上海市第十人民医院（简称十院）心内科为国家临床重点专科，目前已发展为一个门类齐全、医疗技术力量雄厚，集医疗、教学、科研于一体的综合性临床科室。心内科现主要有5大亚学科10大专病中心，实际开放床位180张，拥有5台DSA，IABP、OCT、IVUS、FFR、三维心超等多种大型仪器。各类介入手术量每年达9000例以上。年门诊量近40万，出院人数逾10000人次。心脏中心是国家卫健委冠心病介入及心律失常介入诊疗培训基地，急性心肌梗死信息化救治为特色。上海申康系统急性心肌梗死PCI救治手术量排行前三，左心耳封堵术为国内手术例数最多的中心之一。

      随着医疗技术的不断进步，心内科团队在心血管疾病的精准诊疗方面取得了显著成就。除了OCT、IVUS、CaFFR、FFR、IMR、QFR、Dspect等先进诊疗技术外，心内科团队还成功开展心内膜心肌活检术，通过心内膜心肌活检为诸如心肌炎、心肌病等心脏疾病的诊断提供了更为精确的病理学依据，这一技术的开展，不仅提高了我科对心脏疾病的诊断能力，也为患者提供了更为个性化和精准的治疗方案。此外，心内科新开展了心磁图检查，利用极高灵敏磁探测器，检测心脏磁场信号进行分析，精准评估冠脉微循环障碍。

      科内医师全部研究生及以上学历，博导7名，硕导18名，高级职称25名；近5年连续获得国家自然科学基金项目30余项，先后承担国家临床重点专科项目、科技部国家重点研发项目、国家自然科学基金、上海市公共卫生体系建设三年行动计划、上海市重要疾病联合攻关重大项目、科技部十二五支撑计划1、863项目子课题等，科研经费总计逾亿元。在Lancet、JACC、Circulation等知名学术期刊发表SCI论文400余篇，发布科普作品超百篇。

      在国际上首创“院前、院中、院间”三位一体的信息化心梗急救体系，打破我国区域心梗救治水平不平衡，极大提高心梗诊治效率。团队由此获得科技部重点研发项目在内的多项国家级课题支持，成果应用于包括西藏、新疆在内100余家医疗机构，在西藏建立了全球海拔最高的胸痛中心。发现新型分子标记物及血流生理精准评估心梗预后及指导个体化治疗。首创基于人工智能算法的心电预警系统及设备，获批国家医疗器械注册证，应用于国内200余家单位，为2020年珠峰测量、南极长城站科考队保驾护航。针对急性心梗起病急、预后差等问题，同济大学的教育部重点实验室及泛血管研究所的专家通过影像学、基因组学等方法发现了心梗诊治新机制及新靶点，为心梗的早期诊断及优化治疗提供了全新思路。除此之外，学科在左心耳封堵、遗传性心律失常诊治、腔内影像技术都获得国际领先地位，相关成果发表于心血管权威杂志。在中美医学同道的全力协调和努力下，同济大学附属第十人民医院心脏中心联合“美国华裔心脏协会（CNAHA）”成立全国首家“中美联合心血管专科医师培训中心”。培训内容包含定期举办中美心血管专科医师GAP-CCBC疑难病例讨论会、中美联合查房等活动。每年作为承办单位邀请来自美国、德国、新加坡及我国台湾、香港、澳门等数十位华裔专家在东方心脏病学会议-华语国际论坛进行学术交流。从国际视野角度，聚焦世界华人“心”力，在心血管医学的领域中共同探索、不断前行。

（1)国家自然科学基金委员会，面上项目，82170521，基于易损斑块多源异构特征融合的心血管不良事件风险预测模型研究，2022/01-2025/12，55万，在研，主持

（2)国家自然科学基金委员会，面上项目，81570436，Oncostatin M在肾动脉狭窄加速动脉粥样硬化中的作用及机制研究，2016/01-2019/12，68.4万，结题，主持

（3)上海申康医院发展中心，市级医院诊疗技术推广及优化管理项目，SHDC12024120，基于无创冠脉造影微血管阻力指数的冠脉微循环障碍创新临床诊断体系应用与推广，2024/06-2027/05，30万，在研，主持

（4)上海市科委，上海市医学引导项目基金，124119a6900，肾动脉狭窄加速性动脉粥样硬化相关炎性因子及其对心血管不良事件的预测价值， 10万元，2012/10-2015/10，结题，主持

