主持多项国家“自然科学基金项目”、上海市“浦江人才项目”、上海市“教委重大创新项目”、同济大学创新项目等、以及与企业合作项目。

List of publications

代表性论文：

[55] "Enantioselective Synthesis of CF3S-containing Compounds via Ir-Catalyzed Allylic Alkylations of CF3S-substituted Functionalized Methylene Derivatives"

Tao Song, Xiaoming Zhao*, Xiaolin Wang

The Journal of Organic Chemistry,2019, 84, 15648-15654.

[54] "Chemoselective, Regioselective and Enantioselective Allylations of NH2OH under Ir Catalysis",

Jiteng Chen, Qingchun Liang,Xiaoming Zhao*

Organic Letters,2019, 21, 5383-5386 (Selected as supplementary cover and reproted by CBG资迅).

[53] "Selectfluor-promoted regioselective chlorination/bromination of 2-aminopyridines and 2-aminodiazines using LiCl/LiBr",

Jiao Hu, Gang Zhou, Yawei Tian,Xiaoming Zhao*,

Organic & Biomolecular Chemistry,2019, 17, 6342-6345.

[52] "Enantioselective copper-catalyzed desymmetrization of 1,3-diketones involving borylation of styrenes",

Purui Zheng, Xioyu Han, Jiao Hu,Xiaoming Zhao*, Tao XU*

Organic Letters,2019, 21, 6040-6044.

[51] "Ag-catalyzed selective fluorination of 6-substituted 2-aminopyrazines"

Yawei Tian, Mingzhu Zhao,Xiaoming Zhao*, Gang Zhou

Journal of Fluorine Chemistry,2019, 218, 111-115.

[50] "Silver-promoted selective fluorination of 2-aminopyrimidines: synthesis of 5-fluoro 2-aminopyrimidine derivatives",

Mingzhu Zhao, Juewang Cai,Xiaoming Zhao*

Organic Chemistry Frontiers,2019, 6, 426-431 (Selected as Front Cover).

[49] "Palladium-catalyzed cross-coupling of gem-bis(boronates) with aryl halides: an alternative to access quaternary a-aryl aldehydes",

Purui Zheng, Yujie Zhai,Xiaoming Zhao*, and Tao XU*

Organic Letters,2019, 21, 393-396.

[48] "Selective Fluorination of 4-Substituted 2-Aminopyridines and Pyridin-2(1H)-ones in Aqueous Solution",

Gang Zhou, Yawei Tian,Xiaoming Zhao*, Jiao Hu, Wenyan Dan,

Organic Letters,2018, 20, 4858-4861.

[47] "Difunctionalization of ketones via gem-bis(boronates) to synthesize quaternary carbon with high selectivity",

Purui Zheng, Yujie Zhai,Xiaoming Zhao*, Tao XU*

Chemical Communications,2018, 54, 13375-13378.

[46] "Selective fluorination of 2-aminopyrazine derivatives in aqueous phase",

Yawei Tian, Gang Zhhou,Xiaoming Zhao*, Wenyan Dan,

Acta Chim. Sinica,2018, 76, 962-966 (Invited paper).

[45] "Diastereoselective and Enantioselective Palladium-Catalyzed Allylic Substitution of Substituted Fluorinated Methylene Derivatives",

Tao Song,Xiaoming Zhao*, Jiao Hu, Wenyan Dan,

European Journal of Organic Chemistry,2018, 9, 1141-1144 (Highlighted as Outstanding Organics).

[44] "Diasteroselective and enantioselective Ir-catalyzed allylic substitutions of 1-substituted 1-fluoro-1-(arenesulfonyl)methylene derivatives",

Jiteng Chen,Xiaoming Zhao*, Wenyan Dan

The Journal of Organic Chemistry,2017, 82, 10693-10698.

[43] "Ag-assisted fluorination of unprotected 4,6-disubstituted 2-aminopyrimidines with Selectfluor" ,

Chenxi Wang, Juewang Cai, Min Zhang, andXiaoming Zhao*,

The Journal of Organic Chemistry,2017, 82, 1260-1265.

