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同济大学医学院副教授，博士生导师，上海市催化医学前沿科学研究基地骨干。近年来围绕分子影像探针在恶性肿瘤早期诊断中的重大需求，聚焦分子影像探针灵敏度和特异性不足等关键科学问题，开展了一系列研究。获得国自然面上项目、青年项目、上海市面上项目、上海市卫健委临床研究专项等项目资助。近年来，以第一/共一作者在ACS Nano（4篇），Biomaterials（2篇），Small，Chemical Science，Theranostics等国际期刊上共发表SCI论文16篇（其中IF＞10的10篇，部分入选封面、封底和ESI前1%高被引），并获授权3项国家发明专利。
1. 国家自然科学基金面上项目，2023.01-2026.12，在研，主持；
2. 同济大学自主原创基础研究项目，2022.11-2024.10，主持；
3. 国家自然科学基金青年项目，2019.01-2021.12，已结题，主持；
4. 上海市自然科学基金面上项目，2020.07-2023.06，在研，主持；
5. 上海市卫健委临床研究专项，2021.01-2023.12，在研，主持；
6. 中国博士后科学基金面上项目，2017.11-2019.05，已结题，主持。
1. 国家自然科学基金面上项目，2023.01-2026.12，在研，主持；
2. 同济大学自主原创基础研究项目，2022.11-2024.10，已结题，主持；
3. 国家自然科学基金青年项目，2019.01-2021.12，已结题，主持；
4. 上海市自然科学基金面上项目，2020.07-2023.06，已结题，主持；
5. 上海市卫健委临床研究专项，2021.01-2023.12，已结题，主持；
6. 中国博士后科学基金面上项目，2017.11-2019.05，已结题，主持。
发表论文
23. Zhuoyao Wu#, Weiwei Zeng#, Weitao Yang#, Jinyan Yi, Dinghua Liu, Yan Xu, Chang Liu, Kexin Bian, Hui Wang, Bingbo Zhang*, FAP-catalyzed in Situ Self-assembly of Magnetic Resonance Imaging Probe for Early and Precise Staging of Liver Fibrosis, Science Advances, 2025, 11, eadt6082.
22. Dinghua Liu, Hui Wang, Weitao Yang*, Yang Bai, Zhuoyao Wu, Tianming Cui, Kexin Bian, Jinyan Yi, Chunlin Shao,* and Bingbo Zhang*, One-Dose Bioorthogonal Gadolinium Nanoprobes for Prolonged Radiosensitization of Tumor. Small, 2025, 2500504.
21. Zhuoyao Wu, Weitao Yang*, and Bingbo Zhang*. Enzyme-Catalyzed Molecular MR Imaging of Tumor, Trends in Analytical Chemistry, 2024, 178, 117848.
20. Weitao Yang#, Cuijun Deng#, Xiudong Shi#, Yan Xu, Chenyu Dai, Hui Wang, Kexin Bian, Tianming Cui, and Bingbo Zhang*. Structural and Molecular Fusion MRI Nanoprobe for Differential Diagnosis of Malignant Tumors and Follow-Up Chemodynamic Therapy. ACS Nano, 2023, 17(4), 4009–4022.
19. Xiaoxv Geng, Kaixin Liu, Pengyuan Li, Huizhen Xing, Xiaoying Pei, Jin Chang*, Weitao Yang*, Xiaoli Wu*. A Multipronged Strategy for Encephalitis: Oxidative Stress Reduction and Inflammatory Microenvironment Modulation by a Neuroprotective Selenium-based Nanomedicine. Chemical Engineering Journal, 2024, 492, 152176.
18. Kaixin Liu, Shujun Chen, Xiaoxv Geng, Xiaoying Pei, Huizhen Xing, Xueying Zhang, Jin Chang, Weitao Yang*, and Xiaoli Wu*. Multifunctional Selenium-Based Metal Polyphenol Nanoparticles Impede the Pathological Cross-talk Between Reactive Oxygen Species and Inflammation in Sepsis. ACS Materials Letters, 2024, 6, 2434–2445.
17. Weitao Yang, Xiudong Shi, Yuxin Shi, Defan Yao, Shizhen Chen, Xin Zhou, and Bingbo Zhang*, Beyond the Roles in Biomimetic Chemistry: An Insight into the Intrinsic Catalytic Activity of an Enzyme for Tumor-Selective Phototheranostics, ACS Nano, 2018, 12 (12): 12169-12180.
16. Weitao Yang#, Weisheng Guo#, Wenjun Le, Guoxian Lv, Fuhe Zhang, Lei Shi, Xiuli Wang, Jun Wang, Sheng Wang, Jin Chang*, and Bingbo Zhang*. Albumin-Bioinspired Gd:CuS Nanotheranostic Agent for In Vivo Photoacoustic/Magnetic Resonance Imaging-Guided Tumor-Targeted Photothermal Therapy, ACS Nano, 2016, 10(11): 10245-10257.
15. Weitao Yang#, Chenyang Xiang#, Yan Xu, Shizhen Chen, Weiwei Zeng, Kai Liu, Xiao Jin, Xin Zhou*, and Bingbo Zhang*, Albumin-constrained large-scale synthesis of renal clearable ferrous sulfide quantum dots for T1-Weighted MR imaging and phototheranostics of tumors. Biomaterials, 2020, 255, 120186.