（5)上海市科委，上海市自然科学基金，环状RNA circRic8b通过HuR-SIRT1轴参与心肌细胞凋亡在缺血再灌注损伤中的作用及机制研究， 21ZR1449500，20万元，2021.7～2024.6，在研，主持

（6)上海市科委，上海市自然科学基金，11ZR1428200，microRNA调控Gelsolin参与心梗后心肌重塑的机制研究，10万元，2011/3-2014/4，结题，主持

（7)上海市卫健委，面上项目，201640053，LncRNA TUG1在急性心肌梗死诊断及预后评判中的作用研究，2017/1-2019/12，10万，结题，主持

（8)西藏自治区科技厅、卫健委，自然科学基金组团式援藏医学项目，XZ2022ZR-ZY27(Z)，高原环境对冠状动脉微循环的影响及高原冠脉微循环障碍性心脏病的预后风险分析，2022/6-2024/5，14.53万，在研，主持

（9)西藏自治区科技厅、卫健委，自然科学基金重点项目，XZ202301ZR0032G，高原肺动脉高压患者肠道微生态特征及其代谢组学机制研究，2023/1-2025/12，18.8万，在研，主持

（10)西藏自治区日喀则市科技局，高原性心脏病患者肠道微生态特征及其代谢组学机制研究，2022/6-2025/5，20万，在研，主持

（11)同济大学，中央高校基本科研业务费专项资金-人工智能领域学科交叉重点项目，22120190211，基于体视化智能建模理论的多模态心血管影像定量检测与分析研究，2019/9- 2021/9，60万，在研，主持

（12)同济大学，优秀青年人才培养行动计划，2009KJ011，1501219024，心梗后心肌重塑过程中miRNA表达特征， 2009/10-2012/10，2万元，结题，主持

（13)上海市崇明区科委，“可持续发展科技创新行动计划”项目，CKY2021-21，心脏植入性电子器械术后患者合并房颤不同治疗策略的疗效与安全性评价，2021/4-2023/3，3万，在研，主持

（14)上海市崇明区科委，“可持续发展科技创新行动计划”项目，CKY2020-29，崇明区冠状动脉非阻塞性心肌梗死患者的临床特征、诊疗现状及预后分析，2020/4-2022/3，3万，在研，主持

（15)上海市崇明区科委，“可持续发展科技创新行动计划”项目，CKY2017-16，崇明心肌梗死基层胸痛中心救治模式的建立，2017/4-2019/3，3万，结题，主持

（16)上海市崇明区科委，“可持续发展科技创新行动计划”项目，CKY2018-18，崇明区早发急性心肌梗死患者家族性高胆固醇血症患病率及诊疗现状研究，2018/4-2020/3，3万，结题，主持

（17)上海市第十人民医院，350项目：IVUS/OCT/FFR优化复杂冠脉病变PCI治疗，  2017/6-2019/5，3万，结题，主持

（18)南京医科大学，教育研究项目：反转课堂模式在MBBS心脏病学教学中的运用评价，2019/1-2021/12，重点自筹，结题，主持

（19)上海市第十人民医院，2012院优秀学术骨干培养计划，12XSGG103，Oncostatin M在肾动脉狭窄加速性动脉粥样硬化中的作用及机制，10万元，2012/7-2014/6，结题，主持

（20)上海市第十人民医院，院内临床研究项目，基于caIMR诊断的微循环障碍对MINOCA患者预后评估价值的前瞻性多中心队列研究，30万元，2021/10-2024/9，在研，主持

（21)上海市第十人民医院，研究型医师A类项目，基于心内膜心肌活检组织多组学分析的冠脉微循环障碍性疾病的特征和机制研究，30万元，2023/7-2026/6，在研，主持

（22)上海市第十人民医院，院内科普培育项目，修“心”养性，远离伤“心”事——心血管病预防和康复知识的科学普及，0.3万元，2021/8-2022/7，在研，主持

（23)同济大学附属十院临床医学院，教学课题，反转课堂联合情景模拟模式在MBBS心脏病学教学中的运用评价， 2022/1-2023/12，0.8万元，在研，主持

1)     ChenL, Sang C, Wu Y, Chen W, Ren Y, Che W, Lu Y. Coronary Angiography-Derived Indexof Microcirculatory Resistance Associated With New-Onset Atrial Fibrillation inPatients With STEMI. Can J Cardiol. 2024 Mar;40(3):434-443. doi:10.1016/j.cjca.2023.10.025. Epub 2023 Nov 7. PMID: 37940088. (共通 IF:5.8, JCR:Q1)

