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程国锋,博士,同济大学特聘教授,同济大学传染病与疫苗研究所负责人,同济大学附属第十人民医院双聘教授,同济大学脑与脊髓研究中心冠名研究员。入选国家“万人计划”科技创新领军人才、科技部中青年科技创新领军人才、中国农科英才、上海浦江人才等培养计划。曾任全国动物卫生标准化技术委员会委员、国家农业创新团队首席科学家、国家动物血吸虫病参考实验室主任和农业部动物寄生虫学重点实验副主任等。兼任F1000 member、中国细胞外囊泡学会常务委员、中国动物学会寄生虫学分会常务委员、教育部学位与研究生教育发展中心评审专家等。主持科技部国家重点研发计划重点国际合作专项,国家自然科学基金国际合作,国家自然科学基金面上项目(3项)等省部级以上科研项目18项。
目前,以第一作者或通讯作者在Nature Communications, Advanced Science, Advanced Drug Delivery Reviews, PLoS Pathogens, Journal of Biological Chemistry等国内外期刊发表论文近 100 余篇,其中4篇论文为 ESI 高被引或获F1000 推荐,参编英文专著3部,多次在本领域国际顶级学术会议进行大会(特邀)报告。研究成果获上海市自然科学奖二等奖、上海市科技进步奖二等奖、上海明治生命科学奖等。
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支持扩展名:.rar .zip .doc .docx .pdf .jpg .png .jpeg2023 年获上海市自然科学奖二等奖;
2018 年获上海市统一战线(工作)先进个人;
2017 年获国家“万人计划”科技创新领军人才;
2017 年获中国农业科学院农科英才特殊支持计划;
2016 年获科技部创新人才推进计划“中青年科技创新领军人才”;
2013 年获中国农业科学院杰出青年称号;
2010 年获上海市浦江人才称号并获资助;
2009 年获上海市人才发展资金资助;
2009 年获上海闵行领军人才;
2008 年获上海市科技进步奖二等奖
在国内外期刊发表论文100余篇,仅列出最近论文(*通讯作者)
1. Giri BR*, Cheng G*. A review on circular RNAs in helminth parasites: Insights and potential
applications. Int J Biol Macromol. 2025 Dec;333(Pt 2):148956. (IF=8.7)
2. Lan Z, Wang X, et al, Cheng G*, Wang C*. Transcriptomic profiling of Kupffer cells exposed
to Clonorchis sinensis extracellular vesicles: Unraveling the role of CSF3 in hepatic fibrosis. Food Waterborne Parasitol. 2025 Nov 21;41:e00304. (IF=3.8)
3. Shan T, Lu Z, Xia T, Wang X, Liu L, Fang C, Li S, Zheng Y, Cheng G*. Non parasite genome
encoded viruslike RNAs reprogram the pathogenicity of human blood flukes. Nat Commun. 2025 Dec 26;17(1):2995. (IF=17.2)
4. Fang C, Giri BR, Cheng G*. Quantitative proteomics and phosphoproteomics analyses
identify sexbiased protein ontologies of S. japonicum. Genomics, Proteomics & Bioinformatics PMID: 41392304 DOI: 10.1093/gpbjnl/qzaf126. (IF=9.1)
5. Wang X, Fang C, Cheng G*. Genomewide identification and functional characterization of
GPCR family genes reveal their key roles in the vitellarium development and egg production in Schistosoma japonicum. Parasit Vectors. 2025 Jul 17;18(1):286.
6. Ge Y, Liu H, Ren N, Qadeer A, Tabios IKB, Fontanilla IKC, Leonardo LR, Sripa B, Cheng G*. The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis. Pathogens. 2025 May 27;14(6):534.
7. Du P, Xia T, Li X, Giri BR, Fang C, Li S, Yan S, Cheng G*. Schistosoma sex-biased microRNAs regulate ovarian development and egg production by targeting Wnt signaling pathway. Commun Biol. 2024 Dec 31;7(1):1717. (IF=5.8)
8. Qadeer A, Cheng G*. Current understanding of immune-like responses in worms. Comparative Immunology Reports. 2025, 8: 200194
9. Lishai EA, Zaparina OG, Kapushchak YK, Sripa B, Hong SJ, Cheng G, Pakharukova MY. Comparative liver transcriptome analysis in hamsters infected with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis. PLoS Negl Trop Dis. 2024 Dec 9;18(12):e0012685. (IF=3.8)
10. Wang X, Zeng M, Cheng G*. Immunoproteomic and Immunoinformatic Approaches Identify Sensitive Antigens for Diagnosing Anisakis pegreffii Infection. ACS Infect Dis. 2024 Dec 13;10(12):4360-4368. (IF=4.2)
11. Zheng Y, Fang C, Du P, Giri BR, Wu H, Ge Y, Liu L, Wang X, Cheng G*. Molecular characterization of miR-31 for regulating egg production in female Schistosoma japonicum. Acta Trop. 2024 Nov;259:107372.
12. Wu H, Giri BR, Li H, Zheng Y, Yan X, Cheng G*. Schistosoma japonicum extracellular vesicle proteins serve as effective biomarkers for diagnosing parasite infection. Front Cell Infect Microbiol. 2024 May 16;14:1391168.
13. Wang X, Giri BR, Cui Z, Munkhjargal T, Wang C, Fontanilla IKC, Cheng G*. Development of a Gaussia luciferase immunoprecipitation assay for detecting Schistosoma japonicum infection. Exp Parasitol. 2024 Jul;262:108776.
