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同济大学医学院病理学与病理生理学系副教授,博士生导师。主要从事人神经发育机制及神经疾病发病机制的研究。以第一作者或通讯作者(含共同)发表SCI论文十余篇,主持或参与多项国家及省市级科研项目。
主持国家自然科学基金青年科学基金项目和上海市科委“科技创新行动计划”项目各一项,作为项目骨干参与两项国家重点研发计划。近5年以第一作者(含共同)或共同通讯作者发表SCI论文6篇,影响因子总计超过40分。申请国家发明专利一项。获得2021 STEM CELLS Young Investigator Award。
代表性文章:
1. Ma, L., Du, Y., Hui, Y., Li, N., Fan, B., Zhang,XJ., Li, X., Hong, W., Wu, Z., Zhang, S., Zhou, S., Xu, X., Zhou, Z., Jiang, C., Liu, L., Zhang, X. Developmental programming and lineage branching of early humantelencephalon. The EMBO Journal, 2021 Sep 24; e107277. doi: 10.15252/embj.2020107277.
2. Ma, L., Du, Y., Xu, X., Feng, H., Hui, Y.,Li, N., Jiang, G., Zhang, X., Li, X., Liu, L. β-catenin deletion inregional neural progenitors leads to congenitalhydrocephalus in mice. Neuroscience Bulletin, 2021 Aug30. doi: 10.1007/s12264-021-00763-z.
3. Xu, X.*, Du, Y.*,Ma,L.*,Zhang, S., Shi, L., Chen, Z., Zhou, Z., Hui, Y., Liu, Y., Fang, Y., Fan, B.,Liu, Z., Li, N., Zhou, S., Jianf, C., Liu, L., Zhang, X. Mapping germ-layerspecification preventing genes in hPSCs via genome-scale CRISPR screening. iScience, 2021, 24, 101926.
4. Shi, L., Li, W.,Liu, Y., Chen, Z., Hui, Y., Hao, P., Xu, X., Zhang, S., Feng, H., Zhang, B.,Zhou, S., Li, N., Xiao, L., Liu, L., Ma, L.#, Zhang, X.# Generation ofhypoimmunogenic human pluripotent stem cells via expression of membrane-boundand secreted β2m-HLA-G fusion proteins. StemCells, 2020, 38, 1423-1437.
5. Ma, L., Wang, Y., Hui, Y., Du, Y., Chen, Z., Feng,H., Zhang, S., Li, N., Song, J., Fang, Y., Xu, X., Shi, L., Zhang, B., Cheng,J., Zhou, S., Liu, L., Zhang, X. WNT/NOTCH Pathway Is Essential for theMaintenance and Expansion of Human MGE Progenitors. Stem Cell Reports, 2019, 12, 934-949. IF:7.765
6. Wang, Y.*, Xu, C.*,Ma, L.*, Mou, Y., Zhang, B., Zhou,S., Tian, Y., Trinh, J., Zhang, X., and Li, X.J. Drug screening with human SMN2reporter identifies SMN protein stabilizers to correct SMA pathology. Life Science Alliance, 2019, 2.

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