2)     ZhangW, Liu L, Yin G, Mohammed AQ, Xiang L, Lv X, Shi T, Galip J, Wang C, MohammedAA, Mareai RM, Yu F, Abdu FA, Che W. Triglyceride-glucose index is associatedwith myocardial ischemia and poor prognosis in patients with ischemia and noobstructive coronary artery disease. Cardiovasc Diabetol. 2024 May31;23(1):187. doi: 10.1186/s12933-024-02230-1. PMID: 38822373; PMCID:PMC11140859.(共通 IF:8.5, JCR: Q1)

3)     AlifuJ, Xiang L, Zhang W, Qi P, Chen H, Liu L, Yin G, Mohammed AQ, Lv X, Shi T, AbduFA, Che W. Association between the atherogenic index of plasma and adverselong-term prognosis in patients diagnosed with chronic coronary syndrome.Cardiovasc Diabetol. 2023 Sep 21;22(1):255. doi: 10.1186/s12933-023-01989-z.PMID: 37735427; PMCID: PMC10515024. (共通 IF:9.3, JCR:Q1)

4)     MohammedAA, Zhang H, Li S, Liu L, Mareai RM, Xu Y, Abdu FA, Che W. Prognostic value ofcoronary microvascular dysfunction in patients with aortic stenosis andnonobstructed coronary arteries. J Cardiovasc Med (Hagerstown). 2023 Dec1;24(12):891-899. doi: 10.2459/JCM.0000000000001561. Epub 2023 Nov 3. PMID:37942790. (共通 IF: 3, JCR:Q2)

5)     LvX, Wang C, Liu L, Yin G, Zhang W, Abdu FA, Shi T, Zhang Q, Che W. Screening andverifying the mutations in the LDLR and APOB genes in a Chinese family withfamilial hypercholesterolemia. Lipids Health Dis. 2023 Oct 18;22(1):175. doi:10.1186/s12944-023-01935-8. PMID: 37853441; PMCID: PMC10585857. (共通 IF:4.5, JCR:Q2)

6)     ChenL, Sang C, Wu Y, Chen W, Ren Y, Che W, Lu Y. Coronary Angiography-Derived Indexof Microcirculatory Resistance Associated With New-Onset Atrial Fibrillation inPatients With STEMI. Can J Cardiol. 2023 Nov7:S0828-282X(23)01874-3. doi:10.1016/j.cjca.2023.10.025. Epub ahead of print. PMID: 37940088. (共通 IF:7.2, JCR:Q1)

7)     MohammedAQ, Abdu FA, Su Y, Liu L, Yin G, Feng Y, Zhang W, Xu Y, Xu D, Che W. PrognosticSignificance of Coronary Microvascular Dysfunction in Patients With HeartFailure With Preserved Ejection Fraction. Can J Cardiol. 2023 Apr20:S0828-282X(23)00312-4. doi: 10.1016/j.cjca.2023.04.011. Epub ahead of print.PMID: 37086837. (共通 IF:7.2, JCR:Q1)

8)     ZhangH, Caobelli F, Che W, Huang Y, Zhang Y, Fan X, Hu X, Xu C, Fei M, Zhang J, LvZ, Shi K, Yu F. The prognostic value of CZT SPECT myocardial blood flow (MBF)quantification in patients with ischemia and no obstructive coronary arterydisease (INOCA): a pilot study. Eur J Nucl Med Mol Imaging. 2023Jun;50(7):1940-1953. doi: 10.1007/s00259-023-06125-3. Epub 2023 Feb 14.PMID:36786817; PMCID: PMC10199834. (共通 IF:9.1, JCR:Q1)

9)     ZhangW, Liu L, Chen H, Li S, Wan M, Mohammed AQ, Xu B, Yin G, Lv X, Shi T, Galip J,Mohammed AA, Mareai RM, Xu Y, Abdu FA, Che W. Association between thetriglyceride-glucose index and the presence and prognosis of coronarymicrovascular dysfunction in patients with chronic coronary syndrome.Cardiovasc Diabetol. 2023 May 13;22(1):113. doi: 10.1186/s12933-023-01846-z.PMID:37179333; PMCID: PMC10183136. (共通 IF:9.3, JCR:Q1)

