主持国家自然科学基金面上项目、国家自然科学基金青年基金、国家教育部博士点新教师基金、上海市自然科学基金、中央高校基本科研业务费专项基金等项目。为国家重点研发计划“主动健康和老龄化科技应对”专项“老年衰弱快速筛查评估量表的研发与建立”任务责任人。

为如皋衰老纵向队列Co-PI（Rugao Longevity and Ageing Study, RuLAS）。

近5年发表文章(Publication)：*通讯作者(corresponding author)，#并列第一(co-first author)

1.    HuangY#, Sun X#, Huang Q, Huang Q, Chen X, Zhou X, Chen H, Shen J, Gao M, Gong Y,Zhang H, Tang H, Wang X, Jiang X*, Zheng Y*, Yuan C*.Circulating metabolome in relation to cognitive impairment: a community-basedcohort of older adults. Transl Psychiatry. 2024 Nov 11;14(1):469. doi:10.1038/s41398-024-03147-9. （co-correspondingauthor)

2.    ZhangN#, Guo J#, Zhang M, Yu Y, Guo M, Xu H, Wang Z, Wu L, Wang X, Jiang X*.Sleep disturbances and intrinsic capacity trajectories among Chinese olderadults: The Rugao Longevity and Ageing Study. Geriatr Nurs. 2024 Sep 7;60:150-155.doi: 10.1016/j.gerinurse.2024.08.043. (corresponding author)

3.    DaiQ#, Ma Y#, Liu C, Zhao R, Chen Q, Chen W, Wang X, Jiang X*, Li S*.Association of 8-hydroxy-2’-deoxyguanosine with motoric cognitive risk inelderly Chinese people: RUGAO longevity and aging cross-sectional study. BMCGeriatr. 2024 Apr 11;24(1):331. doi: 10.1186/s12877-024-04943-0. （co-correspondingauthor)

4.    LiuHe#, Zhoutao Zheng#, Xueqin Li, Xingqi Cao, Jingyun Zhang, Chen Chen, YuebinLv, Chenkai Wu, Lisa C. Barry, Zhimin Ying*, Xiaoyan Jiang*, Xiaoming Shi, Zuyun Liu*. Association ofspouse’s health status with the onset of depressive symptoms in partnerevidence from the China Health and Retirement Longitudinal Study. J AffectDisord. 2023 Mar 15;325:177-184.  doi:10.1016/j.jad.2022.12.118.（co-correspondingauthor)

5.    HZhang#, M Sun#, Z Hu, Y Cao, M Hao, Y Li, L Jin, X Sun, X Wang, X Jiang*. Association ofArterial Stiffness with Functional Disability and Mobility Limitation: TheRugao Longitudinal Ageing Study. J Nutr Health Aging. 2022; 26(6):598-605.  doi: 10.1007/s12603-022-1802-z. (correspondingauthor)

6.    JYZhang#, SH Yu#, G Zhao, X Jiang*,YZhu*，Z Liu*. Associations of chronicdiarrheal symptoms and inflammatory bowel disease with sleep quality. FrontNeurol. 2022 Aug 24;13:858439. （co-correspondingauthor)

7.    YuanJL#, Zhao RX#, Ma YJ, Li XD, Zhou XM, Wang XF, Jiang XY*, Li SJ*. Prevalence/potential risk factors formotoric cognitive risk and its relationship to falls in Chinese elderly people:A cross-sectional study. Eur J Neurol. 2021; 28(8):2680-2687.  doi: 10.1111/ene.14884. （co-corresponding author)

8.    MaY#, Li X#, Pan Y, Zhao R, Wang X, JiangX*, Li S*.Cognitive frailty and falls in Chinese older people：a population-based longitudinal study. Eur JNeurol. 2021; 28(2):381-388.  doi:10.1111/ene.14572.（co-corresponding author)

9.    MaY#, Li X#, Pan Y, Zhao R, Wang X, JiangX*, Li S*. Cognitive frailty predicting death and disability in Chineseelderly. Neurol Res. 2021; 43(10):815-822. doi: 10.1080/01616412.2021.1939235. （co-corresponding author)

