个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
1998年本科毕业于中国药科大学；2001年获得天津大学硕士学位；2004年获得中国科学院上海药物研究所博士学位。2005年赴香港大学医学院作访问学者。2004年7月至2009年8月就职于中国科学院上海药物研究所，历任助理研究员，副研究员。2009年进入同济大学工作，任副教授，教授。相关研究成果发表于国际顶级刊物Chemical Reviews(IF 45.6)、Circulation(IF 18.88)、Free Radical Biology and Medicine(IF 6.02)、Endocrinology以及Journal of Natural Products等本领域内重要期刊。迄今发表研究论文共50多篇，被SCI收录40多篇，申请国际专利1项(已授权)，中国专利5项（已授权3项）。主讲本科生《药学基础》课程，2011年获同济大学青年教师讲课竞赛团体二等奖、个人二等奖及最佳风范奖。现已主持或参与多项国家级以及省部级科研基金。入选2011年同济大学青年英才计划。担任上海市药学会天然药物化学专业委员会委员、国家科技奖励评审专家、教育部科技评价与评审系统专家、上海市科委项目评审专家、教育部学位论文评审专家、多家SCI论文的审稿人。
研究方向：
1、基于小分子探针的衰老分子生物学研究
2、神经退行性疾病的发病机制研究
3、延缓衰老及治疗衰老相关疾病天然活性药物的发现及作用机制研究
上传附件
支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg上传附件
支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg上传附件
支持扩展名：.rar .zip .doc .docx .pdf .jpg .png .jpeg1. Lin, H.; Gao, Y.; Zhang, C.; Ma, B.; Wu, M.; Cui, X.; Wang, H.,Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditiselegans. Front Aging Neurosci 2022, 14, 885145.
2. Cao, J.; Zhou, M. X.; Chen, X.; Sun, M.; Wei, C.; Peng, Q.;Cheng, Z.; Sun, W.; Wang, H., Sec-O-Glucosylhamaudol Inhibits RANKL-InducedOsteoclastogenesis by Repressing 5-LO and AKT/GSK3β Signaling. Frontiers in immunology 2022, 13, 880988.
3. Sun, M. L.; Chen, X. Y.; Cao, J.J.; Cui, X. H.; Wang, H. B., Polygonum multiflorum Thunb extract extended thelifespan and healthspan of Caenorhabditis elegans via DAF-16/SIR-2.1/SKN-1. Food Funct 2021, 12 (18), 8774-8786.
4. Cao, J.; Wang, S.; Wei, C.; Lin,H.; Zhang, C.; Gao, Y.; Xu, Z.; Cheng, Z.; Sun, W. C.; Wang, H. B., Agrimopholsuppresses RANKL-mediated osteoclastogenesis through Blimp1-Bcl6 axis andprevents inflammatory bone loss in mice. IntImmunopharmacol 2021, 90, 107137.
5. Chen, X. Y.; Liao, D. C.; Yu, Y.T.; Wei, C. M.; Xuan, L. Y.; Li, S.; Wang, H. B., Coix seed oil prolongslifespan and enhances stress resistance in Caenorhabditis elegans. Biogerontology 2020, 21 (2), 245-256.
6. Chen, X. Y.; Liao, D. C.; Sun, M. L.; Cui, X. H.; Wang, H. B.,Essential Oil of Acorus tatarinowii Schott Ameliorates Aβ-Induced Toxicity inCaenorhabditis elegans through an Autophagy Pathway. Oxid Med Cell Longev 2020,2020, 3515609.
7.Zhen-Zhou Yang, Ying-Ting Yu, Hong-Ru Lin, De-Chun Liao, Xiang-Huan Cui, Hong-Bing Wang*. Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans. Free Radical Biology and Medicine, 2018, 129:310-322.
8.Wei Chen#, Hong-Ru Lin#, Cong-Min Wei, Xiao-Hua Luo, Meng-Lu Sun, Zhen-Zhou Yang, Xin-Yan Chen, Hong-Bing Wang*, Echinacoside, a phenylethanoid glycoside from Cistanche deserticola, extends lifespan of Caenorhabditis elegans and protects from Aβ-induced toxicity, Biogerontology, 2018, 19:47–65.
9.Xiao-Hua Luo#, Ying-Ying Zhang#, Xin-Yan Chen, Meng-Lu Sun, Shan Li, Hong-Bing Wang*. Lignans from the roots of Acorus tatarinowii Schott ameliorate β amyloid-induced toxicity in transgenic Caenorhabditis elegans, Fitoterapia, 2016, 108, 5-8.
10.Hong-Bing Wang*, Xiao-Yang Wang, Li-Ping Liu, Guo-Wei Qin, Ting-Guo Kang. Tigliane Diterpenoids from the Euphorbiaceae and Thymelaeaceae, Chemial Reviews, 2015, 115: 2975-3011.
11.Li-ping Liu, Kun Han, Wei Chen, Ying-ying Zhang, Lin-jiang Tong, Ting Peng, Hua Xie, Jian Ding, Hong-Bing Wang*. Topoisomerase II inhibitors from the roots of Stellera chamaejasme L., Bioorganic & Medicinal Chemistry, 2014, 22, 4198-4203.
12.Hong-Bing Wang, Wei-Feng Gu, Wen-Jing Chu, Sheng Zhang, Xi-Can Tang, and Guo-Wei Qin.* Monoterpene Glucosides from Paeonia lactiflora. J. Nat. Prod. 2009, 72 (7), 1321-1324.
13.Ai-min Xu*, Hong-Bing Wang, Guo-wei Qin, et al. Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice, Endocrinology, 2009, 150, 625-633.
14.Gui-Rong Li*, Hong-Bing Wang, Guo-Wei Qin, et al. Acacetin, a Natural Flavone, Selectively Inhibits Human Atrial Repolarization Potassium Currents and Prevents Atrial Fibrillation in Dogs, Circulation, 2008, 117, 2449-2457.
文件上传中...
同济大学