10)  Abdu,F.A., J. Galip, P. Qi, W. Zhang, A.Q. Mohammed, L. Liu, G. Yin, A.A. Mohammed,R.M. Mareai, R. Jiang, Y. Xu,W. Che: Association of stress hyperglycemia ratioand poor long-term prognosis in patients with myocardial infarction withnon-obstructive coronary arteries. Cardiovasc Diabetol. 2023; 22(1):11. (共通 IF:9.3, JCR:Q1)

11)  MohammedAA, Zhang H, Abdu FA, Liu L, Singh S, Lv X, Shi T, Mareai RM, Mohammed AQ, YinG, Zhang W, Xu Y, Che W. Effect of nonobstructive coronary stenosis on coronarymicrovascular dysfunction and long-term outcomes in patients with INOCA. ClinCardiol. 2022 Dec 25. doi: 10.1002/clc.23962. Epub ahead of print. PMID:36567512. (共通 IF:2.7, JCR:Q3)

12)  MareaiRM, Mohammed AQ, Zhang H, Liu L, Zhang W, Mohammed AA, Yin G, Lv X, Xu Y, AbduFA, Che W. Prognostic implication of coronary slow flow assessed by cTFC inpatients with myocardial infarction with Non-obstructive coronary arteries. EurJ Intern Med. 2022 Dec 1:S0953-6205(22)00417-4. doi:10.1016/j.ejim.2022.11.026. Epub ahead of print. PMID: 36464551. (共通 IF:8.0, JCR:Q1)

13)  ZhangW, Singh S, Liu L, Mohammed AQ, Yin G, Xu S, Lv X, Shi T, Feng C, Jiang R,Mohammed AA, Mareai RM, Xu Y, Yu X, Abdu FA, Che W. Prognostic value ofcoronary microvascular dysfunction assessed by coronary angiography-derivedindex of microcirculatory resistance in diabetic patients with chronic coronarysyndrome. Cardiovasc Diabetol. 2022 Oct 29;21(1):222. doi: 10.1186/s12933-022-01653-y.PMID: 36309724; PMCID: PMC9618191. (共通 IF:9.3, JCR:Q1)

14)  ZhangH, Che W, Shi K, Huang Y, Xu C, Fei M, Fan X, Zhang J, Hu X, Hu F, QinS, Zhang X, Huang Q, Yu F. FT4/FT3 ratio: A novel biomarker predicts coronarymicrovascular dysfunction (CMD) in euthyroid INOCA patients. Front Endocrinol(Lausanne). 2022 Sep 15;13:1021326. doi: 10.3389/fendo.2022.1021326. PMID:36187090; PMCID: PMC9520241. (共一 IF:6.055, JCR:Q1)

15)  MohammedAA, Liu L, Mareai RM, Mohammed AQ, Yin G, Singh S, Xu Y, Abdu FA, Che W.Combination of White Blood Cell Count to Mean Platelet Volume Ratio andNeutrophil-to-Platelet Ratio Predicts Long-Term Adverse Events in Patients withMINOCA. Mediators Inflamm. 2022 Aug 16;2022:5642406. doi: 10.1155/2022/5642406. PMID:36016662; PMCID: PMC9398882. (共通 IF:4.529, JCR:Q2)

16)  FengC, Abdu FA, Mohammed AQ, Zhang W, Liu L, Yin G, Feng Y, Mohammed AA, Mareai RM,Lv X, Shi T, Xu Y, Yu X, Che W. Prognostic impact of coronarymicrovascular dysfunction assessed by caIMR in overweight with chronic coronarysyndrome patients. Front Endocrinol (Lausanne). 2022 Aug 10;13:922264. doi:10.3389/fendo.2022.922264. PMID: 36034462; PMCID: PMC9399838. (共通 IF:6.055, JCR:Q1)

17)  LiuL, Dai N, Yin G, Zhang W, Mohammed AQ, Xu S, Lv X, Shi T, Feng C,Mohammed AA,Mareai RM, Xu Y, Yu X, Abdu FA, Yu F, Che W. Prognostic value ofcombined coronary angiography-derived IMR and myocardial perfusion imaging byCZT SPECT in INOCA. J Nucl Cardiol. 2022 Aug 2. doi:10.1007/s12350-022-03038-w. Epub ahead of print. PMID: 35918592 (共通 IF:3.872, JCR:Q2)