[42] "Cu-mediated oxidative trifluoromethylthiolation of arylboronic acids with (bpy)CuSCF3",

Mingzhu Zhao,Xiaoming Zhao*, Purui Zheng, Yawei Tian

Journal of Fluorine Chemistry,2017, 194, 73-79.

[41] "Chiral Sulfinamide Ligands, Pd-Catalyzed Asymmetric Allylic Alkylations Of Ethyl 2-Fluoroacetoacetate",

Mingzhu Zhao,Xiaoming Zhao*, Yawei Tian

Synlett,2017, 28, 1801-1806.

[40] "Chiral carbon–sulfur center formation via Pdcatalyzed asymmetric allylic thioetherification:

synthesis of allylic thioethers",

Junmei Cai, Juewang Cai, Purui Zheng, Xiaorong Wang* andXiaoming Zhao*

RSC Advances,2017, 7, 256-259.

[39] "Synthesis of 2,3,6-trisubstituted pyridines by transition-metal free cyclization of 1,3-diynes with amino acids",

Gang Zhou,Xiaoming Zhao*, Wenyan Dan

Tetrahedron Letters,2017, 58, 3085-3088.

[38] "Application of DMSO in the Synthesis of 1,4-Disubstituted (But-1-en-3-ynyl)methylthioethers",

Chuanchuan Cao, Liang Zhang, Gang Zhou, Wenyan Dan, Xiaorong Wang,* and

Xiaoming Zhao*

ChemistrySelect,2017, 2, 2985-2988.

[37] "Regioselective fluorination of 1-(2,2-dibromovinyl)benzene derivatives with wet tetran-bytylammonium fluoride: one-pot synthesis of (Z)-1-(2-bromo-1-fluorovinyl)benzenes",

Mingzhu Zhao, Ling Ming, Jialiang Tang andXiaoming Zhao*,

Organic Letters,2016, 18, 416-419 (This paper was highlighted byOrganic Chemistry Portal, 2017, Jan, see: www.organic-chemistry.org/abstracts/lit5/277.shtm).

[36] "Enantioselective synthesis of fluorinated branched allylic compounds via Ir-catalyzed allylations of functionalized fluorinated methylene derivatives",

Hongbo Zhang, Jiteng Chen,Xiaoming Zhao*

Organic & Biomolecular Chemistry,2016, 14, 7183-7186 (This paper was highlighted in Synfacts, 2016, 16, 947).

[35] "Synthesis of Chiral Fluorine-Containing Compounds via Pd-Catalyzed Asymmetrical Allylations of Dimethyl 2-fluoromalonate Using Sulfonamide-Pyridine Ligands",

Min Zhang, Zhao Mingzhu, Zheng Purui, Zhang Hongbo,Xiaoming Zhao*

Journal of Fluorine Chemistry,2016, 189, 13-21.

[34] "Highly efficient cycloaddition reaction of 1,3-diynes with sodium azide: a new way to 5-substituted-4-acetylene-1H-1,2,3-triazoles",

Jia-Liang Tang, Ling Ming, andXiao-Ming Zhao*

J. Heterocyclic Chem.,2016, 53, 1367-1370.

[33] "Synthesis of carbonyl 2-amino-pyrimidines via tandem regioselective heterocyclization of 1,3-diynes with guanidine and selective oxidation",

Liang Zhang, Mingzhu Zhang andXiaoming Zhao*,

Chemical Communications,2015, 51, 9370-9373.

[32] "Regioselective formation of 2,4,5-trisubstituted oxazoles through transition-Metal free heterocyclization of 1,3-diynes withN,O-bis(trimethylsiyl)acetamide",

Liang Zhang andXiaoming Zhao*,

Organic Letters,2015, 17, 184-186.

[31] "Enantioselective transformation of Na2SO3into allylic sulfonic acids under Pd catalysis",

Wei Liu,Xiaoming Zhao*, Hong-bo Zhang, Liang Zhang,

Chemical Communications,2015, 51, 655-657.

[30] "Synthesis of allylic sulfonic acids via regioselective Pd-catalyzed allylic substitutions of Na2SO3",

Wei Liu,Xiaoming Zhao*,

Tetrahedron Letters,2015, 56, 6800-6802.

