYang#, Hongda Shao#, Yajun Ma, Lidi Wan, Yixuan Zhang, Junjie Jiang , Jiang Du,Guangyu Tang*. Quantitative ultrashort echo time magnetization transfer(UTE-MT) for diagnosis of early cartilage degeneration: comparison with UTE-T2*and T2 mapping. Quant Imaging Med Surg. 2020;10(1):171-183(IF:3.226)

21. ShenghuaLiu#, Feijia Xu#, Tianyuan Xu, Yang Yan, Xudong Yao*, Guangyu Tang*. Evaluationof Vesical Imaging-Reporting and Data System (VI-RADS) scoring system inpredicting muscle invasion of bladder cancer. Transl Androl Urol,2020;9(2):445-451(IF:2.445).

22. Sihua Yang, Huan Tang#, Fuxia Xiao,Jingqi Zhu, Ting Hua, Guangyu Tang*. Differentiation of borderline tumors from typeI ovarian epithelial cancers on CT and MR imaging. Abdominal Radiology. 2020Oct;45(10):3230-3238. (IF:2.429)

23.  ChuanXu, Fuan Wang, Penghua Lv, Xicheng Zhang, Guangyu Tang*. Endovascular treatmentcombined with vertebral artery endarterectomy for patients with acute tandemvertebrobasilar artery occlusion. Journal of Clinical Neuroscience,2020,79:21-29(IF=1.76)