18)  WangC, Wu Y, Su Y, Mao B, Luo Y, Yan Y, Hu K, Lu Y, Che W, Wan M. Elevatedlevels of sIL-2R, TNF-α and hs-CRP are independent risk factors for postpercutaneous coronary intervention coronary slow flow in patients with non-STsegment elevation acute coronary syndrome. Int J Cardiovasc Imaging. 2022 Feb19. doi: 10.1007/s10554-022-02529-8. Epub ahead of print. PMID: 35182256. (共通 IF:2.316, JCR:Q3)

19)  YinG, Liu L, Mohammed AQ, Jiang R, Abdu FA, Che W. Association between InitialSerum Total Bilirubin and Clinical Outcome in Myocardial Infarction withNon-Obstructive Coronary Arteries. Int J Med Sci. 2022 May 27;19(6):986-992.doi: 10.7150/ijms.70833. PMID: 35813292; PMCID: PMC9254374. (共通 IF:3.642, JCR:Q2)

20)  ZhangH, Shi K, Fei M, Fan X, Liu L, Xu C, Qin S, Zhang J, Wang J, Zhang Y, Lv Z,Che W, Yu F. A Left Ventricular Mechanical Dyssynchrony-Based Nomogram forPredicting Major Adverse Cardiac Events Risk in Patients With Ischemia and NoObstructive Coronary Artery Disease. Front Cardiovasc Med. 2022 Mar18;9:827231. doi: 10.3389/fcvm.2022.827231. PMID: 35369339; PMCID: PMC8971375.(共通 IF:6.050, JCR:Q1)

21)  AbduFA, Mohammed AQ, Liu L, Yin G, Xu S, Mohammed AA, MareaiRM, Xu YW, Che WL. Metabolic syndrome and the risk of adverse cardiovascularevents in patients with myocardial infarction with non-obstructive coronaryarteries. Nutrition, Metabolism and Cardiovascular Diseases. 2022, DOI:https://doi.org/10.1016/j.numecd.2022.01.007.(通讯, IF:4.666, JCR:Q2)

22)  XuS, Liu L, Yin G, Mohammed AQ, Lv X, Feng C, Shi T, Che W. PrognosticSignificance of Uric Acid in Patients with Obstructive and NonobstructiveCoronary Artery Disease Undergoing D-SPECT. Clin Interv Aging. 2021 Nov16;16:1955-1965. doi: 10.2147/CIA.S339600. PMID: 34815667; PMCID: PMC8605808. (通讯, IF:4.458, JCR:Q2)

23)  MohammedAQ, Abdu FA, Liu L, Zhang W, Yin G, Xu Y, Che W. Hyperuricemia Predicts AdverseOutcomes After Myocardial Infarction With Non-obstructive Coronary Arteries.Front Med (Lausanne). 2021 Sep 9;8:716840. doi: 10.3389/fmed.2021.716840.eCollection 2021. (通讯, IF:5.091, JCR:Q1) 报销

24)  DaiN, Che W, Liu L, Zhang W, Yin G, Xu B, Xu Y, Duan S, Yu H, Li C, Yao K, HuangD, Ge J.*Diagnostic Value of Angiography-Derived IMR for CoronaryMicrocirculation and Its Prognostic Implication After PCI. Front CardiovascMed. 2021 Oct 15;8:735743. doi: 10.3389/fcvm.2021.735743. eCollection 2021. (共一, IF:6.050, JCR:Q1)

25)  AbduFA, Mohammed AQ, Liu L, Zhang W, Yin G, Xu B, Xu S, Xu Y, Che WL*. Low FreeTriiodothyronine as a Predictor of Poor Prognosis in Patients With MyocardialInfarction With Non-Obstructive Coronary Arteries. Frontiers in endocrinology.2021 May; 12: p681978. (通讯, IF5.555, JCR:Q1)

26)   Abdu FA, Liu L, Mohammed AQ, YinG, Xu B, Zhang W, Xu S, Lv X, Fan R, Feng C, Shi T, Huo Y, Xu Y, Che WL*.Prognostic impact of coronary microvascular dysfunction in patients withmyocardial infarction with non-obstructive coronary arteries. European journalof internal medicine. 2021 Oct;92:79-85.doi: 10.1016/j.ejim.2021.05.027. (通讯, IF:4.624, JCR:Q1)