[29] "Synthesis of Allyl Carbamates through the Regioselective Domino Reaction of

Amines, CO2, and Unsymmetrical Allyl Chlorides under Pd Catalysis",

Juewang Cai, Min Zhang, andXiaoming Zhao*,

Eur. J. Org. Chem.2015, 5925-5928.

[28] "Enantioselective synthesis of monofluorinated allylic compounds: Pd-catalyzed asymmetric allylations of dimethyl 2-fluoromalonate using newN-sulfinyl-based ligands,"

Ning Gao,Xiao-Ming Zhao,*Cheng-Si Cai and Jue-Wang Cai,

Org. Biomol. Chem.,2015, 13, 9551-9558.

[27] "Enantioselective transformation of allyl carbonates into branched allyl carbamates using amines and recycling CO2under iridium catalysis",

Shengcai Zheng, Min Zhang, andXiaoming Zhao*,

Chemistry a European Journal,2014, 20, 7216-7221 (highlighted by both a Frontispiece paper inChem.A -Eur. J. and by ChemViews).

[26] "Enantioselective domino reaction of CO2, amine and allyl chloride under iridium catalysis: formation of allyl carbamates",

Min Zhang,Xiaoming Zhao*, Shengcai Zheng,

Chemical Communications,2014, 50, 4455-4458.

[25] "Asymmetric Synthesis of Allylic Sulfonic Acids: Enantio- and Regioselective Iridium-Catalyzed Allylations of Na2SO3",

Wei Liu,Xiaoming Zhao*, Hongbo Zhang, Mingzhu Zhao,

Chemistry A European Journal,2014, 20, 16873-16876.

[24] "Transition-Metal-Free Heterocyclization of 1,3-Diynes with Nitriles in the Presence of Aqueous Potassium Hydroxide: Synthesis of 2,4-Disubstituted 5-[(E)-2-Phenylethenyl]-1,3-oxazoles"

Ming, Ling, Tang, Jialiang,Zhao, Xiaoming*,

Synthesis,2014, 46, 2499-25025.

[23] "Carbon–Phosphorus Bond Formation by Enantioselective Palladium-Catalyzed

Allylation of Diphenylphosphine Oxide",

Liang Zhang, Wei Liu, andXiaoming Zhao*

Eur. J. Org. Chem.,2014, 6846-6849.

[22] "Highly regioselective iridium-catalyzed and samarium-promoted coupling of allylic carbonates with ketones: New approach toward homoallylic alcohols",

Wei Liu, Liang Zhang, Weikang Yang, andXiaoming Zhao*

RSC Advances,2013, 3, 19917-19919.

[21] "Carbon-Sulfur Bond Formation via Metal-Catalyzed Allylations of Sulfur Nucleophiles",

Liu, Wei,Zhao, Xiaoming*,

Synthesis,2013, 45, 2051-2069 (Invited review).

[20] "Sulfur heterocyclization and 1,3-migration of silicon in reaction of 1,3-diynes with sodium triisopropylsilanethiolate: one-pot synthesis of 2,5-disubstituted 3-(triisopropylsilyl)thiophenes",

Tang, Jialiang, Ming, Ling,Zhao, Xiaoming*,

Synthesis,2013, 45, 1713-1718.

[19] "Synthesis of Chiral Allylic Thioesters: Enantio- and Regioselective Iridium-Catalyzed Allylations of KSAc"

Gao, Ning;Zhao, Xiaoming*,

European Journal of Organic Chemistry,2013, 13, 2708-2714.

[18] "Iridium-catalyzed allylic alkylationa of sodium phenyl selenide",

Ruiming Cui, Xinwen Guo, Shengcai Zheng,Xiaoming Zhao*

Chin. J. Chem.,2012, 30, 2647-2651.

[17] "Iridium-catalyzed enantioselective allylation of sodium 2-aminobenzenethiolate: an access to chiral benzo-fusedN, S-heterocycles",

Ning Gao, Xinwen Guo, Shengcai Zheng, Weikang Yang,Xiaoming Zhao*

Tetrahedron,2012, 68, 9413-9418 (This paper was highlighted inSynfacts,2013, 1, 71).