10.  GuoJH#, Shi JM#, Shi GP, Wang Y, Chu XF, Wang ZD, Yao S, Sun XH, Wang XF, Zhu YS*,Jiang XY*. Association Studyof Mitochondrial DNA Haplogroup D and C5178A Polymorphisms with Chronic KidneyDisease. Genet Test Mol Biomarkers. 2021; 25(8):546-550. doi:10.1089/gtmb.2020.0306. （co-correspondingauthor）

11.  ChenZ#, Jiang X#, Shi G, Wang Y,Chu X, Wang Z, Guo J, Zhu Y, Chen J, Wang X, Bao Z*. Social frailty andlongitudinal risk of depressive symptoms in a Chinese population: the RugaoLongevity and Aging Study. Psychogeriatrics. 2021; 21(4):483-490.  doi: 10.1111/psyg.12696.  （co-firstauthor）

12.  SunXH#, Ma T#, Yao S, Chen ZK, Xu WD, JiangXY*, Wang XF*. Associations of sleep quality and sleep duration withfrailty and pre-frailty in an elderly population Rugao longevity and ageingstudy. BMC Geriatr. 2020; 20(1):9. doi: 10.1186/s12877-019-1407-5. （co-corresponding author)

13.  MaT#, Sun XH#, Yao S, Chen ZK, Zhang JF, Xu WD, Jiang XY*, Wang XF*. Genetic Variants of HomocysteineMetabolism, Homocysteine, and Frailty - Rugao Longevity and Ageing Study.J NutrHealth Aging. 2020;24(2):198-204. doi: 10.1007/s12603-019-1304-9. （co-corresponding author)

14.  LiYX#, Jiang XY#, Stone C, MaYJ, Liu Q, Hu ZH, Li XD, Wang XF, Li SJ. A new physical-cognitive scale forassessment of frailty in Chinese Han elderly. Neurol Res. 2019; 41(8):728-733.doi: 10.1080/01616412.2019.1609164.（co-firstauthor）

15.  ShiGP#, Ma T#, Zhu YS, Wang ZD, Chu XF, Wang Y, Chen ZK, Xu WD, Wang XF, Guo JH, Jiang XY*. Frailty phenotype,frailty index and risk of mortality in Chinese elderly population- Rugaolongevity and ageing study. Arch Gerontol Geriatr. 2019; 80:115-119.（co-corresponding author）

16.  ZhangH, Hu Z, Jiang S, Hao M, Li Y, Liu Y, Jiang XY, Jin L, Wang X.Social frailty and the incidence of motoric cognitive risk syndrome in olderadults. Alzheimers Dement. 2024 Apr;20(4):2329-2339.

17.  Hao M#, Zhang H# Li Y#, Hu X,Hu Z, Jiang X, Wang J, Sun X, Liu Z, Davis D, Jin L*, Wang X*.Using physiological system networks to elaborate resilience across frailtystates. J Gerontol A Biol Sci Med Sci. 2024 Oct 1;79(10):glad243.  doi: 10.1093/gerona/glad243.

18.  Hao#M, Zhang H#, Jiang S, Hu Z, Jiang X, Wu J, Li Y, Jin L, Wang X.Metrics of Physiological Network Topology Are Novel Biomarkers to CaptureFunctional Disability and Health. J Gerontol A Biol Sci Med Sci. 2024 Dec11;80(1):glae268. doi: 10.1093/gerona/glae268.

19.  HaoM#, Zhang H#, Hu Z, Jiang X,Song Q, Wang X, Wang J, Liu Z*, Wang X*, Li Y*, Jin L*. Phenotype correlationsreveal the relationships of physiological systems underlying human ageing.Aging Cell. 2021; 20(12):e13519.