27)  YinG, Abdu FA, Liu L, Xu S, Xu B, Luo Y, Lv X, Fan R, Che WL*. Prognostic Value ofGRACE Risk Scores in Patients With Non-ST-Elevation Myocardial Infarction WithNon-obstructive Coronary Arteries. Frontiers in cardiovascular medicine. 2021 Feb; 8: p582246. (通讯, IF: 6.050, JCR:Q1) 报销

28)  MohammedAQ, Abdu FA, Liu L, Xu B, Xu S, Yin G, Feng C, Lv X, Fan R, Che WL*, Xu Y. DoesSex Influence Outcomes in Myocardial Infarction With non-obstructive CoronaryArteries (MINOCA)? Angiology. 2021 Jun. (通讯, IF:3.619, JCR: Q2)

29)  XuB, Liu L, Abdu FA, Yin G, Mohammed AQ, Xu S, Lv X, Fan R, Cai F, Shi T, ZhangW, Xu Y, Cai H, Yu F, Che WL*. Prognostic value of diastolic dysfunctionderived from D-SPECT in coronary artery disease patients with normal ejectionfraction. Front Cardiovasc Med. 2021 Jun. (通讯，IF:6.050, JCR:Q1)

30)  ZhangBC, Wang WN, Xiao YT, Xiao SX, Chen SC, Chen SR, Xu GW, Che WL*. Cross-Subject SeizureDetection in EEGs Using Deep Transfer Learning. Comput Math Methods Med. 2020 May8;2020:7902072. doi: 10.1155/2020/7902072. (通讯，IF:2.238, JCR:Q3)

31)  AbduFA, Liu L, Mohammed AQ, Xu B, Yin G, Xu S, Xu Y, Che WL*. Effect of Secondary Prevention Medication on thePrognosis in Patients With Myocardial Infarction With Nonobstructive CoronaryArtery Disease. J Cardiovasc Pharmacol. 2020 Dec;76(6):678-683. (通讯，IF:3.105, JCR:Q2)

32)  XuB, Abdu FA, Liu L, Mohammed AQ, Yin G, Luo Y, Xu S, Lv X, Fan R, Che WL*. Clinical Outcomes andPredictors of ST-Elevation Versus Non-ST-Elevation Myocardial Infarction withNon-Obstructive Coronary Arteries. Am J Med Sci. 2020 Dec;360(6):686-692. (通讯，IF:2.378, JCR:Q3)

33)  ZhangGK, Luo JH, Han LT, Lu ZY, Hua R, Chen JQ,Che WL*. A Dynamic Multi-scale Network For EEG SignalClassification. Frontiers in Neuroscience. 2021 Jan 13;14:578255. doi:10.3389/fnins.2020.578255. (通讯，IF:4.677, JCR:Q2）

34)  ZhangG, Yang L, Li B, Lu Y, Liu Q, Zhao W, Ren T, Zhou J, Wang SH, Che W.MNL-Network: A Multi-Scale Non-local Network for Epilepsy Detection From EEGSignals. Front Neurosci. 2020 Nov 17;14:870. doi: 10.3389/fnins.2020.00870.PMID: 33281538; PMCID: PMC7705239.

35)  ZhangYQ, Chen JL,Tan JH, Chen YX, Chen YY, Li DH, Yang L, Su J, Huang X, Che WL*. An Investigation ofDeep Learning Models for EEG-based Emotion Recognition. Front Neurosci. 2020Dec 23;14:622759. doi: 10.3389/fnins.2020.622759. (通讯，IF:4.677, JCR:Q2)

36)  XuG, Ren T, Chen Y, Che W. A One-Dimensional CNN-LSTM Model for Epileptic SeizureRecognition Using EEG Signal Analysis. Front Neurosci. 2020 Dec 10;14:578126.doi: 10.3389/fnins.2020.578126. PMID: 33390878; PMCID: PMC7772824.