[16] "Enantioselective Iridium-catalyzed allylation of sodium benzotriazolide: an efficient way to chiral allylbenzotriazoles",

Min Zhang, Xinwen Guo, Shengcai Zheng,Xiaoming Zhao*

Tetrahedron Letters,2012, 53, 6995-6998.

[15] "Synthesis of 2,5-disubstituted thiophenes via metal-free sulfur heterocyclization of 1,3-diynes with sodium hydrosulfide",

Jialiang Tang, andXiaoming Zhao*

RSC Advances,2012, 2, 5488–5490.

[14] "One pot iridium-catalyzed asymmetrical double allylaitons of sodium Sulfide: a fast and economic way to construct chiral C2-symmetric bis(1-substituted-allyl)sulfane",

Shengcai Zheng, Weiqing Huang, Ning Gao, Ruimin Cui, Min Zhang, andXiaoming Zhao*

Chem. Commun.,2011, 45, 6969-6971.

[13] "Enantioselective Palladium-Catalyzed Allylic Substitution of Sodium Benzotriazoleide" ,

Wei Liu, Dazhi Zhang,Shengcai Zheng, Yinshuang Yue, Dongge Liu andXiaoming Zhao*

Eur. J. Org. Chem.,2011, 6288-6293 (This paper was highlighted inSynfacts, 2012,8, 188).

[12] "Carbon-sulfur bond formaton via Iridium-catalyzed asymmetrical allylation of aliphatic thiols"

Ning Gao, Shengcai Zheng, Weikang Yang, andXiaoming Zhao*

Organic Letters,2011,13, 1514-1516 (This paper was highlighted byOrganic Chemistry Portal,2011, Dec, see:www.organic-chemistry.org/abstracts/lit3/207.shtm).

[11] "Iridium-Catalyzed Asymmetric Allylation of Sodium Triisopropylsilanethiolate: a New Way to Form Chiral Thiols"

Weiqing Huang, Shengcai Zheng, Jialiang Tang, andXiaoming Zhao*

Org. Biomol. Chem.,2011, 9, 7897-7903.

[10] "Highly regioselective Pd-catalyzed allylic alkylation of fluorobis(phenylsulfonyl)methane",

Xiaoming Zhao*, Dengge Liu, Shengcai Zheng, Ning Gao

Tetrahedron Lett.,2011, 52, 665-667.

[9] "Regio- and Enantioselective Iridium-Catalyzed Allylation of Thiophenol: Synthesis of Enantiopure Allyl Phenyl Sulfides"

Shengcai Zheng, Ning Gao, Wei Liu, Dongge Liu,Xiaoming Zhao*,and Theodore Cohen

Organic Letters,2010, 12, 4454-4457 (This paper was highlighted inSynfacts, 2010,12, 1400).

[8] "Readily Prepared 3-Chloro-1-(phenylthio)propene, a Versatile Three-Carbon Annulating Agent"

Taoping Liu,Xiaoming Zhao*, Long Lu, and Theodore Cohen*

Organic Letters,2009, 11, 4576-4579.

[7] "Iridium-catalyzed Regio- and Enantioselective Allylic Alkylation of Fluorobis(phenylsulfonyl)methane"

Wenbo Liu, Shengcai Zheng, Hu He,Xiaoming Zhao*, Lixin Dai, and Shuli You *

Chem. Commun.,2009, 43, 6604-6606.

[6] "Iridium-Catalyzed Reactions of Trifluoromethylated Compounds with Alkenes: A Csp3-H Bond Activation a to the Trifluoromethyl Group"

Y. Guo;X. Zhao; D. Zhang; S-I. Murahashi

Angew. Chem. Int. Ed.,2009, 48, 2047-2049.

[5] "Efficient 1,4-addition of a-substituted fluoro(phenylsulfonyl)methane derivatives to a,b-unsaturated compounds"

G. K. Surya Prakash,*Xiaoming Zhao, Sujith Chacko, Fang Wang, Habiba, Vaghoo, and George A. Olah*

Beil. J. Org. Chem.,2008, 4, No. 17-20.

[4] "2-Phenylthio-3-bromopropene, a Valuable Synthons, Easily Prepared by a Simple Rearrangement"

Wenbo Chen,Xiaoming Zhao*, Long Lu and T. Cohen*

Organic Letters,2006, 8, 2807-2090.

