1．国家自然科学基金杰出青年项目，DNA损伤应答与肿瘤发生发展

2．国家自然科学基金重大项目，真核细胞维持DNA复制叉稳定的机制研究

3．国家自然科学基金面上项目，FAK-OTUD4-POLQ信号轴调控微同源介导末端连接修复（MMEJ）及肿瘤耐药的分子机制研究

4．国家自然基金委优秀青年项目，DNA损伤与肿瘤发生

5．国家自然基金委衰老重大项目培育项目，去泛素化修饰SIRT7调控血管内皮衰老分子机制研究

6．国家自然科学基金面上项目，DBC1调节SIRT功能的机制研究及其在肝癌发生的作用

7．国家自然科学基金青年项目，G3BP1 在乳腺癌发生中的作用和机制研究

8．科技部 973项目，环境应激致血管内皮细胞衰老、损伤及修复的分子机制 

9．教育部新世纪人才计划，结肠癌相关分子标记物的功能研究

10. 上海市科委浦江人才计划，DBC1与SIRT1协同调控肿瘤发生的分子机制研究

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7.    KimW#,Zhao F#,Wu R, Qin S, Nowsheen S, Huang J, Zhou Q, Chen Y, Deng M, Guo G, Luo K, Lou Z*,Yuan J*. ZFP161 regulates replication fork stability and maintenance ofgenomic stability by recruiting the ATR/ATRIP complex. Nat Commun. 2019Nov 22;10(1):5304. doi: 10.1038/s41467-019-13321-z.

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9.    ChenmingWu, Kuntian Luo, Fei Zhao, Ping Yin, Ying Song, Min Deng, Jinzhou Huang, YupingChen, Lei Li, SeungBaek Lee, JungJin Kim, Qin Zhou, Xinyi Tu, Somaira Nowsheen,Qifeng Luo, Xiumei Gao,  Zhenkun Lou*,Zhongmin Liu*, Jian Yuan*.USP20 positively regulates tumorigenesis and chemoresistance through β-cateninstabilization. CellDeath&Differentiation 2018 Nov;25(10):1855-1869.

10.   Li L#, Liu T#, Li Y, Wu C, Luo K, Yin Y, Chen Y, NowsheenS, Wu J, Lou Z*, Yuan J*.The deubiquitinase USP9X promotes tumor cell survival and conferschemoresistance through YAP1 stabilization. Oncogene. 2018 May;37(18):2422-2431.

11.   LiY, Luo K, Yin Y, Wu C, Deng M, Li L, Chen Y, Nowsheen S, Lou Z, Yuan J*. USP13 regulates theRAP80-BRCA1 complex dependent DNA damage response. NatCommun. 2017 Jun 1;8: 15752.

12.   LuoK, Li Y, Yin Y, Li L, Wu C, Chen Y, Nowsheen S, Hu Q, Zhang L, Lou Z, Yuan J*.USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKTsignaling. EMBO J 2017 May15; 36 (10):1434-1446

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25.   Yuan J, Pu M, Zhang Z, Lou Z. Histone H3-K56 acetylation is importantfor genomic stability in mammals. CellCycle 2009 Jun 01; 8 (11):1747-53

26.   Yuan J, Minter-Dykhouse K, Lou Z. A c-Myc-SIRT1 feedback loop regulatescell growth and transformation. JCell Biol 2009 Apr 20; 185 (2):203-11

27.   Chen X, Gu X, Shan Y, Tang W, Yuan J, Zhong Z, Wang Y,Huang W, Wan B, Yu L. Identification of a novel human lactate dehydrogenasegene LDHAL6A, which activates transcriptional activities of AP1(PMA). Mol Biol Rep 2009 Apr; 36(4):669-76

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29.   Guo Z, Yuan J, Tang W, Chen X, Gu X, Luo K, Wang Y, Wan B,Yu L. Cloning and characterization of the human gene RAP2C, a novel member ofRas family, which activates transcriptional activities of SRE. Mol Biol Rep 2007 Sep; 34(3):137-44

30.   Tang W, Yuan J, Chen X, Gu X, Luo K, Li J, Wan B, Wang Y,Yu L. Identification of a novel human lysophosphatidic acid acyltransferase,LPAAT-theta, which activates mTOR pathway. JBiochem Mol Biol 2006 Sep 30; 39 (5):626-35

31.   Guo Z, Tang W, Yuan J, Chen X, Wan B, Gu X, Luo K, Wang Y,Yu L. BRSK2 is activated by cyclic AMPdependent protein kinase A throughphosphorylation at Thr260. BiochemBiophys Res Commun 2006 Sep 8; 347 (4):867-71

32.   Yuan J, Tang W, Luo K, Chen X, Gu X, Wan B, Yu L. Cloning andcharacterization of the human gene DERP6, which activates transcriptionalactivities of p53. Mol Biol Rep2006 Sep; 33 (3):151-8

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35.   Yuan J, Shan Y, Chen X, Tang W, Luo K, Ni J, Wan B, Yu L. Identificationand characterization of RHEBL1, a novel member of Ras family, which activatestranscriptional activities of NF-kappa B.Mol Biol Rep 2005 Dec; 32 (4):205-14

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37.   Zhang Y, Ni J, Zhou G, Yuan J, Ren W, Shan Y, Tang W, Yu L,Zhao S. Cloning, expression and characterization of the human NOB1 gene. Mol Biol Rep 2005 Sep; 32(3):185-9

38.   Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L.Characterization of a human regulatory subunit of protein phosphatase 3 gene(PPP3RL) expressed specifically in testis. MolBiol Rep 2005 Mar; 32 (1):41-5

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