37)  Zhang GK, Yang L, Li BY, Lu YW, Liu QY, Zhao W, RenTH, Zhou JS, Wang SH, Che WL*. A new Pulse Coupled Neural Network (PCNN) for Brain Medical Image Fusionempowered by Shuffled Frog Leaping. Front. Neurosci. 2020 Nov 17;14:870. doi:10.3389/fnins.2020.00870. (通讯，IF:4.677, JCR:Q2)

38)   Liu L, Abdu FA, Yin G, Xu B,Mohammed AQ, Xu S, Lv X, Luo Y, Zu L, Yang C, Zhang Z, Zhou X, Cai H, Lv Z, XuY, Che WL*. Prognostic valueof myocardial perfusion imaging with D-SPECT camera in patients with ischemiaand no obstructive coronary artery disease (INOCA). J Nucl Cardiol. 2020 Sep 30. doi:10.1007/s12350-020-02252-8. (通讯，IF:5.952，JCR:Q1)

39)  AbduFA, Liu L, Mohammed AQ, Luo Y, Xu S, Auckle R, Xu Y, Che WL*. Myocardial infarction withnon-obstructive coronary arteries (MINOCA) in Chinese patients:Clinicalfeatures, treatment and 1 year follow-up. Int J Cardiol. 2019 Jul 15;287:27-31. (通讯，IF:4.164, JCR:Q2)

40)  Xu GW, Shen XA, Chen SR, ZongYS, Zhang CY, Yue HY, Liu M, Chen F,Che WL*. A Deep Transfer Convolutional Neural Network Framework for EEGSignal Classification. IEEE Access. 2019; 7(1):112767-112776.(通讯，IF:3.367, JCR:Q2)

41)  Huang CX, Lan YS, Chen SR, Liu Q, Luo X, Xu GW, Zhou W, LinF, Peng YH, Ng Eddie Y. K.; Cheng YQ, Zeng NY*, Zhang GK*, Che WL*. Patient-Specific Coronary Artery 3D Printing Basedon Intravascular Optical Coherence Tomography and Coronary Angiography.COMPLEXITY, 2019, 2019: 5712594. (通讯，IF:2.833, JCR:Q2)

42)  Xu GW, Lan YS, Zhou W, Huang CX*, Li WB, Zhang W, Zhang GK,Ng E. Y. K.; Cheng YQ, Peng YH*, CheWL*. An IoT-Based Framework of Webvr Visualization for Medical Big Datain Connected Health. IEEE ACCESS, 2019 冬季, 7: 173866-173874. (通讯，IF:3.367, JCR:Q2)

43)  Tang JJ, Lan YS, Chen SR, Zhong YS, Huang CX, Peng YH,Liu QY*, Cheng YQ*, Chen F*, Che WL*.Lumen Contour Segmentation in IVOCT Based on N-type CNN. IEEE Access, 2019, 7:135573-135581. (通讯, IF:3.367, JCR:Q2)

44)  LanYS, Zhou YH, Lu YW, Wang H, Liu Q, NG E.Y.K., Peng YH, Hao YT, Liu QY, Chen F,Cheng Y, Che WL*. A NineMonths Follow-up Study of Hemodynamic Effect on Bioabsorbable Coronary StentImplantation. IEEEAccess. 2019; 7(1): 112564-112571. (通讯，IF:3.367, JCR:Q2)

45)  LanYS, Ding YM, Luo X, Zhang YZ, Huang CX, Huang WH, Zhou XZ, Su J, Peng YQ, WangZC, Cheng YQ, Che WL*. A Clustering based TransferFunction for Volume Rendering Using Gray-Gradient Mode Histogram. IEEE Access. 2019;7:80737-80747.(通讯，IF:3.367, JCR:Q2)

46)  LiuL, Zhao D, Zhang J, Yang H, Abdu FA, Guo R, Li S, Tang K, Li H, Che W*, Xu Y. Impact of Stable CoronaryArtery Disease on the Efficacy of Cryoballoon Ablation for the AtrialFibrillation. Am J Med Sci. 2019 Sep;358(3):204-211. (通讯，IF:2.378, JCR:Q3)

47)  JiangS, Guo C, Zhang W, Che W*, Zhang J, Zhuang S, Wang Y, ZhangY, Liu B. The Integrative Regulatory Network of circRNA, microRNA, and mRNA inAtrial Fibrillation. Front Genet. 2019 Jun 13;10:526. doi:10.3389/fgene.2019.00526. (共同第一，IF:4.599, JCR:Q2)

48)  HuangC, Tian G, Lan Y, Peng Y, Ng EYK, Hao Y, Cheng Y, Che WL*.A New Pulse Coupled Neural Network (PCNN) for Brain Medical Image FusionEmpowered by Shuffled Frog Leaping Algorithm. Front Neurosci. 2019 Mar20;13:210. doi: 10.3389/fnins.2019.00210. (通讯，IF:4.677, JCR:Q2)