[3] "A Platinum Acetylide Polymer with Sterically Demanding Substituents: Effect of Aggregation on the Triplet Excited State"

Xiaoming Zhao, Thomas Cardolaccia, Richard Farley, Khalil A. Abboud and Kirk S. Schanze.

Inorganic Chemistry,2005, 44, 2619-2627.

[2] "Bis-silyl substituted ferrocenylenes, including dicyanovinyl electron-withdrawing groups, as potential non-linear optical materials"

Xiaoming Zhao, Hemant Sharma, Francisco Cervantes-Lee and Keith H. Pannell, Gary J. Long, Ahmed M. Shahin

J. Organomet. Chem.2003, 686, 235-241.

[1] “Synthesis, and Crystal Growth and Structure ofN-(2-nitro-4-cyano-phenyl)-L-serine and Investigation of SHG activity”,

Xiaoming Zhao, Xing Chen, Lubai Cheng*

Mol. Cry. Liq. Cry., Sci. Technol., Sect. A,1998, 325, 7-11.

专利:

(1) 中国专利，赵晓明，王晨曦，一种银辅助的双取代的氨基嘧啶的对位单氟化反应方法及应用，申请，2016.11.29，201611070579.4

(2) 中国专利，赵晓明，赵明珠，一种银介导的4-取代-2-氨基-5-氟嘧啶类化合物的制备方法和应用，申请，2016.12.06，201611107951.4

(3) 中国专利，赵晓明，赵明珠，一种手性亚磺酰胺配体及其制备方法和应用，申请2016.12.08，201611121712.4

(4) 中国专利，赵晓明，张亮，一种2-胺基嘧啶类化合物及其制备方法，申请，2015.10.05，CN201510083798.5

(5) 中国专利，赵晓明，张敏，张红波，双手性亚砜-烯配体类化合物及其制备方法和应用，申请，2015.07.22，CN201510154854.X

(6) 中国专利，赵晓明，何天平，张敏，一种邻位取代烯丙基氨基甲酸酯类化合物及其制备方法，申请，2015.07.22,CN201410020287.4

(7) 中国专利，赵晓明，张敏，一种3-取代烯丙基氨基甲酸酯类化合物及其合成方法，申请，2015.06.24，CN201310712444.3

(8) 中国专利，赵晓明，张敏，双手性亚砜-烯配体类化合物及其制备方法和应用，申请，2015.04.02，201510154854.x

(9) 中国专利，赵晓明，杨为康，刘炜，一种烯丙基苯硫砜取代-1-丙烯类化合物与其合成方法，申请，2014.07.09，CN201310005864.8

(10) 中国专利，赵晓明，张亮，刘炜，张红波，一种烯丙基亚磷酸酯类化合物及其合成方法，申请，2014.10.05，CN201410301477.3

(11) 中国专利，赵晓明，张亮，刘炜，张红波，一种1,3-二取代烯丙基氧磷类化合物及其制备方法，申请，2014.10.29，CN201410336381.0

(12) 中国专利，赵晓明，蔡成思，高宁，蔡爵旺，3-三苯并三氮唑甲烷取代-1-(1,3-二烷基)丙烯类化合物及其合成方法，申请，2014.07.23，CN201410114645.8

(13) 中国专利，赵晓明，高宁，一种手性烯丙基硫醇羧酸酯及其合成方法，申请，2014.07.02，CN201210576163.5

(14) 中国专利，赵晓明，高宁，一种手性氮-硫双齿配体及其合成方法和应用，申请，2014.03.18，201410100202.3

(15) 中国专利，赵晓明，高宁，郑生财，杨为康，一种邻氨基苯基手性烯丙基硫醚化合物及其制备方法，申请，2013.05.15，CN201110351007.4

(16) 中国专利，赵晓明，张敏，郑生财，一种3-三氮唑基取代-1-丙烯类化合物及其合成方法，申请，2013.07.17，CN201210007640.6

(17) 中国专利，赵晓明，明玲，一种（Z）-2-溴-1-氟芳香族烯烃类化合物及其合成方法和用途，申请，2013.10.07，201310719547.2