20.  ZhangH#, Hao M#, Hu Z#, Li Y, Jiang X,Wang J, Jin L, Liu Z, Wang X*, Sun X*. Association of immunity markers with therisk of incident frailty: the Rugao longitudinal aging study. Immun Ageing.2022 Jan 3;19(1):1

21.  ZhangH, Hao M, Li Y, Jiang X, WangM, Chen J, Wang X*, Sun X*.Glomerular filtration rate by different measures andalbuminuria are associated with risk of frailty: the Rugao Longitudinal AgeingStudy. Aging Clin Exp Res. 2022 Nov;34(11):2703-2711.

22.  ZhangH#, Shen H#, Gong W, Sun X, Jiang X,Wang J, Jin L, Xu X, Luo D*, Wang X*. Plasma Homocysteine and Macular Thicknessin Older Adults-the Rugao Longevity and Aging Study. Eye (Lond).2022;36(5):1050-1060.

23.  ZhangH#, Li Y#, Hao M, Jiang X,Wang J, Jin L, Bao Z*, Wang X*. Kidney function decline is associated with anaccelerated increase in plasma homocysteine in older adults: a longitudinalstudy. Br J Nutr. 2022;127(7):993-999.

24.  HZhang#, M Hao#, Z Hu, Y Li, X Hu, XJiang, Z Liu, X Sun*, X Wang*. Causal Association of Cardiac Functionby Magnetic Resonance Imaging with Frailty Index: A Mendelian RandomizationStudy. Phenomics, 2022, https://doi.org/10.1007/s43657-022-00072-z

25.  ZhangH#, Zhu Y#, Hao M, Wang J, Wang Z, Chu X, Bao Z, Jiang X, Shi G*, Wang X*. The modified Healthy Aging Indexis Associated with Mortality and Disability: The Rugao Longevity and AgeingStudy. Gerontology. 2021;67(5):572-580.

26.  ZhangH#, Zhu Y#, Gong W, Sun X, Jiang X,Wang J, Jin L, Xu X, Luo D*, Wang X*. Plasma Homocysteine and Macular Thicknessin Older Adults-the Rugao Longevity and Aging Study. Eye (Lond). 2022; 36(5):1050-1060.  doi: 10.1038/s41433-021-01549-3.

27.  ZhangH#, Li Y#, Hao M, Jiang X,Wang J, Jin L, Bao Z*, Wang X*. Kidney function decline is associated with anaccelerated increase in plasma homocysteine in older adults: a longitudinalstudy. BrJ Nutr. 2022;127(7):993-999.

28.  ChuX#, Zhang N#, Shi G, Wang Y, Wang Z, Guo J,Jiang X, Jin L, Wang X*, Zhu Y*. Frailty and Incident DepressiveSymptoms in a Chinese Sample: The Rugao Longevity and Ageing Study.Psychogeriatrics. 2020;20(5):691-698.

29.  WangZ#, Yao S#, Shi G, Wang Y, Shi J, Guo J, Zhu Y, Jiang X, Chu X*, Wang X*.Frailty index is associated withincreased risk of elevated BNP in an elderly population: the Rugao Longevityand Ageing Study. Aging Clin Exp Res. 2020;32(2):305-311.

30.  YaoS, Zhu Y , Shi G, Guo J, Wang Z, Chu X, JiangX, Jin L*, Wang X*. Associations of TNF-α -308 G>A and TNF-β 252A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. J NutrHealth Aging. 2020;24(3):358-363.

31.  ZhangN#, Shi GP#, Wang Y, Chu XF, Wang ZD, Shi JM, Guo JH, Wang YC, Yao S, Jiang XY, Zhu YS*, Wang XF*.Depressive symptoms are associated with incident frailty in a Chinesepopulation- the Rugao Longevity and Ageing Study. Aging Clin Exp Res.2020;32(11):2297-2302.

32.  YaoS#, Guo J#, Shi G, Zhu Y, Wang Y, Chu X, JiangX, Jin L, Wang Z*, Wang X*. Association Of BNP with frailty in elderlypopulation: Rugao Longevity and Ageing Study. J Nutr Health Aging.2019;23(1):73-78.