49)  MohammedAQ, Auckle R, Li HL, Xu SL, Liu L, Zhao DD, Che WL*. Pegylated Interferon-α Plus Ribavirin TherapyImproves Left Ventricular Diastolic Dysfunction in Patients With ChronicHepatitis C Attaining Sustained Virological Response. Am J Med Sci.2018;355(6):566-572. (通讯，IF:2.378, JCR:Q3)

50)  AuckleR, Su B, Li H, Xu S, Xie M, Song Y, Abdul Quddus M, Xu Y, Liu B, Che WL*. Familialhypercholesterolemia in Chinese patients with premature ST-segment-elevationmyocardial infarction: Prevalence, lipid management and 1-year follow-up. PLoSOne. 2017;12(10):e0186815. (通讯，IF: 3.240, JCR:Q2)

51)  AuckleR,  Xu SL,  Li HL, Mohammed AQ, Xie M, Su B, Liu B, Che WL*. Association ofmatrix-metalloproteinase-9 with left ventricular diastolic dysfunction inpatients with hepatitis C virus infection. Int J Clin Exp Med. 2018; 11(2):989-995. (通讯，IF: 0.166, JCR:Q4)

52)  HuangC, Shan X, Lan Y, Liu L, Cai H, CheWL*, Hao Y, Cheng Y, Peng Y*. A Hybrid Active Contour SegmentationMethod for Myocardial D-SPECT Images. IEEE Access. 2018; 6(1): 39334-39343. (共同通讯，IF:3.367, JCR:Q2)

53)  Che WL, Liu WL, Wei YD, Xu YW, Hou L,Matsumori A, Hu DY*. Increased serum N-terminal pro-B-type natriuretic peptideand left ventricle diastolic dysfunction in patients with hepatitis C virusinfection. Journal of Viral Hepatitis. 2012; 19(5): 327-331. (第一，IF: 3.728, JCR:Q3)

54)  Che WL, Zhang BC, Liu WL, Wei YD, XuYW*, Hu DY*. Association between high-sensitivity C-reactive protein andN-terminal pro-B-type natriuretic peptide in Patients with Hepatitis C VirusInfection. Mediators of Inflammation.2012;2012:730923. doi: 10.1155/2012/730923. (第一，IF: 4.711, JCR:Q2)

55)  Che WL*, Liu B, Nie F, Wei Y, Li W, ChenW, Xu Y*. Associationof TNF-α with leftventricular diastolic dysfunction in patients with hepatitisC virus infection. Int J Cardiol. 2013;168(3):2903-2904.. (第一，IF:4.164, JCR:Q2)

56)  LiuB, Che WL(co-first author),Xue JS, Zheng CZ, Tang K, Zhang JY, Wen J, Xu YW*. SIRT4 Prevents Hypoxia-InducedApoptosis in H9c2. Cardiomyoblast Cells. Cellular Physiology and Biochemistry.2013;32(3):655-662. (共一，IF:5.500, JCR: n/a)

57)  LiuB, Che WL(co-first author),Yan HW, Zhu WD, Wang HB*.Effects of Rosuvastatin vs. Simvastatin/ ezetimibe on Arterial Wall Stiffnessin Patients with Coronary Artery Disease. Internal medicine. 2013;52(24):2715-2719. (共一，IF: 1.271, JCR:Q3)

58)  LiuB, Che WL(co-first author),Zheng C, et al. SIRT5: a safeguard against oxidative stress-induced apoptosisin cardiomyocytes. Cell Physiol Biochem. 2013;32(4):1050-1059. (共一，IF: 5.500, JCR: n/a)

3. 专著

（1) 《OCT临床应用进展》第16章，科学技术文献出版社，0.25万字，2016年,ISBN:978-7-5189-1760-0

（2) 《默克家庭医学手册》第265-273节，人民卫生出版社，7.9万字，2014年

（3) 《室性心律失常与心脏性猝死》第11-16章，人民卫生出版社，3.4万字，2010年, ISBN9787117132107

（4) 《抗心律失常药物临床指南》第9-13章，人民卫生出版，1.9万字，2009年, 9787117113991

（5) 《心脏性猝死临床实践手册》第17-18章，人民卫生出版社，1.3万字，2007年, 9787117091329

（6) 《基因工程小鼠》第10章，上海科学技术出版社，3万字，2006年