中央高校青年教师科研创新能力支持项目

国家重点研发计划青年项目（结题1，在研1）

国自然优青（结题），面上（结题1，在研1），青年项目（结题）

上海市基础研究特区项目

1. Wei, Jiangbo*; Yu, Xianbin*;Yang, Lei*; Liu, Xuelian*; Gao, Boyang; Huang, Boxian; Dou, Xiaoyang; Liu, Jun;Zou, Zhongyu; Cui, Xiao-Long; Zhang, Li-Sheng; Zhao, Xingsen; Liu, Qinzhe; He,P Cody; Sepich-Poore, Caraline; Zhong, Nicole; Liu, Wenqiang; Li, Yanhe; Kou,Xiaochen; Zhao, Yanhong; Wu, You; Cheng, Xuejun; Chen, Chuan; An, Yiming; Dong,Xueyang; Wang, Huanyu; Shu, Qiang; Hao, Ziyang; Duan, Tao; He, Yu-Ying; Li,Xuekun; Gao, Shaorong#; Gao, Yawei#; He, Chuan#

FTO mediates LINE1 m6A demethylation and chromatinregulation in mESCs and mouse development

Science 2022 May27;376(6596):968-973

2.Jun Liu*, Xiaoyang Dou*, Chuanyuan Chen*, Chuan Chen,Chang Liu Meng Michelle Xu, Siqi Zhao, Bin Shen, Yawei Gao#, Dali Han#,Chuan He#

N6-methyladenosine of chromosome-associated regulatoryRNA regulates chromatin state and transcription

Science 2020 Jan31;367(6477):580-586.

3. XiaoyuLiu*, Chenfei Wang*, Wenqiang Liu*, Jingyi Li*, Chong Li, Xiaochen Kou, JiayuChen, Yanhong Zhao, Haibo Gao, Hong Wang, Yong Zhang#, Yawei Gao# & ShaorongGao#

Distinct features of H3K4me3 and H3K27me3 chromatindomains in pre-implantation embryos

Nature2016Sep 14;537(7621):558-562.

4. You Wu*, Xiaocui Xu*, Meijie Qi*,Chuan Chen, Mengying Li, Rushuang Yan, Xiaochen Kou, Yanhong Zhao, Wenqiang Li,Yanhe Li, Xuelian Liu, Meiling Zhang, Chengqi Yi, Hongbin Liu, Junhong Xiang,Hong Wang, Bin Shen#, Yawei Gao#, Shaorong Gao#

N 6-methyladenosineregulates maternal RNA maintenance in oocytes and timely RNA decay during mousematernal-to-zygotic transition

 Nat Cell Biol 2022Jun;24(6):917-927.

5.Wang Chenfei*,Chen Chuan*, Liu Xiaoyu*, Li Chong*, Wu Qiu, Chen Xiaolan, Yang Lingyue, KouXiaochen, Zhao Yanhong, Wang Hong, Gao Yawei#, Zhang Yong#,Gao Shaorong#

Dynamic nucleosome organization after fertilizationreveals regulatory factors for mouse zygotic genome activation. Cell Research (2022) 32, 801–813. 封面论文

6. Wen Wang; Rui Gao; Dongxu Yang; Mingli Ma; RugeZang; Xiangxiu Wang; Chuan Chen; Xiaochen Kou; Yanhong Zhao; Jiayu Chen;Xuelian Liu; Jiaxu Lu; Ben Xu; Juntao Liu; Yanxin Huang; Chaoqun Chen; HongWang; Shaorong Gao; Yong Zhang; Yawei Gao ; ADNP modulates SINE B2-derivedCTCFbinding sites during blastocyst formation in mice, GENES & DEVELOPMENT, 2024, DOI:10.1101/gad.351189.1

7. Wang C*,Liu X*, Gao Y*#, Yang L, Li C, LiuW, Chen C, Kou X, Zhao Y, Chen J, Wang Y, Le R, Wang H, Duan T, Zhang Y#, Gao S#.

Reprogramming of H3K9me3-dependent heterochromatin during mammalianembryo development.

NatCell Biol. 2018 May;20(5):620-631. doi: 10.1038/s41556-018-0093-4.

8. Gao Y*, Chen J*, Li K, Wu T,Huang B, Liu W, Kou X, Zhang Y, Huang H, Jiang Y, Yao C, Liu X, Lu Z, Xu Z,Kang L, Chen J, Wang H, Cai T, and Gao S

Replacement of Oct4 by Tet1 during iPSC InductionReveals an Important Role of DNA Methylation and Hydroxymethylation inReprogramming

CellStem Cell , 2013. 12(4): p. 453-69.封面论文

9. Gao, Rui*, Wang, Chenfei*, Gao, Yawei*, Xiu, Wenchao, Chen, Jiayu, Kou, Xiaochen; Zhao,Yanhong; Liao, Yuhan; Bai, Dandan; Qiao, Zhibin; Yang, Lei; Wang, Mingzhu;Zang, Ruge; Liu, Xiaoyu; Jia, Yanping; Li, Yanhe; Zhang, Yalin; Yin, Jiqing;Wang, Hong; Wan, Xiaoping; Liu, Wenqiang#; Zhang, Yong#; Gao, Shaorong#

Inhibition of Aberrant DNA Re-methylation ImprovesPost-implantation Development of Somatic Cell Nuclear Transfer Embryos

CellStem Cell, 2018.9.6, 23(3): 426~435.

10. Chuan Chen*,Wenqiang Liu*, Jiayin Guo, YuanyuanLiu, Xuelian Liu, Jun Liu, Xiaoyang Dou, Rongrong Le, Yixin Huang, Chong Li,Lingyue Yang, Xiaochen Kou, Yanhong Zhao, You Wu, Jiayu Chen, Hong Wang, BinShen#, Yawei Gao#& Shaorong Gao#

Nuclear m6A reader YTHDC1regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos. Protein Cell 12, 455–474 (2021). 封面论文

11. Yawei Gao*,Xiaoyu Liu*, Bin Tang*, Chong Li*, Zhaohui Kou, Lin Li, Wenqiang Liu, You Wu,Xiaochen Kou, Jingyi Li, Yanhong Zhao, Jiqing Yin, Hong Wang, She Chen, LujianLiao#, and Shaorong Gao#

Protein Expression Landscape of Mouse Embryos duringPre-implantation Development

CellReports 2017.12.26, 21(13): 3957~3969

12. You Wu,Wenqiang Liu, Jiayu Chen, Shuaitong Liu, Mingzhu Wang, Lei Yang, Chuan Chen,Meijie Qi, Yiwen Xu, Zhibin Qiao, Rushuang Yan, Xiaochen Kou, Yanhong Zhao, BinShen, Jiqing Yin, Hong Wang, Yawei Gao#and Shaorong Gao#

Nuclear Exosome Targeting Complex Core Factor Zcchc8Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic StemCells

CellReports. 2019 Nov 19;29(8):2461-2472