细菌耐药与致病的分子机制方向：

周迎：上海市扬帆专项2021；国自然青年 2023；Emerg Microbes Infect, 2020 (IF: 16.12)等7篇

郭银娟：国自然青年2020 Microbiol Spectr, 2022 (IF:9.03)等9篇

宛宝山：国自然青年2019 Front Cell Infect mi, 2019(IF:6.07)等4篇

余静怡：国自然青年 2023

尚永朋：国自然青年 2024

徐艳磊：国自然青年 2024

分枝杆菌诊断新技术的建立与应用方向：

乐军：十一五和十二五国家重大专项子课题

吴小翠：上海市公共卫生体系建设三年行动计划（2023—2025）学科人才项目；International Journal of Infectious Diseases, 2022(IF: 12.074)等8篇

基于生物信息学的肺部疾病发病机制的研究方向：

刘银：国自然青年2019；上海市“医苑新星”2022；浦江人才2022；Nat Cancer 2021, (IF: 23.013)等4篇

井博：国自然面上2024，国自然青年2018；Cancer Research, 2022(IF:13.81)

王洋：国自然青年2024；Hepatology, 2022 (IF: 17.29)

宋欢：国自然青年2024；上海市扬帆专项2022；Blood（IF:25.476）

主持课题18项，其中国家自然科学基金7项。

国家自然科学基金项目7项：

1.国家自然科学基金面上项目 亚抑菌浓度的夫西地酸通过SaeRS降低金黄色葡萄球菌毒力的机制研究 在研

2.国家自然科学基金面上项目  GtrA家族蛋白为增强金黄色葡萄球菌毒力的重要转录调节因子的研究 在研

3.国家自然科学基金面上项目  MraZ 通过影响毒力相关基因的表达增强金黄色葡萄球菌毒力的研究 结题

4.国家自然科学基金面上项目  金黄色葡萄球菌CapB2在致病中的作用及表达调控机制研究 结题

5.国家自然科学基金面上项目  表皮葡萄球菌表面锚定蛋白SesI在致病中的作用 结题

6.国家自然科学基金面上项目  SaeRS对耐甲氧西林金黄色葡萄球菌临床分离株杀白细胞素基因的表达调控机制研究 结题

7.国家自然科学基金面上项目  耐甲氧西金黄色葡萄球菌临床分离株Panton-Valentine杀白细胞素基因表达调控机制研究 结题

上海市科委项目1项：

1.基于靶向测序技术的分枝杆菌菌种鉴定方法学研究     在研

1. Characterization difference of typical KL1,KL2 and ST11-KL64 hypervirulent and carbapenem-resistant Klebsiella pneumoniae.  Drug Resistance Updates. 2023,67  IF:22.841

2. Phylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China. Emerging Microbes & Infections.2023,12  IF：19.568

3. Identification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence.Emerging Microbes & Infections.  2022,11  IF：19.568

4. Methicillin-resistant Staphylococcus aureus in China a multicenter longitudinal study and whole-genome sequencing.Emerging Microbes & Infections.2022,11  IF：19.568

5. Outbreak of IncX8 Plasmid–Mediated KPC-3–Producing Enterobacterales Infection, China. Emerging Infectious Diseases.2022,28:7  IF：16.126

6. Exploiting a conjugative endogenous CRISPR-Cas3 system to tackle multidrug-resistant Klebsiella pneumoniae.eBioMedicine.2023,88  IF：12.074

7. Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS. Intertional Journal of Infectious Disease.  2022，121  IF：12.074

8. Staphylococcus aureusPhenotypic and genomic analysis of the hypervirulent ST22 methicillin-resistant  in China. mSystems.  2023  IF：7.328

9. Phylogenetic Analysis and Virulence Characteristics of Methicillin-Resistant Staphylococcus aureus ST45 in China: a Hyper-Virulent Clone Associated with Bloodstream Infections. mSystems.  2023 27;8(2)  IF：7.328

10. Efficacy of the Xpert Mycobacterium tuberculosis/rifampicin assay for diagnosing sputum-smear negative or sputum-scarce pulmonary tuberculosis in bronchoalveolar lavage fluid. Intertional Journal of Infectious Disease. 2021,107   IF：12.074

11. Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9. mSystems.IF:6.4962021, 6:3,e00492-21

12. Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Shanghai, China. International Journal of Infectious Diseases.   2020,96  IF：12.074

13. Assessment of the Xpert MTB/RIF Ultra assay on rapid diagnosis of extrapulmonary tuberculosis. International Journal of Infectious Diseases.2019,81   IF：12.074

14. Subinhibitory Concentrations of Mupirocin Stimulate Staphylococcus aureus Biofilm Formation by Upregulating cidA. Antimicrobial Agents and Chemotherapy. 2019，64  IF：4.904  

15. Molecular Evolution and Adaptation of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) Sequence Type 9. mSystems. 2021, 6:3,e00492-21 IF：7.328

16. Subinhibitory Concentrations of Resveratrol Reduce Alpha-Hemolysin Production in Staphylococcus aureus Isolates by Downregulating saeRS. Emerging Microbes & Infections. 2018,7  IF：19.568

17. Multiplex PCRAnalysis for Rapid Detection of Klebsiella pneumoniae Carbapenem-Resistant(Sequence Type 258[ST258] and ST11) and Hypervirulent(ST23, ST65, ST86, and ST375)S trains. Journal of Clinical Microbiology. 2018,56  IF：4.054

18. In Vitro activity of ceftazidime-avibactam against carbapenem-resistant and hypervirulent Klebsiella pneumoniae isolates. Antimicrobial Agents and Chemotherapy.2018,62  IF：4.255  

19. Evaluation of the VITEK MS knowledge base version 3.0 for the identification of clinically relevant Mycobacterium species. Emerging Microbes & Infections.2018,7  IF：19.568

20. Coidentification of mcr-4.3 and blaNDM-1 in a Clinical Enterobacter cloacae Isolate from China. Antimicrobiol Agents and Chemotherapy. 2018,62 IF：4.256 

21. Determination of MIC Distribution and Mechanisms of Dreased Susceptibility to Bedaquiline among Clinical Isolates of Mycobacterium abscessus. Antimicrobiol Agents and Chemotherapy. 2018，62 IF： 4.256