本团队的系统研究利用生物催化手段、构筑活性凝胶材料、解决生命健康问题，具体研究方向如下:

研究方向1:提出了酶促生理与界面聚合等温和成胶新方法

研究方向2:探索了创伤响应的酶催化体内成胶与再生修复

研究方向3:形成了肿瘤微环境响应的酶动力学诊疗新模式

研究方向4:拓展了载酶水合盐凝胶基于人机交互智能感知

课题组合影：

组内学生日常进行实验并处理数据：

国家自然科学基金杰出青年基金项目 2022-2026

国家自然科学基金面上项目 2018

海外青年高层次人才项目 2012-2016

国家重点研发计划 2016

国家自然科学基金面上项目 2015

国家自然科学基金面上项目 2013

以第一或通讯作者发表Nature, Nat. Commun., Adv. Mater., Angew. Chem. Int. Ed., J. Am. Chem. Soc., Acc. Chem. Res.等论文100余篇，其中影响因子大于10分论文50余篇。其中的代表性论文如下：

1. [1] Songyan Xi; Feng Tian; Gumi Wei; Xian He; Yinghui Shang; Ye Ju; Wenjun Li; Qinghua Lu*; Qigang Wang*; Reversible Dendritic-Crystal-Reinforced Polymer Gel for Bioinspired Adaptable Adhesive, Advanced Materials, 2021, 33: 2103174. (IF 30.897) 
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3. [2]Qi Zhang; Huaxing Xu; Chu Wu; Yinghui Shang; Qing Wu; Qingcong Wei; Qi Zhang; Yao Sun; Qigang Wang*; Tissue Fluid Triggered Enzyme Polymerization for Ultrafast Gelation and Cartilage Repair, Angewandte Chemie International Edition, 2021, 60: 19982-19987.  (IF 15.336)
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5. [3]Xing Qin#; Chu Wu#; Dechao Niu*; Limei Qin; Xia Wang*; Qigang Wang*; Yongsheng Li*; Peroxisome inspired hybrid enzyme nanogels for chemodynamic and photodynamic therapy, Nature Communications, 2021, 12: 5243.   (IF 14.919)
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7. [4]Xia Wang; Qigang Wang*; Enzyme-Laden Bioactive Hydrogel for Biocatalytic Monitoring and Regulation, Accounts of Chemical Research, 2021, 54: 1274-1287.  (IF 22.384)
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9. [5]Meiyuan Qi; Hui Pan; Hongdou Shen; Xianmeng Xia; Chu Wu; Xiaoke Han; Xingyue He; Wei Tong; Xia Wang*; Qigang Wang*; Nanogel Multienzyme Mimics Synthesized by Biocatalytic ATRP and Metal Coordination for Bioresponsive Fluorescence Imaging, Angewandte Chemie International Edition, 2020, 59: 11748-11753.    (IF 15.336)
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11. [6]Yinghui Shang; Chu Wu; Chengzhou Hang; Hongliang Lu; Qigang Wang*; Hofmeister‐Effect‐Guided Ionohydrogel Design as Printable Bioelectronic Devices, Advanced Materials, 2020, 32: 2000189.    (IF 30.897)
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13. [7]Qi Zhang#; Jiaojiao Wu#; Jingjing Wang#; Xia Wang; Chu Wu; Mengwei Chen; Qing Wu; Maciej S. Lesniak; Yongli Mi; Yu Cheng*; Qigang Wang*; A Neutrophil‐Inspired Supramolecular Nanogel for Magnetocaloric–Enzymatic Tandem Therapy, Angewandte Chemie International Edition, 2020, 59: 3732-3738.  (IF 15.336)
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15. [8]Ziyang Tai; Junjie Wei; Jie Zhou; Yue Liao; Chu Wu; Yinghui Shang; Baofeng Wang*; Qigang Wang*; Water-Mediated Crystallohydrate-Polymer Composite as a Phase-Change Electrolyte, Nature Communications, 2020, 11: 1843.    (IF 14.919)
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17. [9]Meihua Xie#; Wei Zhang#; Chengying Fan; Chu Wu; Qishuai Feng; Jiaojiao Wu; Yingze Li; Rui Gao; Zhenguang Li; Qigang Wang*; Yu Cheng*; Bin He*; Bioinspired Soft Microrobots with Precise Magneto‐Collective Control for Microvascular Thrombolysis, Advanced Materials, 2020, 32: 2000366.   (IF 30.897)
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19. [10]Junjie Wei; Gumi Wei; Yinghui Shang; Jie Zhou; Chu Wu; Qigang Wang*; Dissolution-Crystallization Transition within a Polymer Hydrogel for a Processable Ultratough Electrolyte, Advanced Materials, 2019, 31: 1900248.  (IF 30.897)