14. Giri BR, Li S, Cheng G*. Exogenous modification of EL4 T cell extracellular vesicles with miR-155 induce macrophage into M1 type polarization. Drug Deliv Transl Res. 2024 Apr;14(4):934-944. (IF=6.2)
15. Rivera J, Mu Y, Gordon CA, Jones MK, Cheng G, Cai P. Current and upcoming point-of-care diagnostics for schistosomiasis. Trends Parasitol. 2024 Jan;40(1):60-74. (IF=8.5)
16. Liu J, Wang X, et l, Xia T, Li X, Cheng G*. Metagenomic sequencing for identifying
pathogenspecific circulating DNAs and development of diagnostic methods for schistosomiasis. iScience. 2023 Jul 27;26(9):107495. (IF=6.1)
17. Zhang M, Huang Y, et al, Yao Y, Cheng G*, Yang Y*. Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Adv Sci (Weinh). 2023:e2302250. (IF=15.6)
18. Giri BR, Cheng G*. Editorial: Roles of non-coding RNAs in infectious diseases.
Front Cell Infect Microbiol. 2023;13:1202616.
19.Giri BR, Li S, Fang C, Qiu L, Yan S, Pakharukova MY, Cheng G*. Dynamic miRNA profile of host T cells during early hepatic stages of Schistosoma japonicum infection. Front Immunol.
2022;13:911139.(IF=8.0)
20. Giri BR, Fang C, Cheng G*. Genome wide identification of circular RNAs in adult
Schistosoma japonicum. Int J Parasitol. 2022;52(9):629-636.
21.Li S, Giri BR, Liu J, He X, Cai P, Jing Z, Cheng G*. Characterization of MicroRNA Cargo of Extracellular Vesicles Isolated From the Plasma of Schistosoma japonicum-Infected Mice. Front Cell Infect Microbiol. 2022;12:803242.
22.Zaparina OG, Rakhmetova AS, Kolosova NG, Cheng G, Mordvinov VA, Pakharukova MY. Antioxidants resveratrol and SkQ1 attenuate praziquantel adverse effects on the liver in Opisthorchis felineus infected hamsters. Acta Trop. 2021:105954.
23. Qadeer A, Giri BR, Ullah H, Cheng G*. Transcriptional profiles of genes potentially involved in extracellular vesicle biogenesis in Schistosoma japonicum. Acta Trop. 2021;217:105851.
24. Xia T, Giri BR, Liu J, Du P, Li X, Li X, Li S, Cheng G*. RNA sequencing analysis of altered expression of long noncoding RNAs associated with Schistosoma japonicum infection in the murine liver and spleen. Parasit Vectors. 2020 ;13(1):601.
25. Du P, Giri BR, Liu J, Xia T, Grevelding CG, Cheng G*. Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum.
PLoS Negl Trop Dis. 2020;14(9):e0008618.
26.Liu J, Li H, Xia T, Du P, Giri B, Li X, Li X, Cheng G*. Identification of Schistosoma japonicum GSK3beta interacting partners by yeast two-hybrid screening and its role in parasite survival. Parasitol Res. 2020;119(7):2217-2226.
27.Chen Y, Giri BR, Li X, He X, Jing Z, Cheng G*. Preliminary evaluation of the diagnostic potential of Schistosoma japonicum extracellular vesicle proteins for Schistosomiasis japonica. Acta Trop. 2020;201:105184.
28. Giri BR, Cheng G*. Host miR-148 regulates a macrophage-mediated immune response during Schistosoma japonicum infection. Int J Parasitol. 2019;49(13-14):993-997.
29.Liu J, Zhu L, Wang J, Qiu L, Chen Y, Davis RE, Cheng G*. Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism. PLoS Pathog. 2019. doi.org/10.1371/journal.ppat.1007817. (IF=6.463)
30.Giri BR, Mahato RI, Cheng G*. Roles of microRNAs in T cell immunity: Implications for strategy development against infectious diseases. Med Res Rev. 2019;39(2):706-732. (IF=13.8)
1) 2025,11/27-28, 报告题目《Schistosomiasis:understanding basics toaccelerate disease elimination》, NTDASIA2025, KHON KAEN, THAILAND (特邀大会报告)
2) 2025,10/24-26, 2025第9届细胞外囊泡大会EV与免疫及感染性疾病论坛(论坛主席)
3) 2024,11/15-17, 报告题目《HelminthExtracellular Vesicles: UnderstandingRegulatory Roles and their Applicationsfor Diagnosis and Vaccine Development》. 2024 AsiaPacific Societies for ExtracellularVesicles and Chinese Society forExtracellular Vesicles, Guangzhou, China. (特邀报告,并担任分会主席和主持人)
4) 2024,10/8-12,报告题目《Schistosomiasis: From basics to DiagnosisandTherapy》. 3rd internationalparasitology conference ofPARACON2024, University of Veterinary and Animal Sciences(UVAS),Lahore, Pakistan. (特邀大会主旨报告,并担任会议主席)
5) 2024, 7/1-5,报告题目《Schistosomiasis: understanding basics toaccelerate diseaseelimination》. 2024 Sino-GermanParasitology Symposium, Wuhan, China. (特邀报告)
6) 2023, 8/14, 报告题目《Schistosomiasis: Understanding Basics toAccelerated DiseaseElimination》. University of thePhilippines, Diliman,Quezon City, Philippines. (特邀报告)
7) 2023,7/7-9, 报告题目《Schistosomiasis: understanding basicstoaccelerate disease elimination》. Sino-Micro23, Changchun,China. (特邀报告)
8) 2018,8/19-24, 报告题目《Schistosomajaponicum IAP and Teg20safeguardtegumental integrity by inhibiting cellular apoptosis》. 14thInternational Congress of Parasitology-NTD Asia 2018,Daegu, Korea (特邀报告)

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