14. Weitao Yang, Xiaoli Wu, Yan Dou, Jin Chang*, Chenyang Xiang, Jiani Yu, JunWang, Xiuli Wang, Bingbo Zhang*, A human endogenous protein exerts multi-role biomimetic chemistry in synthesis of paramagnetic gold nanostructures for tumor bimodal imaging, Biomaterials, 2018, 161: 256-269.
13. Weitao Yang, Weisheng Guo, Xiaoqun Gong, Bingbo Zhang*, Sheng Wang, Na Chen, Wentao Yang, Yu Tu, Xiangming Fang, and Jin Chang*, Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR in Vivo Imaging. ACS Applied Materials & Interfaces, 2015, 7(33): 18759-18768.
12. Weitao Yang, Bingbo Zhang*, Porphyrin-based nanocomposites for tumor photodynamic therapy. MRS Bulletin, 2019, 44(3), 189-194.
11. Weitao Yang#, Weisheng Guo#, Jin Chang*, Bingbo Zhang*. Protein/peptide-templated biomimetic synthesis of inorganic nanoparticles for biomedical applications. Journal of Materials Chemistry B, 2017, 5, 401-417
10. Weitao Yang, Weisheng Guo, Jin Chang*, Bingbo Zhang*, Synthesis of Noble Metal Nanoclusters Based on Protein and Peptide as a Template. Acta Chim. Sinica, 2014, 72(12): 1209-1217.
9. Peiru Wang#, Weitao Yang#, Shuzhan Shen#, Chao Wu, Long Wen, Qian Cheng, Bingbo Zhang* and Xiuli Wang*，Differential Diagnosis and Precision Therapy of Two Typical Malignant Cutaneous Tumors Leveraging Their Tumor Microenvironment: A Photomedicine Strategy. ACS Nano, 2019, 13, 11168-11180. (并列第一)
8. Yan Xu#, Weitao Yang#, Yi Han#, Kexin Bian, Weiwei Zeng, Liangwen Hao, Hui Wang, Yingsheng Cheng, Peijun Wang, and Bingbo Zhang*. Biomimetic Molybdenum Sulfide-Catalyzed Tumor Ferroptosis and Bioimaging. Small, 2023, 2207544. (并列第一)
7. Liangwen Hao#, Weitao Yang#, Yan Xu#, Tianming Cui, Guoqi Zhu, Weiwei Zeng, KexinBian, Hongying Liang, Pengfei Zhang and Bingbo Zhang*. Engineering Light-Initiated Afterglow Lateral Flow Immunoassay for Infectious Disease Diagnostics. Biosensors and Bioelectronics, 2022, 212, 114411. (并列第一)
6. Yan Xu#, Weitao Yang#, Defan Yao, Kexin Bian, Weiwei Zeng, Kai Liu, Dengbin Wang and Bingbo Zhang*, An aggregation-induced emission dye-powered afterglow luminogen for tumor imaging. Chemical Science, 2020, 11, 419-428. (并列第一)
5. Xiudong Shi#, Weitao Yang#, Qiong Ma, Yang Lu, Yan Xu, Kexin Bian, Fengjun Liu, Chunzi Shi, Han Wang*, Yuxin Shi*, and Bingbo Zhang*，Hemoglobin-mediated biomimetic synthesis of paramagnetic O2-evolving theranostic nanoprobes for MR imaging-guided enhanced photodynamic therapy of tumor.Theranostics 2020, 10(25):11607-11621(并列第一).
4. Xiao Jin#, Weitao Yang#, Yan Xu, Kexin Bian, Bingbo Zhang*, Emerging strategies of activatable MR imaging probes and their advantages for biomedical applications，View, 2021, 2(5): 20200141. (Front Cover, Invited，并列第一)
3. Weisheng Guo#, Weitao Yang#, Bingbo Zhang*, Jin Chang*, and Xiaoyuan Chen*, Color-tunable Gd-Zn-Cu-In-S/ZnS quantum dots for dual modality magnetic resonance and fluorescence imaging, Nano Research, 2014, 7(11): 1581-1591. (并列第一)
2. Jiani Yu#, Weitao Yang#, Shige Xing, Jun Wang, Huanxing Han, Pengfei Zhang, Chenyang Xiang, and Bingbo Zhang*, Blended gold/MnO2@BSA nanoparticles for fluorometric and magnetic resonance determination of ascorbic acid, Microchimica Acta, 2019, 186 (2), 89. (并列第一)
1. Sheng Wang#, Weitao Yang#, Jin Chang*, Xiaoqun Gong* and Bingbo Zhang*, Multifunctional reduction-responsive SPIO&DOX-loaded PEGylated polymeric lipid vesicles for magnetic resonance imaging-guided drug delivery, Nanotechnology, 2016, 27(16): 165101. (并列第一).
授权发明专利：
1. 一种钼硫化合物-蛋白质纳米复合物及其制备方法和用途; 张兵波，徐琰，杨维涛，边可新，曾维薇，金骁，授权日期：2022.10.18；专利号：
ZL202110609745.8，授权公告号： CN 113332429 B
2. 一种具有聚集诱导发光特性的声敏剂及其制备方法; 张兵波，曾维薇，杨维涛，徐琰，授权日期：2021.10.08；专利号：ZL201911311985.9；
授权公告号： CN 111053901 B
3. 一种阳性造影剂及其制备和应用; 张兵波，杨维涛，徐琰，曾维薇，刘凯，授权日期：2021.04.02，专利号：ZL201911187524.5；授权公告号： CN 110755643 B
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