1. 1         国家自然科学基金面上项目 “坏死性细胞凋亡关键蛋白RIPK3新型泛素化修饰的调控机制及在坏死性炎症中的作用研究”(No.
2.             32170748,2022.1--2025.12)
3. 2         国家自然科学基金面上项目“MLKL介导的程序性细胞坏死对乳腺癌转移的作用和分子机制研究”(No.81773075, 2018.1-
4.             -2021.12)
5. 3         宁夏回族自治区东西部合作重点研发计划“靶向坏死性凋亡和铁死亡的双功能抑制剂在缺血性脑损伤中的保护作用和机制研究”
6.             (No.2022ZDYF1083,2022.1—2024.12)
7. 4         上海市科委国际合作项目“来自泰国海洋的抗坏死性凋亡活性天然产物的发现、靶点鉴定和在坏死性炎症中的作用研究”
8.              (No.21490714300,2021.7—2024.6)
9. 5         上海市科委国际合作项目“程序性细胞坏死在肝癌肿瘤发生发展中的作用和分子机制研究” (No. 18410720600, 2018.10—2021.9)
10. 6         国家青年海外高层次人才引进计划  2017年

1       Rui C,Shi SN, Ren W, Qin X, Zhuang C, Chen X, Chen G, Yu J, Wang HY, Cai Z. Themultitargeted kinase inhibitor KW-2449 ameliorates cisplatin-inducednephrotoxicity by targeting RIPK1-mediated necroptosis. BiochemPharmacol. 2021，188:114542.

2       Qin X†,Hu L†, Shi SN†, Chen X, Zhuang C, Zhang W, Jitkaew S,Pang X, Yu J, Tan YX#, Wang HY#, Cai Z#. The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and amelioratesacute kidney injury by targeting RIPK1 and RIPK3 kinases. BiochemPharmacol. 2020,177:113947.

3       Qin X,Ma D, Tan Y#, Wang H#, Cai Z#. The role of necroptosis in cancer: a double-edgedsword? Biochim Biophys Acta Rev Cancer, 2019,1871:259-266. (#, Correspondence author) (Review)

4       Chen X†,Zhuang C†,#,Ren Y†, Zhang H, Qin X, Hu L, Fu J, Miao Z, Chai Y, Liu Z, Cai Z#,Wang H# , Identification of TAK-632 and its analogues as potent inhibitors ofnecroptosis by targeting RIPK1 and RIPK3, 2019, Br J Pharmacol,176(12):2095-2108. (#, Correspondence author; †, equal contribution)

5       Cai Z,Zhang A, Choksi S, Li W, Li T, Zhang X, and Liu Z. Activation of cell surfaceproteases promotes necroptosis, inflammation and cell migration. CellResearch, 2016, 26(8):886-900.

6       Cai Z†,Jitkaew S†, Zhao J†, Chiang H, Choksi S, LiuJ, Ward E, Wu L, Liu Z. Plasma membrane translocationof trimerized MLKL protein is required for TNF-induced necroptosis. NatCell Biol. 2014; 16(1):55-65. (†, equal contribution) (ESI Highly Cited Paper)

7       Zhao J†, Jitkaew S†, Cai Z†, Choksi S, Li Q, Luo J, Liu ZG. Mixed lineage kinasedomain-like is a key receptor interacting protein 3 downstream component ofTNF-induced necrosis. Proc Natl Acad Sci U S A. 2012;109(14):5322-7. (†, equal contribution) (ESIHighly Cited Paper)